DNA replication initiation Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
Description The process in which DNA-dependent DNA replication is started; this involves the separation of a stretch of the DNA double helix, the recruitment of DNA polymerases and the initiation of polymerase action. (Gene Ontology, GO_0006270)
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-68952
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Genes

6 proteins participating in the DNA replication initiation pathway from the Reactome Pathways dataset.

Symbol Name
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRIM2 primase, DNA, polypeptide 2 (58kDa)