Dengue shock syndrome Gene Set

Dataset GWAS Catalog SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A dengue disease that involves the most severe form of dengue fever, has_material_basis_in Dengue virus [NCBITaxon:12637] with four serotypes (Dengue virus 1, 2, 3 and 4), which are transmitted_by Aedes mosquito bite. The infection has_symptom easy bruising, has_symptom blood spots, has_symptom bleeding gums, and has_symptom nosebleeds. It is accompanied by circulatory collapse, involves hypotension, narrow pulse pressure (less than or equal to 20mm Hg), or frank shock. The shock occurs after two to six days of symptoms, followed by collapse, weak pulse, and blueness around the mouth. (Human Disease Ontology, DOID_0050125)
External Link https://www.ebi.ac.uk/gwas/search?query=Dengue shock syndrome
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Genes

3 genes associated with the Dengue shock syndrome phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
MICB MHC class I polypeptide-related sequence B 0.618573
PLCE1 phospholipase C, epsilon 1 0.560615
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.314454