Diabetes Mellitus, Type 1 Gene Set

Dataset dbGAP Gene-Trait Associations
Category disease or phenotype associations
Type trait
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Genes

75 genes associated with the trait Diabetes Mellitus, Type 1 in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

Symbol Name Standardized Value
HLA-DRA major histocompatibility complex, class II, DR alpha 2.98871
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 2.75396
C6ORF10 chromosome 6 open reading frame 10 2.66684
INS insulin 2.64374
INS-IGF2 INS-IGF2 readthrough 2.64374
C6ORF47 chromosome 6 open reading frame 47 2.47777
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 2.46766
NOTCH4 notch 4 2.42194
PRRC2A proline-rich coiled-coil 2A 2.40984
BAG6 BCL2-associated athanogene 6 2.36988
PPT2 palmitoyl-protein thioesterase 2 2.34625
HSPA1L heat shock 70kDa protein 1-like 2.33369
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 2.31725
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 2.31003
VWA7 von Willebrand factor A domain containing 7 2.2975
TNXB tenascin XB 2.27686
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 2.27046
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 2.26105
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 2.26105
HLA-DOB major histocompatibility complex, class II, DO beta 2.23974
HSPA1B heat shock 70kDa protein 1B 2.22821
MICB MHC class I polypeptide-related sequence B 2.20992
STK19 serine/threonine kinase 19 2.15161
DXO decapping exoribonuclease 2.15161
ZBTB12 zinc finger and BTB domain containing 12 2.14335
C2 complement component 2 2.14335
CFB complement factor B 2.13552
MSH5 mutS homolog 5 2.13069
SLC44A4 solute carrier family 44, member 4 2.12619
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 2.04545
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.04545
BTNL2 butyrophilin-like 2 2.03986
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 2.03612
IL2RA interleukin 2 receptor, alpha 1.79399
SH2B3 SH2B adaptor protein 3 1.79079
ERBB3 erb-b2 receptor tyrosine kinase 3 1.61174
IGF2 insulin-like growth factor 2 1.50114
CLEC16A C-type lectin domain family 16, member A 1.33123
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 1.32039
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.30017
CUX2 cut-like homeobox 2 1.27677
CTSH cathepsin H 1.20587
PTPN2 protein tyrosine phosphatase, non-receptor type 2 1.19892
IFIH1 interferon induced with helicase C domain 1 1.16559
KIAA1109 KIAA1109 1.09046
GSDMB gasdermin B 1.08574
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 1.03374
GLIS3 GLIS family zinc finger 3 1.03374
FCRL3 Fc receptor-like 3 1.01477
SIRPG signal-regulatory protein gamma 1.01477
CD69 CD69 molecule 0.995026
PRKD2 protein kinase D2 0.982475
LMO7 LIM domain 7 0.960111
TYK2 tyrosine kinase 2 0.944178
MEG3 maternally expressed 3 (non-protein coding) 0.944178
CD226 CD226 molecule 0.862644
UBASH3A ubiquitin associated and SH3 domain containing A 0.836775
EFR3B EFR3 homolog B (S. cerevisiae) 0.807263
LOC399716 uncharacterized LOC399716 0.807263
SKAP2 src kinase associated phosphoprotein 2 0.796965
GAB3 GRB2-associated binding protein 3 0.774665
CLEC2D C-type lectin domain family 2, member D 0.685324
PRKCQ protein kinase C, theta 0.64828
PGM1 phosphoglucomutase 1 0.567219
IL2 interleukin 2 0.552134
DNAH2 dynein, axonemal, heavy chain 2 0.552134
HPSE2 heparanase 2 (inactive) 0.518003
LPAR3 lysophosphatidic acid receptor 3 0.443956
TNP2 transition protein 2 (during histone to protamine replacement) 0.406869
ADAD1 adenosine deaminase domain containing 1 (testis-specific) 0.406869
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.378873
FSTL4 follistatin-like 4 0.356676
IL25 interleukin 25 0.33862
CAPSL calcyphosine-like 0.310838
IL7R interleukin 7 receptor 0.310838