DNA Damage/Telomere Stress Induced Senescence Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-2559586
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Genes

58 proteins participating in the DNA Damage/Telomere Stress Induced Senescence pathway from the Reactome Pathways dataset.

Symbol Name
ACD adrenocortical dysplasia homolog (mouse)
ASF1A anti-silencing function 1A histone chaperone
ATM ATM serine/threonine kinase
CABIN1 calcineurin binding protein 1
CCNA1 cyclin A1
CCNA2 cyclin A2
CCNE1 cyclin E1
CCNE2 cyclin E2
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
EP400 E1A binding protein p400
H1F0 H1 histone family, member 0
H2AFB1 H2A histone family, member B1
H2AFX H2A histone family, member X
H2AFZ H2A histone family, member Z
H2BFS H2B histone family, member S (pseudogene)
HIRA histone cell cycle regulator
HIST1H1A histone cluster 1, H1a
HIST1H1B histone cluster 1, H1b
HIST1H1C histone cluster 1, H1c
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2AB histone cluster 1, H2ab
HIST1H2AC histone cluster 1, H2ac
HIST1H2AD histone cluster 1, H2ad
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BA histone cluster 1, H2ba
HIST1H2BB histone cluster 1, H2bb
HIST1H2BC histone cluster 1, H2bc
HIST1H2BD histone cluster 1, H2bd
HIST1H2BH histone cluster 1, H2bh
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BK histone cluster 1, H2bk
HIST1H2BL histone cluster 1, H2bl
HIST1H2BM histone cluster 1, H2bm
HIST1H2BN histone cluster 1, H2bn
HIST1H2BO histone cluster 1, H2bo
HIST1H4A histone cluster 1, H4a
HIST2H2AA3 histone cluster 2, H2aa3
HIST2H2AC histone cluster 2, H2ac
HIST2H2BE histone cluster 2, H2be
HIST3H2BB histone cluster 3, H2bb
HIST3H3 histone cluster 3, H3
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2
LMNB1 lamin B1
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
NBN nibrin
POT1 protection of telomeres 1
RAD50 RAD50 homolog (S. cerevisiae)
RB1 retinoblastoma 1
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERF2 telomeric repeat binding factor 2
TERF2IP telomeric repeat binding factor 2, interacting protein
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TP53 tumor protein p53
UBN1 ubinuclein 1