Cystic Fibrosis_Pancreas_GSE769 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE769
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Genes

600 genes differentially expressed during Cystic Fibrosis_Pancreas_GSE769 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
ADSS adenylosuccinate synthase 5.12632
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 4.46259
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 4.44878
IPP intracisternal A particle-promoted polypeptide 4.03452
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 4.00592
RPIA ribose 5-phosphate isomerase A 3.94568
NHLH1 nescient helix loop helix 1 3.90868
TBRG1 transforming growth factor beta regulator 1 3.55319
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 3.43406
ZC3HC1 zinc finger, C3HC-type containing 1 3.40522
RSL1D1 ribosomal L1 domain containing 1 3.11086
EIF4A3 eukaryotic translation initiation factor 4A3 3.09584
HAX1 HCLS1 associated protein X-1 3.08596
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 3.04806
MYD88 myeloid differentiation primary response 88 3.03992
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 3.03674
EGFR epidermal growth factor receptor 3.03427
NME6 NME/NM23 nucleoside diphosphate kinase 6 2.97419
LRRC59 leucine rich repeat containing 59 2.9549
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 2.92677
MLX MLX, MAX dimerization protein 2.78817
LAMA5 laminin, alpha 5 2.7514
ZNHIT1 zinc finger, HIT-type containing 1 2.74397
CHUK conserved helix-loop-helix ubiquitous kinase 2.73396
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 2.72908
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.68733
RBM17 RNA binding motif protein 17 2.65487
ANAPC16 anaphase promoting complex subunit 16 2.64785
LSG1 large 60S subunit nuclear export GTPase 1 2.61444
SNIP1 Smad nuclear interacting protein 1 2.59348
IGF1 insulin-like growth factor 1 (somatomedin C) 2.56695
SFPQ splicing factor proline/glutamine-rich 2.51695
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 2.51332
TMEM176B transmembrane protein 176B 2.50152
SLC35E1 solute carrier family 35, member E1 2.49202
BECN1 beclin 1, autophagy related 2.47286
PRADC1 protease-associated domain containing 1 2.45707
PTPN2 protein tyrosine phosphatase, non-receptor type 2 2.43415
SCAMP3 secretory carrier membrane protein 3 2.42852
TBK1 TANK-binding kinase 1 2.39064
SRPR signal recognition particle receptor (docking protein) 2.37993
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 2.35559
TBC1D15 TBC1 domain family, member 15 2.35351
PLXNB2 plexin B2 2.35096
LLGL2 lethal giant larvae homolog 2 (Drosophila) 2.32807
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 2.27095
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 2.26151
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) 2.23109
HSPA4 heat shock 70kDa protein 4 2.22768
VRK3 vaccinia related kinase 3 2.2238
QDPR quinoid dihydropteridine reductase 2.21355
METTL1 methyltransferase like 1 2.20062
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa 2.18684
IFT20 intraflagellar transport 20 2.18301
RNASEK ribonuclease, RNase K 2.18115
GJA8 gap junction protein, alpha 8, 50kDa 2.17046
ETF1 eukaryotic translation termination factor 1 2.16171
PCYOX1 prenylcysteine oxidase 1 2.14516
CUL1 cullin 1 2.14407
TMEM179B transmembrane protein 179B 2.14079
MYPOP Myb-related transcription factor, partner of profilin 2.11676
TM2D2 TM2 domain containing 2 2.10497
DOCK5 dedicator of cytokinesis 5 2.07801
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 2.07113
LARP4B La ribonucleoprotein domain family, member 4B 2.06474
WSB2 WD repeat and SOCS box containing 2 2.0613
F11R F11 receptor 2.03384
SF3A3 splicing factor 3a, subunit 3, 60kDa 2.0171
SURF1 surfeit 1 1.99549
