Degradation of the extracellular matrix Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-1474228
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Genes

89 proteins participating in the Degradation of the extracellular matrix pathway from the Reactome Pathways dataset.

Symbol Name
A2M alpha-2-macroglobulin
ACAN aggrecan
ADAM10 ADAM metallopeptidase domain 10
ADAM15 ADAM metallopeptidase domain 15
ADAM17 ADAM metallopeptidase domain 17
ADAM8 ADAM metallopeptidase domain 8
ADAM9 ADAM metallopeptidase domain 9
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
BCAN brevican
BMP1 bone morphogenetic protein 1
BSG basigin (Ok blood group)
CAPN1 calpain 1, (mu/I) large subunit
CAPNS1 calpain, small subunit 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CD44 CD44 molecule (Indian blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CMA1 chymase 1, mast cell
COL12A1 collagen, type XII, alpha 1
COL13A1 collagen, type XIII, alpha 1
COL14A1 collagen, type XIV, alpha 1
COL15A1 collagen, type XV, alpha 1
COL16A1 collagen, type XVI, alpha 1
COL17A1 collagen, type XVII, alpha 1
COL18A1 collagen, type XVIII, alpha 1
COL19A1 collagen, type XIX, alpha 1
COL23A1 collagen, type XXIII, alpha 1
COL25A1 collagen, type XXV, alpha 1
COL26A1 collagen, type XXVI, alpha 1
COL9A1 collagen, type IX, alpha 1
COL9A2 collagen, type IX, alpha 2
COL9A3 collagen, type IX, alpha 3
CTRB1 chymotrypsinogen B1
CTRB2 chymotrypsinogen B2
CTSB cathepsin B
CTSD cathepsin D
CTSG cathepsin G
CTSK cathepsin K
CTSL cathepsin L
CTSS cathepsin S
CTSV cathepsin V
DCN decorin
ELANE elastase, neutrophil expressed
FURIN furin (paired basic amino acid cleaving enzyme)
HSPG2 heparan sulfate proteoglycan 2
KLK2 kallikrein-related peptidase 2
KLK7 kallikrein-related peptidase 7
KLKB1 kallikrein B, plasma (Fletcher factor) 1
LAMA3 laminin, alpha 3
LAMA5 laminin, alpha 5
LAMB1 laminin, beta 1
LAMB3 laminin, beta 3
LAMC1 laminin, gamma 1 (formerly LAMB2)
LAMC2 laminin, gamma 2
MMP1 matrix metallopeptidase 1
MMP10 matrix metallopeptidase 10
MMP11 matrix metallopeptidase 11
MMP12 matrix metallopeptidase 12
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MMP19 matrix metallopeptidase 19
MMP2 matrix metallopeptidase 2
MMP20 matrix metallopeptidase 20
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MMP25 matrix metallopeptidase 25
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
NCSTN nicastrin
NID1 nidogen 1
PLG plasminogen
PRSS1 protease, serine, 1 (trypsin 1)
PRSS2 protease, serine, 2 (trypsin 2)
PSEN1 presenilin 1
SPP1 secreted phosphoprotein 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TLL1 tolloid-like 1
TLL2 tolloid-like 2
TPSAB1 tryptase alpha/beta 1