DNA Damage Response(Homo sapiens) Gene Set

Dataset Wikipathways Pathways
Category structural or functional annotations
Type pathway
External Link http://www.wikipathways.org/instance/WP707_r82937
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Genes

69 proteins participating in the DNA Damage Response(Homo sapiens) pathway from the Wikipathways Pathways dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
APAF1 apoptotic peptidase activating factor 1
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
ATRIP ATR interacting protein
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BID BH3 interacting domain death agonist
BRCA1 breast cancer 1, early onset
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCNB1 cyclin B1
CCNB2 cyclin B2
CCNB3 cyclin B3
CCND1 cyclin D1
CCND2 cyclin D2
CCND3 cyclin D3
CCNE1 cyclin E1
CCNE2 cyclin E2
CDC25A cell division cycle 25A
CDC25C cell division cycle 25C
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDK5 cyclin-dependent kinase 5
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CREB1 cAMP responsive element binding protein 1
CYCS cytochrome c, somatic
DDB2 damage-specific DNA binding protein 2, 48kDa
E2F1 E2F transcription factor 1
FANCD2 Fanconi anemia, complementation group D2
FAS Fas cell surface death receptor
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GADD45G growth arrest and DNA-damage-inducible, gamma
H2AFX H2A histone family, member X
HUS1B HUS1 checkpoint homolog b (S. pombe)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIR3190 microRNA 3190
MIR3191 microRNA 3191
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NBN nibrin
PIDD1 p53-induced death domain protein 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
RAD1 RAD1 checkpoint DNA exonuclease
RAD17 RAD17 homolog (S. pombe)
RAD50 RAD50 homolog (S. cerevisiae)
RAD51 RAD51 recombinase
RAD52 RAD52 homolog (S. cerevisiae)
RAD9A RAD9 homolog A (S. pombe)
RB1 retinoblastoma 1
RFC1 replication factor C (activator 1) 1, 145kDa
RPA2 replication protein A2, 32kDa
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
SESN1 sestrin 1
SFN stratifin
SMC1A structural maintenance of chromosomes 1A
TLK1 tousled-like kinase 1
TLK2 tousled-like kinase 2
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TP53 tumor protein p53
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1