GTF2B general transcription factor IIB 1.98606
TRABD TraB domain containing 1.97739
ARNTL aryl hydrocarbon receptor nuclear translocator-like 1.97207
UNC50 unc-50 homolog (C. elegans) 1.96933
BYSL bystin-like 1.92133
SLC39A9 solute carrier family 39, member 9 1.8916
RFC3 replication factor C (activator 1) 3, 38kDa 1.88957
ANG angiogenin, ribonuclease, RNase A family, 5 1.8839
HOXC9 homeobox C9 1.8711
LY6E lymphocyte antigen 6 complex, locus E 1.86003
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 1.8486
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 1.84727
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H') 1.83813
SEC11A SEC11 homolog A (S. cerevisiae) 1.83585
SRSF10 serine/arginine-rich splicing factor 10 1.83376
TMEM141 transmembrane protein 141 1.83161
TXNRD1 thioredoxin reductase 1 1.82335
HAP1 huntingtin-associated protein 1 1.81216
MAT2A methionine adenosyltransferase II, alpha 1.80582
PGLS 6-phosphogluconolactonase 1.79663
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 1.78532
DCAF11 DDB1 and CUL4 associated factor 11 1.78196
DUS1L dihydrouridine synthase 1-like (S. cerevisiae) 1.77839
PRKCSH protein kinase C substrate 80K-H 1.77471
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 1.74289
APCS amyloid P component, serum 1.74288
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 1.73306
VMP1 vacuole membrane protein 1 1.73179
PPP4R2 protein phosphatase 4, regulatory subunit 2 1.73047
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 1.7239
RAB10 RAB10, member RAS oncogene family 1.71181
BIRC2 baculoviral IAP repeat containing 2 1.69931
ETFDH electron-transferring-flavoprotein dehydrogenase 1.69756
TMEM131 transmembrane protein 131 1.68067
RPS5 ribosomal protein S5 1.67465
IDS iduronate 2-sulfatase 1.65094
C19ORF70 chromosome 19 open reading frame 70 1.63953
FAM83G family with sequence similarity 83, member G 1.63297
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 1.63196
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 1.63067
GORASP2 golgi reassembly stacking protein 2, 55kDa 1.63032
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 1.62561
RPS7 ribosomal protein S7 1.6236
GLO1 glyoxalase I 1.61949
CPT2 carnitine palmitoyltransferase 2 1.60397
MANF mesencephalic astrocyte-derived neurotrophic factor 1.59549
PRAP1 proline-rich acidic protein 1 1.57678
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 1.57424
FAM192A family with sequence similarity 192, member A 1.5693
GCK glucokinase (hexokinase 4) 1.56754
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 1.56619
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22 1.56601
MRPS18A mitochondrial ribosomal protein S18A 1.55178
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 1.55164
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 1.53776
NOP10 NOP10 ribonucleoprotein 1.52788
TSKU tsukushi, small leucine rich proteoglycan 1.52705
LIFR leukemia inhibitory factor receptor alpha 1.52308
PEX6 peroxisomal biogenesis factor 6 1.50842
IVNS1ABP influenza virus NS1A binding protein 1.50587
DAZAP2 DAZ associated protein 2 1.50568
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic) 1.50538
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) 1.50524
RUVBL2 RuvB-like AAA ATPase 2 1.49869
PPP6C protein phosphatase 6, catalytic subunit 1.49821
PNO1 partner of NOB1 homolog (S. cerevisiae) 1.49704
GALNT4 polypeptide N-acetylgalactosaminyltransferase 4 1.48714
UMPS uridine monophosphate synthetase 1.48297
COQ9 coenzyme Q9 1.4702
LMNA lamin A/C 1.46611
RAB11A RAB11A, member RAS oncogene family 1.46382
PPIB peptidylprolyl isomerase B (cyclophilin B) 1.46107
TOR1AIP2 torsin A interacting protein 2 1.45345
CYHR1 cysteine/histidine-rich 1 1.44576
COLGALT1 collagen beta(1-O)galactosyltransferase 1 1.44458
MYDGF myeloid-derived growth factor 1.43422
