Death, Sudden, Cardiac Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D016757
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Genes

158 genes/proteins associated with the disease Death, Sudden, Cardiac from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
TNNT2 troponin T type 2 (cardiac) 2.88009
DSP desmoplakin 2.88009
MYBPC3 myosin binding protein C, cardiac 2.88009
LMNA lamin A/C 2.88009
TMEM43 transmembrane protein 43 2.88009
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.114
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.99988
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.94753
PRL prolactin 1.89042
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.88327
FOS FBJ murine osteosarcoma viral oncogene homolog 1.81885
TNF tumor necrosis factor 1.76072
CAT catalase 1.74802
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.71441
NPPA natriuretic peptide A 1.68804
BCL2 B-cell CLL/lymphoma 2 1.68464
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.68274
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.68041
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.66382
MAPK1 mitogen-activated protein kinase 1 1.6278
IL6 interleukin 6 1.62401
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.60874
DRD1 dopamine receptor D1 1.59451
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.58818
MAPK3 mitogen-activated protein kinase 3 1.56435
DRD2 dopamine receptor D2 1.53456
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.52938
BDNF brain-derived neurotrophic factor 1.51405
BAX BCL2-associated X protein 1.51255
SOD1 superoxide dismutase 1, soluble 1.50953
INHBE inhibin, beta E 1.50273
CRH corticotropin releasing hormone 1.50018
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.49736
NUPR1 nuclear protein, transcriptional regulator, 1 1.4753
C10ORF10 chromosome 10 open reading frame 10 1.47374
FNDC4 fibronectin type III domain containing 4 1.47374
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.47012
TH tyrosine hydroxylase 1.46067
REN renin 1.42642
EGR1 early growth response 1 1.41721
FAS Fas cell surface death receptor 1.41559
JUN jun proto-oncogene 1.40897
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.40623
INS insulin 1.40429
PENK proenkephalin 1.40204
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.40008
MAP2K1 mitogen-activated protein kinase kinase 1 1.39841
ADRB1 adrenoceptor beta 1 1.39422
MAP2K2 mitogen-activated protein kinase kinase 2 1.38469
NPY neuropeptide Y 1.3682
MAOA monoamine oxidase A 1.36275
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.35531
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.35531
IL1B interleukin 1, beta 1.3484
TGFB1 transforming growth factor, beta 1 1.3484
NOS2 nitric oxide synthase 2, inducible 1.34343
DRD3 dopamine receptor D3 1.33346
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.32876
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.32876
PRKCD protein kinase C, delta 1.31776
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.31297
GFAP glial fibrillary acidic protein 1.31297
TAGLN transgelin 1.31089
AVP arginine vasopressin 1.29996
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.2818
DDIT3 DNA-damage-inducible transcript 3 1.28149
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.27905
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.27689
PRKCE protein kinase C, epsilon 1.27502
GSK3B glycogen synthase kinase 3 beta 1.27409
MMP9 matrix metallopeptidase 9 1.26856
MMP2 matrix metallopeptidase 2 1.26421
ARC activity-regulated cytoskeleton-associated protein 1.25214
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.24905
MAPK8 mitogen-activated protein kinase 8 1.24781
DUSP1 dual specificity phosphatase 1 1.23868
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.23837
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.23424
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.23011
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.22853
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.22016
DLAT dihydrolipoamide S-acetyltransferase 1.21599
SOD2 superoxide dismutase 2, mitochondrial 1.20361
IL10 interleukin 10 1.20361
GSTP1 glutathione S-transferase pi 1 1.20295
PHYH phytanoyl-CoA 2-hydroxylase 1.19999
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.19802
CREM cAMP responsive element modulator 1.19802
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.1977
EDN1 endothelin 1 1.18587
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.18424
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.18193
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.18193
HPCA hippocalcin 1.17993
MPO myeloperoxidase 1.17959
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.17563
MBP myelin basic protein 1.1753
CREB1 cAMP responsive element binding protein 1 1.17366
ADRB2 adrenoceptor beta 2, surface 1.17134
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.169
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.16567
PRKCA protein kinase C, alpha 1.15967
EGR2 early growth response 2 1.15831
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.15797
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.15458
HOMER1 homer scaffolding protein 1 1.15324
JUNB jun B proto-oncogene 1.14268
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.13997
RGS2 regulator of G-protein signaling 2 1.13827
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.13586
PRKCB protein kinase C, beta 1.13415
PKM pyruvate kinase, muscle 1.13415
VIM vimentin 1.1294
CLU clusterin 1.1294
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.12805
FASLG Fas ligand (TNF superfamily, member 6) 1.12703
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.12495
SREBF1 sterol regulatory element binding transcription factor 1 1.12151
FABP1 fatty acid binding protein 1, liver 1.11945
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.11741
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.11707
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.11431
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.11396
CCND1 cyclin D1 1.10493
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.10317
BCL2L1 BCL2-like 1 1.10246
CYP3A cytochrome P450, family 3, subfamily A 1.09963
FOSL2 FOS-like antigen 2 1.08868
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.07625
TP53 tumor protein p53 1.07482
IFNG interferon, gamma 1.06734
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 1.06698
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.06661
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.06625
ADRA1B adrenoceptor alpha 1B 1.0637
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.06225
IGF1 insulin-like growth factor 1 (somatomedin C) 1.0608
DUSP8 dual specificity phosphatase 8 1.05793
SCN5A sodium channel, voltage gated, type V alpha subunit 1.05423
GSK3A glycogen synthase kinase 3 alpha 1.05423
HPN hepsin 1.05052
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.04684
FOXO1 forkhead box O1 1.04465
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 1.04239
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 1.04163
EGFR epidermal growth factor receptor 1.03789
NOS3 nitric oxide synthase 3 (endothelial cell) 1.03789
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.03159
PVALB parvalbumin 1.03009
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.02634
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.02485
GRM1 glutamate receptor, metabotropic 1 1.02262
RYR2 ryanodine receptor 2 (cardiac) 1.02262
ADRA1D adrenoceptor alpha 1D 1.02003
GNAS GNAS complex locus 1.01852
NGF nerve growth factor (beta polypeptide) 1.01474
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.01474
HSPA8 heat shock 70kDa protein 8 1.01062