Digestive System Neoplasms Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

31 genes associated with the Digestive System Neoplasms phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
EGFR epidermal growth factor receptor
FEN1 flap structure-specific endonuclease 1
GCLC glutamate-cysteine ligase, catalytic subunit
KRAS Kirsten rat sarcoma viral oncogene homolog
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIR146A microRNA 146a
MIR196A2 microRNA 196a-2
MLH1 mutL homolog 1
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MSH2 mutS homolog 2
MSH6 mutS homolog 6
NQO1 NAD(P)H dehydrogenase, quinone 1
PLCE1 phospholipase C, epsilon 1
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
TGFB1 transforming growth factor, beta 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TP53 tumor protein p53
TP73 tumor protein p73
VEGFA vascular endothelial growth factor A