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 1.42345
EPCAM epithelial cell adhesion molecule 1.42287
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 1.42273
CENPI centromere protein I 1.4206
NDFIP2 Nedd4 family interacting protein 2 1.41958
USP9X ubiquitin specific peptidase 9, X-linked 1.4176
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa 1.41249
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 1.4064
UBE2N ubiquitin-conjugating enzyme E2N 1.40529
MNAT1 MNAT CDK-activating kinase assembly factor 1 1.40249
NOP16 NOP16 nucleolar protein 1.3976
UBA1 ubiquitin-like modifier activating enzyme 1 1.39474
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 1.37652
S100A3 S100 calcium binding protein A3 1.37605
PARD6G par-6 family cell polarity regulator gamma 1.37133
WARS tryptophanyl-tRNA synthetase 1.36941
WDR45 WD repeat domain 45 1.3588
PEX2 peroxisomal biogenesis factor 2 1.35499
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 1.34585
ATPIF1 ATPase inhibitory factor 1 1.34556
JAK2 Janus kinase 2 1.34246
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 1.34179
RAB4B RAB4B, member RAS oncogene family 1.33538
CHERP calcium homeostasis endoplasmic reticulum protein 1.33467
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 1.33449
SHFM1 split hand/foot malformation (ectrodactyly) type 1 1.33291
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 1.32638
CMIP c-Maf inducing protein 1.32139
DERL1 derlin 1 1.31478
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 1.31243
CDC42SE2 CDC42 small effector 2 1.30858
LEMD2 LEM domain containing 2 1.30274
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 1.29771
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 1.29582
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 1.29337
TNPO2 transportin 2 1.28841
RAB11FIP5 RAB11 family interacting protein 5 (class I) 1.28245
UBAC2 UBA domain containing 2 1.282
TMEM165 transmembrane protein 165 1.27306
AP1AR adaptor-related protein complex 1 associated regulatory protein 1.27249
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 1.27115
MRPL20 mitochondrial ribosomal protein L20 1.27018
BZW2 basic leucine zipper and W2 domains 2 1.26928
CSNK2A2 casein kinase 2, alpha prime polypeptide 1.26918
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 1.26732
C17ORF49 chromosome 17 open reading frame 49 1.26573
TYRO3 TYRO3 protein tyrosine kinase 1.264
VARS valyl-tRNA synthetase 1.26061
RPS25 ribosomal protein S25 1.25979
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 1.25582
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 1.25218
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 1.25164
CCNE1 cyclin E1 1.25099
SEC23B Sec23 homolog B (S. cerevisiae) 1.24932
USP6NL USP6 N-terminal like 1.24802
DDB1 damage-specific DNA binding protein 1, 127kDa 1.24588
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 1.24092
AZGP1 alpha-2-glycoprotein 1, zinc-binding 1.23748
ICT1 immature colon carcinoma transcript 1 1.23108
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 1.22637
PROM1 prominin 1 1.22614
ITM2C integral membrane protein 2C 1.2235
CHMP6 charged multivesicular body protein 6 1.22318
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 1.22098
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 1.2205
REG3A regenerating islet-derived 3 alpha 1.21896
ARL2BP ADP-ribosylation factor-like 2 binding protein 1.21585
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 1.21234
NACA nascent polypeptide-associated complex alpha subunit 1.21215
FICD FIC domain containing 1.20214
LENG9 leukocyte receptor cluster (LRC) member 9 1.20073
GOLGA4 golgin A4 1.19643
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 1.19332
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 1.1902
