De novo purine biosynthesis Gene Set

Dataset PANTHER Pathways
Category structural or functional annotations
Type pathway
Description The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate. (Gene Ontology, GO_0006189)
External Link http://www.pantherdb.org/pathway/pathDetail.do?clsAccession=P02738
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Genes

23 proteins participating in the De novo purine biosynthesis pathway from the PANTHER Pathways dataset.

Symbol Name
ADSL adenylosuccinate lyase
ADSS adenylosuccinate synthase
ADSSL1 adenylosuccinate synthase like 1
AK1 adenylate kinase 1
AK2 adenylate kinase 2
AK3 adenylate kinase 3
AK5 adenylate kinase 5
AK8 adenylate kinase 8
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GMPS guanine monphosphate synthase
GUK1 guanylate kinase 1
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
NME1 NME/NM23 nucleoside diphosphate kinase 1
NME3 NME/NM23 nucleoside diphosphate kinase 3
NME4 NME/NM23 nucleoside diphosphate kinase 4
NME5 NME/NM23 family member 5
NME6 NME/NM23 nucleoside diphosphate kinase 6
NME7 NME/NM23 family member 7
PPAT phosphoribosyl pyrophosphate amidotransferase
RRM1 ribonucleotide reductase M1
RRM2 ribonucleotide reductase M2
RRM2B ribonucleotide reductase M2 B (TP53 inducible)