DNA replication Gene Set

Dataset PANTHER Pathways
Category structural or functional annotations
Type pathway
Description The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA. (Gene Ontology, GO_0006260)
External Link http://www.pantherdb.org/pathway/pathDetail.do?clsAccession=P00017
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Genes

18 proteins participating in the DNA replication pathway from the PANTHER Pathways dataset.

Symbol Name
DNA2 DNA replication helicase/nuclease 2
H3F3C H3 histone, family 3C
HIST3H3 histone cluster 3, H3
PCNA proliferating cell nuclear antigen
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLD2 polymerase (DNA directed), delta 2, accessory subunit
PRIM1 primase, DNA, polypeptide 1 (49kDa)
RFC1 replication factor C (activator 1) 1, 145kDa
RFC2 replication factor C (activator 1) 2, 40kDa
RFC3 replication factor C (activator 1) 3, 38kDa
RFC4 replication factor C (activator 1) 4, 37kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
RNASEH1 ribonuclease H1
RPA2 replication protein A2, 32kDa
TOP1 topoisomerase (DNA) I
TOP2A topoisomerase (DNA) II alpha 170kDa
TOP2B topoisomerase (DNA) II beta 180kDa