INO80C INO80 complex subunit C 1.18974
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.18418
NINJ1 ninjurin 1 1.17624
COL9A1 collagen, type IX, alpha 1 1.17149
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 1.16981
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 1.1668
HBS1L HBS1-like translational GTPase 1.16296
LPP LIM domain containing preferred translocation partner in lipoma 1.16221
CTSV cathepsin V 1.15994
FERMT2 fermitin family member 2 1.15714
RCL1 RNA terminal phosphate cyclase-like 1 1.15667
SURF4 surfeit 4 1.15086
NAE1 NEDD8 activating enzyme E1 subunit 1 1.13927
MPG N-methylpurine-DNA glycosylase 1.13266
CINP cyclin-dependent kinase 2 interacting protein 1.12755
B3GALT6 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 1.12706
ACTG1 actin gamma 1 1.12706
MAP3K3 mitogen-activated protein kinase kinase kinase 3 1.12196
HDAC7 histone deacetylase 7 1.11774
RPL10A ribosomal protein L10a 1.11749
SLMAP sarcolemma associated protein 1.11611
SOCS3 suppressor of cytokine signaling 3 1.11539
EPN1 epsin 1 1.10905
NIT1 nitrilase 1 1.10816
RNASEH2C ribonuclease H2, subunit C 1.10482
TMC6 transmembrane channel-like 6 1.10007
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 1.09619
NOP58 NOP58 ribonucleoprotein 1.08825
USO1 USO1 vesicle transport factor 1.08615
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 1.08524
MYO1D myosin ID 1.08499
IGF2 insulin-like growth factor 2 1.0763
ACADL acyl-CoA dehydrogenase, long chain 1.07527
FGL2 fibrinogen-like 2 1.07484
MYO10 myosin X 1.07328
TMOD3 tropomodulin 3 (ubiquitous) 1.07277
SRA1 steroid receptor RNA activator 1 1.0717
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B 1.07102
RARS arginyl-tRNA synthetase 1.07009
HM13 histocompatibility (minor) 13 1.06635
CSN3 casein kappa 1.06449
MTNR1A melatonin receptor 1A 1.06063
PSME4 proteasome (prosome, macropain) activator subunit 4 1.05668
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 1.05476
PARL presenilin associated, rhomboid-like 1.05149
EIF5A eukaryotic translation initiation factor 5A 1.05049
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 1.04952
BMP8A bone morphogenetic protein 8a 1.04442
USP48 ubiquitin specific peptidase 48 1.04298
REG3G regenerating islet-derived 3 gamma 1.04226
ORC4 origin recognition complex, subunit 4 1.03914
ARMC10 armadillo repeat containing 10 1.03591
FTO fat mass and obesity associated 1.03582
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 1.03261
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 1.03012
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2 1.02815
ONECUT1 one cut homeobox 1 1.02751
ZNF35 zinc finger protein 35 1.02633
JTB jumping translocation breakpoint 1.02563
CPOX coproporphyrinogen oxidase 1.02141
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 1.0214
SEP15 15 kDa selenoprotein 1.02091
TST thiosulfate sulfurtransferase (rhodanese) 1.01799
GTF2A2 general transcription factor IIA, 2, 12kDa 1.01501
ZNF148 zinc finger protein 148 1.01379
TPRG1L tumor protein p63 regulated 1-like 1.01056
PPP6R3 protein phosphatase 6, regulatory subunit 3 1.00948
FOXP2 forkhead box P2 1.00886
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 1.00578
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 1.0052
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 1.00414
PPP4C protein phosphatase 4, catalytic subunit 1.00242
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 0.995882
LDHAL6A lactate dehydrogenase A-like 6A 0.995129
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.991932
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 0.990086
RNF20 ring finger protein 20, E3 ubiquitin protein ligase 0.989952
SAT1 spermidine/spermine N1-acetyltransferase 1 0.987716
