Diabetes Mellitus, Type 1 Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D003922
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Genes

185 genes/proteins associated with the disease Diabetes Mellitus, Type 1 from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
HP haptoglobin 2.88009
GLIS3 GLIS family zinc finger 3 2.88009
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 2.88009
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 2.88009
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 2.88009
CAT catalase 2.88009
NOS3 nitric oxide synthase 3 (endothelial cell) 2.88009
IL10 interleukin 10 2.88009
IL19 interleukin 19 2.88009
PAX4 paired box 4 2.88009
CD69 CD69 molecule 2.88009
CRP C-reactive protein, pentraxin-related 2.88009
IL2RA interleukin 2 receptor, alpha 2.88009
CHRM2 cholinergic receptor, muscarinic 2 2.88009
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 2.88009
NOS1 nitric oxide synthase 1 (neuronal) 2.88009
CCL20 chemokine (C-C motif) ligand 20 2.88009
FOXP3 forkhead box P3 2.88009
IFNG interferon, gamma 2.88009
CLEC16A C-type lectin domain family 16, member A 2.88009
TNF tumor necrosis factor 2.88009
CASP12 caspase 12 (gene/pseudogene) 2.88009
IGF1 insulin-like growth factor 1 (somatomedin C) 2.88009
INS insulin 2.88009
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 2.88009
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 2.88009
C1QTNF6 C1q and tumor necrosis factor related protein 6 2.88009
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 2.88009
SH2B3 SH2B adaptor protein 3 2.88009
CTSH cathepsin H 2.88009
IL27 interleukin 27 2.88009
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 2.88009
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.88009
IL20 interleukin 20 2.88009
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 2.88009
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 2.88009
DDIT3 DNA-damage-inducible transcript 3 2.88009
HNF1A HNF1 homeobox A 2.88009
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 2.88009
FGF21 fibroblast growth factor 21 2.88009
CP ceruloplasmin (ferroxidase) 2.88009
PRKCQ protein kinase C, theta 2.88009
CALR calreticulin 1.38752
PRKCA protein kinase C, alpha 1.38185
EPO erythropoietin 1.37532
NGF nerve growth factor (beta polypeptide) 1.37303
EDN1 endothelin 1 1.37246
NPPB natriuretic peptide B 1.36361
SOD2 superoxide dismutase 2, mitochondrial 1.36332
G6PD glucose-6-phosphate dehydrogenase 1.35906
XDH xanthine dehydrogenase 1.35069
TGFB1 transforming growth factor, beta 1 1.31446
CD14 CD14 molecule 1.31148
IL1B interleukin 1, beta 1.30727
BCL2L1 BCL2-like 1 1.2861
SOD1 superoxide dismutase 1, soluble 1.28395
FN1 fibronectin 1 1.28333
MAPK3 mitogen-activated protein kinase 3 1.28149
FAS Fas cell surface death receptor 1.28058
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 1.27751
IL2 interleukin 2 1.27347
MAPK1 mitogen-activated protein kinase 1 1.2707
GPX1 glutathione peroxidase 1 1.26267
BCL2 B-cell CLL/lymphoma 2 1.2456
CYBA cytochrome b-245, alpha polypeptide 1.24275
BAD BCL2-associated agonist of cell death 1.23962
SPP1 secreted phosphoprotein 1 1.23806
APOE apolipoprotein E 1.23712
HMOX1 heme oxygenase 1 1.22948
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.22916
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.22177
PPARG peroxisome proliferator-activated receptor gamma 1.22177
PINK1 PTEN induced putative kinase 1 1.21501
NOS2 nitric oxide synthase 2, inducible 1.2137
S100B S100 calcium binding protein B 1.20719
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 1.2046
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.19672
PRODH proline dehydrogenase (oxidase) 1 1.18948
GSTM1 glutathione S-transferase mu 1 1.18816
ACTB actin, beta 1.18816
CD44 CD44 molecule (Indian blood group) 1.18159
APP amyloid beta (A4) precursor protein 1.18159
VEGFA vascular endothelial growth factor A 1.18093
EGR1 early growth response 1 1.17168
NOX4 NADPH oxidase 4 1.16766
B2M beta-2-microglobulin 1.16766
IL12B interleukin 12B 1.166
PRKCD protein kinase C, delta 1.16567
GRB2 growth factor receptor-bound protein 2 1.16236
NOX1 NADPH oxidase 1 1.15526
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.15324
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.15189
