DNA Damage Response (only ATM dependent)(Homo sapiens) Gene Set

Dataset Wikipathways Pathways
Category structural or functional annotations
Type pathway
External Link http://www.wikipathways.org/instance/WP710_r79974
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Genes

93 proteins participating in the DNA Damage Response (only ATM dependent)(Homo sapiens) pathway from the Wikipathways Pathways dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
APC adenomatous polyposis coli
ATM ATM serine/threonine kinase
AXIN1 axin 1
BAD BCL2-associated agonist of cell death
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL6 B-cell CLL/lymphoma 6
BIK BCL2-interacting killer (apoptosis-inducing)
CAT catalase
CCND1 cyclin D1
CCND2 cyclin D2
CCND3 cyclin D3
CCNG2 cyclin G2
CDC42 cell division cycle 42
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DVL1 dishevelled segment polarity protein 1
DVL2 dishevelled segment polarity protein 2
DVL3 dishevelled segment polarity protein 3
ERBB2 erb-b2 receptor tyrosine kinase 2
FASLG Fas ligand (TNF superfamily, member 6)
FOSL1 FOS-like antigen 1
FOXO3 forkhead box O3
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
G6PC glucose-6-phosphatase, catalytic subunit
GRB2 growth factor receptor-bound protein 2
GSK3B glycogen synthase kinase 3 beta
HMGB1 high mobility group box 1
INSR insulin receptor
IRS1 insulin receptor substrate 1
JUN jun proto-oncogene
LDLR low density lipoprotein receptor
LOC100129518 uncharacterized LOC100129518
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIR3190 microRNA 3190
MIR3191 microRNA 3191
MLKL mixed lineage kinase domain-like
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PLAU plasminogen activator, urokinase
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PTEN phosphatase and tensin homolog
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RBL2 retinoblastoma-like 2
RHOA ras homolog family member A
SCP2 sterol carrier protein 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SOD2 superoxide dismutase 2, mitochondrial
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
TGFB1 transforming growth factor, beta 1
TP53 tumor protein p53
TP73 tumor protein p73
WNT1 wingless-type MMTV integration site family, member 1
WNT10A wingless-type MMTV integration site family, member 10A
WNT10B wingless-type MMTV integration site family, member 10B
WNT11 wingless-type MMTV integration site family, member 11
WNT16 wingless-type MMTV integration site family, member 16
WNT2 wingless-type MMTV integration site family member 2
WNT2B wingless-type MMTV integration site family, member 2B
WNT3 wingless-type MMTV integration site family, member 3
WNT3A wingless-type MMTV integration site family, member 3A
WNT4 wingless-type MMTV integration site family, member 4
WNT5A wingless-type MMTV integration site family, member 5A
WNT5B wingless-type MMTV integration site family, member 5B
WNT6 wingless-type MMTV integration site family, member 6
WNT7A wingless-type MMTV integration site family, member 7A
WNT7B wingless-type MMTV integration site family, member 7B