SBDS Shwachman-Bodian-Diamond syndrome 0.985738
ITCH itchy E3 ubiquitin protein ligase 0.985096
NMI N-myc (and STAT) interactor 0.982358

decreased expression

Symbol Name Standardized Value
SRPRB signal recognition particle receptor, B subunit -4.68146
RNF149 ring finger protein 149 -3.5635
SOD2 superoxide dismutase 2, mitochondrial -3.51991
YBX1 Y box binding protein 1 -2.88097
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -2.81282
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -2.74656
JARID2 jumonji, AT rich interactive domain 2 -2.65759
CCDC94 coiled-coil domain containing 94 -2.59077
PRKCD protein kinase C, delta -2.5904
MATK megakaryocyte-associated tyrosine kinase -2.58045
C2ORF49 chromosome 2 open reading frame 49 -2.56411
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 -2.51235
WDR75 WD repeat domain 75 -2.51218
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) -2.45607
MRPL48 mitochondrial ribosomal protein L48 -2.40891
SPOP speckle-type POZ protein -2.40852
GBX2 gastrulation brain homeobox 2 -2.40621
FKBP1A FK506 binding protein 1A, 12kDa -2.39376
CAT catalase -2.3584
APIP APAF1 interacting protein -2.35368
SHD Src homology 2 domain containing transforming protein D -2.34909
SLC35B1 solute carrier family 35, member B1 -2.31614
SF3B3 splicing factor 3b, subunit 3, 130kDa -2.30188
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 -2.24239
CADPS2 Ca++-dependent secretion activator 2 -2.22454
HDGF hepatoma-derived growth factor -2.19471
DLG3 discs, large homolog 3 (Drosophila) -2.12352
FSTL1 follistatin-like 1 -2.11564
RSU1 Ras suppressor protein 1 -2.11284
TTR transthyretin -2.09741
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -2.08884
NFIX nuclear factor I/X (CCAAT-binding transcription factor) -2.05235
FIBP fibroblast growth factor (acidic) intracellular binding protein -2.03879
C9ORF72 chromosome 9 open reading frame 72 -2.02352
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 -2.01449
MIEN1 migration and invasion enhancer 1 -2.00333
KLC1 kinesin light chain 1 -1.99827
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -1.97803
STOML2 stomatin (EPB72)-like 2 -1.94982
MRPL40 mitochondrial ribosomal protein L40 -1.94788
ZMYM4 zinc finger, MYM-type 4 -1.93636
CYC1 cytochrome c-1 -1.92475
KCNK1 potassium channel, two pore domain subfamily K, member 1 -1.91837
TNNI2 troponin I type 2 (skeletal, fast) -1.91132
GDI2 GDP dissociation inhibitor 2 -1.90208
UBL3 ubiquitin-like 3 -1.8889
TLN1 talin 1 -1.84855
REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae) -1.81527
MYH7 myosin, heavy chain 7, cardiac muscle, beta -1.79613
TMEM30A transmembrane protein 30A -1.78168
TMPO thymopoietin -1.77836
MAPK8 mitogen-activated protein kinase 8 -1.76768
ORC1 origin recognition complex, subunit 1 -1.75625
CYTIP cytohesin 1 interacting protein -1.75185
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 -1.74579
FAM13B family with sequence similarity 13, member B -1.74255
TTC17 tetratricopeptide repeat domain 17 -1.73226
DEF8 differentially expressed in FDCP 8 homolog (mouse) -1.71968
TIMP3 TIMP metallopeptidase inhibitor 3 -1.71864
SCOC short coiled-coil protein -1.68807
TM7SF2 transmembrane 7 superfamily member 2 -1.68628
DHRS7 dehydrogenase/reductase (SDR family) member 7 -1.66701
SIAH2 siah E3 ubiquitin protein ligase 2 -1.666
CSDE1 cold shock domain containing E1, RNA-binding -1.66509
PTH parathyroid hormone -1.66271
DUSP12 dual specificity phosphatase 12 -1.64962
EPN2 epsin 2 -1.63405
PQLC1 PQ loop repeat containing 1 -1.63232
UBE2O ubiquitin-conjugating enzyme E2O -1.6204
ODC1 ornithine decarboxylase 1 -1.60476
PCSK6 proprotein convertase subtilisin/kexin type 6 -1.59555
SELP selectin P (granule membrane protein 140kDa, antigen CD62) -1.59382
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 -1.58586