MPO myeloperoxidase 1.15055
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.14575
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.14473
SFTPB surfactant protein B 1.14438
NOX3 NADPH oxidase 3 1.1437
ALAD aminolevulinate dehydratase 1.14302
SOD3 superoxide dismutase 3, extracellular 1.14302
BIRC3 baculoviral IAP repeat containing 3 1.14268
PPARA peroxisome proliferator-activated receptor alpha 1.13827
BMP6 bone morphogenetic protein 6 1.13415
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.13381
EDNRA endothelin receptor type A 1.13041
LEP leptin 1.1253
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.12014
BAX BCL2-associated X protein 1.11911
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.11843
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.11501
SP7 Sp7 transcription factor 1.11325
S100A8 S100 calcium binding protein A8 1.1122
GSR glutathione reductase 1.10907
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.10734
VIM vimentin 1.10493
CCL2 chemokine (C-C motif) ligand 2 1.10282
E2F8 E2F transcription factor 8 1.10282
FASLG Fas ligand (TNF superfamily, member 6) 1.10211
SKA1 spindle and kinetochore associated complex subunit 1 1.10211
JAK2 Janus kinase 2 1.10069
KLF2 Kruppel-like factor 2 1.09963
TFRC transferrin receptor 1.09927
RETN resistin 1.09681
BMP7 bone morphogenetic protein 7 1.09681
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.09011
IRS1 insulin receptor substrate 1 1.08975
RRM2 ribonucleotide reductase M2 1.08975
IL6 interleukin 6 1.0894
DSEL dermatan sulfate epimerase-like 1.08868
ODC1 ornithine decarboxylase 1 1.08762
PDIA4 protein disulfide isomerase family A, member 4 1.08549
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.07875
EDNRB endothelin receptor type B 1.07875
GPX3 glutathione peroxidase 3 1.07875
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.0784
SOX9 SRY (sex determining region Y)-box 9 1.07696
KLF5 Kruppel-like factor 5 (intestinal) 1.07696
TGFB2 transforming growth factor, beta 2 1.07696
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.07625
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.07376
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.07234
HLF hepatic leukemia factor 1.07163
ATF6 activating transcription factor 6 1.07163
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.06661
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.06515
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.05864
AGTR1 angiotensin II receptor, type 1 1.05864
CRELD2 cysteine-rich with EGF-like domains 2 1.05793
LCN2 lipocalin 2 1.05648
CSF1 colony stimulating factor 1 (macrophage) 1.05573
BTG2 BTG family, member 2 1.05498
LTF lactotransferrin 1.05349
ATF4 activating transcription factor 4 1.05312
CD38 CD38 molecule 1.05312
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.04868
PLD1 phospholipase D1, phosphatidylcholine-specific 1.04831
CAV1 caveolin 1, caveolae protein, 22kDa 1.04831
CXCL9 chemokine (C-X-C motif) ligand 9 1.04794
MRPS7 mitochondrial ribosomal protein S7 1.04721
TXNRD1 thioredoxin reductase 1 1.04721
SHE Src homology 2 domain containing E 1.04647
ACO2 aconitase 2, mitochondrial 1.04611
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.04163
MMP3 matrix metallopeptidase 3 1.04014
TP53 tumor protein p53 1.03752
TBX15 T-box 15 1.03678
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 1.03567
PDX1 pancreatic and duodenal homeobox 1 1.03159
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.03046
CD80 CD80 molecule 1.02858
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 1.02858
ERO1L ERO1-like (S. cerevisiae) 1.02708
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.02708
BDNF brain-derived neurotrophic factor 1.02671
TAGLN2 transgelin 2 1.02336
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 1.02336
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.02114
PLN phospholamban 1.01928
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 1.01928
CCL5 chemokine (C-C motif) ligand 5 1.01587
CEL carboxyl ester lipase 1.01549
CNN3 calponin 3, acidic 1.01549
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.01512
NAMPT nicotinamide phosphoribosyltransferase 1.01474
PRDX6 peroxiredoxin 6 1.01474
IGFBP3 insulin-like growth factor binding protein 3 1.01099