Direct p53 effectors Gene Set

Dataset PID Pathways
Category structural or functional annotations
Type pathway
External Link http://public.ndexbio.org/#/network/67c3b75d-6191-11e5-8ac5-06603eb7f303
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Genes

135 proteins participating in the Direct p53 effectors pathway from the PID Pathways dataset.

Symbol Name
AFP alpha-fetoprotein
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2
APAF1 apoptotic peptidase activating factor 1
APC adenomatous polyposis coli
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ATF3 activating transcription factor 3
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL2 B-cell CLL/lymphoma 2
BCL2A1 BCL2-related protein A1
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BCL2L2 BCL2-like 2
BCL6 B-cell CLL/lymphoma 6
BDKRB2 bradykinin receptor B2
BID BH3 interacting domain death agonist
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTG2 BTG family, member 2
CARM1 coactivator-associated arginine methyltransferase 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCNB1 cyclin B1
CCNG1 cyclin G1
CCNK cyclin K
CD82 CD82 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
COL18A1 collagen, type XVIII, alpha 1
CREBBP CREB binding protein
CSE1L CSE1 chromosome segregation 1-like (yeast)
CTSD cathepsin D
CX3CL1 chemokine (C-X3-C motif) ligand 1
DDB2 damage-specific DNA binding protein 2, 48kDa
DDIT4 DNA-damage-inducible transcript 4
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DGCR8 DGCR8 microprocessor complex subunit
DKK1 dickkopf WNT signaling pathway inhibitor 1
DROSHA drosha, ribonuclease type III
DUSP1 dual specificity phosphatase 1
DUSP5 dual specificity phosphatase 5
E2F1 E2F transcription factor 1
E2F2 E2F transcription factor 2
E2F3 E2F transcription factor 3
EDN2 endothelin 2
EGFR epidermal growth factor receptor
EP300 E1A binding protein p300
EPHA2 EPH receptor A2
FAS Fas cell surface death receptor
FDXR ferredoxin reductase
FOXA1 forkhead box A1
GADD45A growth arrest and DNA-damage-inducible, alpha
GDF15 growth differentiation factor 15
GPX1 glutathione peroxidase 1
HDAC2 histone deacetylase 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIC1 hypermethylated in cancer 1
HTT huntingtin
IGFBP3 insulin-like growth factor binding protein 3
IRF5 interferon regulatory factor 5
JMY junction mediating and regulatory protein, p53 cofactor
JUN jun proto-oncogene
LIF leukemia inhibitory factor
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MET MET proto-oncogene, receptor tyrosine kinase
MLH1 mutL homolog 1
MMP2 matrix metallopeptidase 2
MSH2 mutS homolog 2
NDRG1 N-myc downstream regulated 1
NFYA nuclear transcription factor Y, alpha
NFYB nuclear transcription factor Y, beta
NFYC nuclear transcription factor Y, gamma
NLRC4 NLR family, CARD domain containing 4
PCBP4 poly(rC) binding protein 4
PCNA proliferating cell nuclear antigen
PERP PERP, TP53 apoptosis effector
PIDD1 p53-induced death domain protein 1
PLK3 polo-like kinase 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POU4F1 POU class 4 homeobox 1
POU4F2 POU class 4 homeobox 2
PPM1J protein phosphatase, Mg2+/Mn2+ dependent, 1J
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PRDM1 PR domain containing 1, with ZNF domain
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRMT1 protein arginine methyltransferase 1
PTEN phosphatase and tensin homolog
PYCARD PYD and CARD domain containing
RB1 retinoblastoma 1
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RGCC regulator of cell cycle
RNF144B ring finger protein 144B
RPS27L ribosomal protein S27-like
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
S100A2 S100 calcium binding protein A2
SCN3B sodium channel, voltage gated, type III beta subunit
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SESN1 sestrin 1
SFN stratifin
SH2D1A SH2 domain containing 1A
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SNAI2 snail family zinc finger 2
SP1 Sp1 transcription factor
SPP1 secreted phosphoprotein 1
STEAP3 STEAP family member 3, metalloreductase
TADA2B transcriptional adaptor 2B
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TFDP1 transcription factor Dp-1
TGFA transforming growth factor, alpha
TIGAR TP53 induced glycolysis regulatory phosphatase
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TP53 tumor protein p53
TP53BP2 tumor protein p53 binding protein 2
TP53I3 tumor protein p53 inducible protein 3
TP53INP1 tumor protein p53 inducible nuclear protein 1
TP63 tumor protein p63
TP73 tumor protein p73
TRIAP1 TP53 regulated inhibitor of apoptosis 1
TRRAP transformation/transcription domain-associated protein
TSC2 tuberous sclerosis 2
TYRP1 tyrosinase-related protein 1
VCAN versican
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
ZNF385A zinc finger protein 385A