BIRC6 baculoviral IAP repeat containing 6 -1.56702
NR1D1 nuclear receptor subfamily 1, group D, member 1 -1.56544
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 -1.56382
SMAD6 SMAD family member 6 -1.56195
MPP1 membrane protein, palmitoylated 1, 55kDa -1.54516
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) -1.54353
FMO5 flavin containing monooxygenase 5 -1.53914
BMP7 bone morphogenetic protein 7 -1.52938
EVL Enah/Vasp-like -1.52782
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa -1.51689
GCSH glycine cleavage system protein H (aminomethyl carrier) -1.50595
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -1.49433
RRAGC Ras-related GTP binding C -1.49164
SQSTM1 sequestosome 1 -1.49036
NFYC nuclear transcription factor Y, gamma -1.48327
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) -1.48263
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -1.47948
GAMT guanidinoacetate N-methyltransferase -1.47434
HADH hydroxyacyl-CoA dehydrogenase -1.46854
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa -1.46039
HAUS3 HAUS augmin-like complex, subunit 3 -1.45823
CSF1 colony stimulating factor 1 (macrophage) -1.45415
TWSG1 twisted gastrulation BMP signaling modulator 1 -1.45095
ENPEP glutamyl aminopeptidase (aminopeptidase A) -1.4301
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 -1.42896
UPK3B uroplakin 3B -1.42462
CTSB cathepsin B -1.42288
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -1.42214
PPAP2B phosphatidic acid phosphatase type 2B -1.40381
APP amyloid beta (A4) precursor protein -1.40121
LUM lumican -1.40047
APH1A APH1A gamma secretase subunit -1.39079
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) -1.38837
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 -1.38435
APOA1BP apolipoprotein A-I binding protein -1.38212
C1ORF158 chromosome 1 open reading frame 158 -1.3811
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2 -1.38076
SNX2 sorting nexin 2 -1.37599
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -1.37582
FOXM1 forkhead box M1 -1.37532
FAM46A family with sequence similarity 46, member A -1.37119
NUDT16L1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 -1.36778
SFR1 SWI5-dependent recombination repair 1 -1.36126
LAMP1 lysosomal-associated membrane protein 1 -1.35326
SND1 staphylococcal nuclease and tudor domain containing 1 -1.35069
CSAD cysteine sulfinic acid decarboxylase -1.34737
RBL1 retinoblastoma-like 1 -1.3405
FABP7 fatty acid binding protein 7, brain -1.34005
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide -1.33602
AGTRAP angiotensin II receptor-associated protein -1.32661
ATF3 activating transcription factor 3 -1.32551
DGUOK deoxyguanosine kinase -1.32124
WDR5 WD repeat domain 5 -1.3146
NPC1 Niemann-Pick disease, type C1 -1.31382
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -1.31272
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 -1.29288
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -1.2902
RRP1B ribosomal RNA processing 1B -1.28941
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -1.28439
AMZ2 archaelysin family metallopeptidase 2 -1.27909
THUMPD3 THUMP domain containing 3 -1.27856
BGN biglycan -1.27592
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa -1.27546
ANKRD11 ankyrin repeat domain 11 -1.27134
ALAD aminolevulinate dehydratase -1.26328
PARP16 poly (ADP-ribose) polymerase family, member 16 -1.24967
WISP2 WNT1 inducible signaling pathway protein 2 -1.24966
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -1.24954
GAS6 growth arrest-specific 6 -1.24454
IARS isoleucyl-tRNA synthetase -1.2428
RPUSD4 RNA pseudouridylate synthase domain containing 4 -1.23853
HSPA14 heat shock 70kDa protein 14 -1.23413
BIN1 bridging integrator 1 -1.23246
RAB8B RAB8B, member RAS oncogene family -1.2294
