DNA synthesome complex Gene Set

Dataset CORUM Protein Complexes
Category structural or functional annotations
Type protein complex
Description A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins. (Gene Ontology, GO_0030894)
External Link http://mips.helmholtz-muenchen.de/genre/proj/corum/complexdetails.html?id=1001
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Genes

11 proteins in the DNA synthesome complex protein complex from the CORUM Protein Complexes dataset.

Symbol Name
LIG1 ligase I, DNA, ATP-dependent
PCNA proliferating cell nuclear antigen
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLD2 polymerase (DNA directed), delta 2, accessory subunit
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRIM2 primase, DNA, polypeptide 2 (58kDa)
TOP1 topoisomerase (DNA) I