Diabetes Mellitus, Type 2 Gene Set

Dataset dbGAP Gene-Trait Associations
Category disease or phenotype associations
Type trait
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Genes

86 genes associated with the trait Diabetes Mellitus, Type 2 in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

Symbol Name Standardized Value
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 2.23422
MADD MAP-kinase activating death domain 2.16495
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 1.9255
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 1.83195
PCSK1 proprotein convertase subtilisin/kexin type 1 1.59958
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 1.47689
MAEA macrophage erythroblast attacher 1.41424
SLC30A8 solute carrier family 30 (zinc transporter), member 8 1.33123
FTO fat mass and obesity associated 1.30017
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 1.23542
GLIS3 GLIS family zinc finger 3 1.16559
JAZF1 JAZF zinc finger 1 1.14626
AP3S2 adaptor-related protein complex 3, sigma 2 subunit 0.995026
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 0.965948
HMG20A high mobility group 20A 0.955241
PRC1 protein regulator of cytokinesis 1 0.922056
ZFAND3 zinc finger, AN1-type domain 3 0.922056
HNF4A hepatocyte nuclear factor 4, alpha 0.907793
PTPRD protein tyrosine phosphatase, receptor type, D 0.866561
TP53INP1 tumor protein p53 inducible nuclear protein 1 0.862644
THADA thyroid adenoma associated 0.862644
SRR serine racemase 0.820059
SGSM2 small G protein signaling modulator 2 0.820059
RPSAP52 ribosomal protein SA pseudogene 52 0.807263
TYK2 tyrosine kinase 2 0.807263
ANK1 ankyrin 1, erythrocytic 0.763999
WFS1 Wolfram syndrome 1 (wolframin) 0.763999
PEPD peptidase D 0.763999
OASL 2'-5'-oligoadenylate synthetase-like 0.731179
KCNK16 potassium channel, two pore domain subfamily K, member 16 0.731179
KCNK17 potassium channel, two pore domain subfamily K, member 17 0.731179
SDHAF4 succinate dehydrogenase complex assembly factor 4 0.711358
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.711358
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 0.696869
NOTCH2 notch 2 0.696869
RBMS1 RNA binding motif, single stranded interacting protein 1 0.696869
SNX7 sorting nexin 7 0.609816
CMIP c-Maf inducing protein 0.585749
PCNXL2 pecanex-like 2 (Drosophila) 0.567219
PDZRN3 PDZ domain containing ring finger 3 0.539181
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.527821
CDKN2B-AS1 CDKN2B antisense RNA 1 0.50084
HNF1B HNF1 homeobox B 0.443956
GAS2 growth arrest-specific 2 0.443956
PPARG peroxisome proliferator-activated receptor gamma 0.443956
SORCS2 sortilin-related VPS10 domain containing receptor 2 0.428557
PALM2 paralemmin 2 0.406869
STEAP1B STEAP family member 1B 0.378873
PTPRM protein tyrosine phosphatase, receptor type, M 0.378873
ACHE acetylcholinesterase (Yt blood group) 0.356676
TCERG1L transcription elongation regulator 1-like 0.356676
PCSK2 proprotein convertase subtilisin/kexin type 2 0.356676
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 0.356676
SYK spleen tyrosine kinase 0.356676
HDAC9 histone deacetylase 9 0.340479
SVIP small VCP/p97-interacting protein 0.33862
PEX5L peroxisomal biogenesis factor 5-like 0.323533
FGGY FGGY carbohydrate kinase domain containing 0.323533
CR2 complement component (3d/Epstein Barr virus) receptor 2 0.323533
NRG1 neuregulin 1 0.323533
HIGD1C HIG1 hypoxia inducible domain family, member 1C 0.323533
PAPL iron/zinc purple acid phosphatase-like protein 0.29992
CRTAC1 cartilage acidic protein 1 0.29992
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 0.29992
LPIN2 lipin 2 0.29992
TPK1 thiamin pyrophosphokinase 1 0.29992
PLS1 plastin 1 0.29992
SH3BP4 SH3-domain binding protein 4 0.29992
ARHGAP26 Rho GTPase activating protein 26 0.207632
HIPK2 homeodomain interacting protein kinase 2 0.196934
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 0.192799
CORO1C coronin, actin binding protein, 1C 0.170455
RTL1 retrotransposon-like 1 0.166172
MAP3K13 mitogen-activated protein kinase kinase kinase 13 0.157924
VSIG10 V-set and immunoglobulin domain containing 10 0.154262
PLB1 phospholipase B1 0.101817
PTPRG protein tyrosine phosphatase, receptor type, G 0.088141
PRKCA protein kinase C, alpha 0.08405
CNBD1 cyclic nucleotide binding domain containing 1 0.082091
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 0.079128
SYNE1 spectrin repeat containing, nuclear envelope 1 0.076577
C1ORF204 chromosome 1 open reading frame 204 0.076093
TMEM108 transmembrane protein 108 0.068688
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1 0.066299
SETBP1 SET binding protein 1 0.066043
MAST4 microtubule associated serine/threonine kinase family member 4 0.063002