GRIK1 glutamate receptor, ionotropic, kainate 1 -1.22746
YIPF4 Yip1 domain family, member 4 -1.21898
CNIH2 cornichon family AMPA receptor auxiliary protein 2 -1.21535
GUCA1A guanylate cyclase activator 1A (retina) -1.21077
AKTIP AKT interacting protein -1.20178
VEGFB vascular endothelial growth factor B -1.19904
RFC2 replication factor C (activator 1) 2, 40kDa -1.19857
CDT1 chromatin licensing and DNA replication factor 1 -1.19728
FAM107B family with sequence similarity 107, member B -1.1958
UBAP1 ubiquitin associated protein 1 -1.19476
SFXN2 sideroflexin 2 -1.18485
IFI30 interferon, gamma-inducible protein 30 -1.17638
FZD9 frizzled class receptor 9 -1.17568
SHF Src homology 2 domain containing F -1.17487
MED14 mediator complex subunit 14 -1.17297
FAM173A family with sequence similarity 173, member A -1.17238
ITM2B integral membrane protein 2B -1.1679
CARHSP1 calcium regulated heat stable protein 1, 24kDa -1.16649
WWTR1 WW domain containing transcription regulator 1 -1.15982
SORBS1 sorbin and SH3 domain containing 1 -1.15392
FKBP2 FK506 binding protein 2, 13kDa -1.15157
PTGES2 prostaglandin E synthase 2 -1.14172
SIAH1 siah E3 ubiquitin protein ligase 1 -1.13999
MTX2 metaxin 2 -1.13928
WDR77 WD repeat domain 77 -1.13891
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -1.13732
IGFBP4 insulin-like growth factor binding protein 4 -1.13514
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -1.13395
MMP12 matrix metallopeptidase 12 -1.12901
PAWR PRKC, apoptosis, WT1, regulator -1.12486
TOP1 topoisomerase (DNA) I -1.12321
TIPRL TOR signaling pathway regulator -1.11608
ANXA5 annexin A5 -1.11327
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 -1.10872
PADI2 peptidyl arginine deiminase, type II -1.10725
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -1.10281
ANAPC2 anaphase promoting complex subunit 2 -1.10259
ALDOA aldolase A, fructose-bisphosphate -1.10013
SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 -1.09825
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) -1.08866
MINPP1 multiple inositol-polyphosphate phosphatase 1 -1.08454
WDR81 WD repeat domain 81 -1.08423
POU5F1 POU class 5 homeobox 1 -1.08417
SPARCL1 SPARC-like 1 (hevin) -1.07902
BUB3 BUB3 mitotic checkpoint protein -1.07149
PHB prohibitin -1.07138
PPL periplakin -1.06982
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase -1.0698
RBM38 RNA binding motif protein 38 -1.06953
RBPJ recombination signal binding protein for immunoglobulin kappa J region -1.06661
DKK3 dickkopf WNT signaling pathway inhibitor 3 -1.06544
LAPTM5 lysosomal protein transmembrane 5 -1.06368
BSG basigin (Ok blood group) -1.05801
ISLR immunoglobulin superfamily containing leucine-rich repeat -1.05449
PAQR7 progestin and adipoQ receptor family member VII -1.0542
SGPL1 sphingosine-1-phosphate lyase 1 -1.0525
TCF4 transcription factor 4 -1.05052
ERO1LB ERO1-like beta (S. cerevisiae) -1.04442
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 -1.04393
DYNLL2 dynein, light chain, LC8-type 2 -1.04167
TTC27 tetratricopeptide repeat domain 27 -1.04011
MTMR9 myotubularin related protein 9 -1.03852
SNAPIN SNAP-associated protein -1.03735
SEC62 SEC62 homolog (S. cerevisiae) -1.03315
CLTC clathrin, heavy chain (Hc) -1.02609
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -1.0236
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa -1.02247
TSC2 tuberous sclerosis 2 -1.02232
CANT1 calcium activated nucleotidase 1 -1.0205
CENPK centromere protein K -1.01491
RPTN repetin -1.01043
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -1.00865
CCDC64 coiled-coil domain containing 64 -1.00827
UBQLN4 ubiquilin 4 -0.998392
MAP2K4 mitogen-activated protein kinase kinase 4 -0.994193
SIRPA signal-regulatory protein alpha -0.989468
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c -0.989046
NUDCD3 NudC domain containing 3 -0.988013
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -0.986914
NTHL1 nth endonuclease III-like 1 (E. coli) -0.985898
CLIP1 CAP-GLY domain containing linker protein 1 -0.984319
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -0.980068
NXF1 nuclear RNA export factor 1 -0.977261
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein -0.975519
CNOT1 CCR4-NOT transcription complex, subunit 1 -0.97314
CETN3 centrin, EF-hand protein, 3 -0.970222
CDHR5 cadherin-related family member 5 -0.970089
PRSS1 protease, serine, 1 (trypsin 1) -0.969184
CD59 CD59 molecule, complement regulatory protein -0.967778
GIPC1 GIPC PDZ domain containing family, member 1 -0.967378
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A -0.965635
AOX1 aldehyde oxidase 1 -0.965174
SOWAHC sosondowah ankyrin repeat domain family member C -0.963599
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa -0.962392
PDZK1 PDZ domain containing 1 -0.957223
CECR6 cat eye syndrome chromosome region, candidate 6 -0.956501
FKBP9 FK506 binding protein 9, 63 kDa -0.956276
LDAH lipid droplet associated hydrolase -0.956244
HIST1H2BI histone cluster 1, H2bi -0.955955
C9ORF3 chromosome 9 open reading frame 3 -0.95594
GLG1 golgi glycoprotein 1 -0.952653
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -0.95168
NUP85 nucleoporin 85kDa -0.951448
HLA-DRA major histocompatibility complex, class II, DR alpha -0.951406
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -0.951119
IYD iodotyrosine deiodinase -0.951021
SEPHS1 selenophosphate synthetase 1 -0.947753
FBN1 fibrillin 1 -0.945832
RNASEH2A ribonuclease H2, subunit A -0.94308
CHD8 chromodomain helicase DNA binding protein 8 -0.940876
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) -0.940159
PSPH phosphoserine phosphatase -0.939503
TMEM59 transmembrane protein 59 -0.934471
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5 -0.927924
GATA2 GATA binding protein 2 -0.92704
RBM4B RNA binding motif protein 4B -0.925949
PRELID1 PRELI domain containing 1 -0.924789
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -0.92454
PRMT6 protein arginine methyltransferase 6 -0.924018
MRPL28 mitochondrial ribosomal protein L28 -0.921668
TMEM185A transmembrane protein 185A -0.921591
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 -0.91813
CALU calumenin -0.9174
PPIA peptidylprolyl isomerase A (cyclophilin A) -0.915309
IFIH1 interferon induced with helicase C domain 1 -0.91201
PRKACA protein kinase, cAMP-dependent, catalytic, alpha -0.905143
ACAA2 acetyl-CoA acyltransferase 2 -0.903386
IL1RN interleukin 1 receptor antagonist -0.902823
OR4C3 olfactory receptor, family 4, subfamily C, member 3 -0.901951
GHITM growth hormone inducible transmembrane protein -0.90167
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -0.900392
GATA5 GATA binding protein 5 -0.899906
CHKA choline kinase alpha -0.899742
RNF5 ring finger protein 5, E3 ubiquitin protein ligase -0.897231
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.893117
ATXN10 ataxin 10 -0.892363
FAM20C family with sequence similarity 20, member C -0.891667
CPN1 carboxypeptidase N, polypeptide 1 -0.890437
MIDN midnolin -0.888028
SSTR1 somatostatin receptor 1 -0.887221
SBNO1 strawberry notch homolog 1 (Drosophila) -0.885932
COL5A2 collagen, type V, alpha 2 -0.884691
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -0.88326
PARP1 poly (ADP-ribose) polymerase 1 -0.882278
CLPS colipase, pancreatic -0.880355
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa -0.877764
RFC1 replication factor C (activator 1) 1, 145kDa -0.877461
GOLGA3 golgin A3 -0.873705
PTCH1 patched 1 -0.870552
JUN jun proto-oncogene -0.869388
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -0.868054
LHX8 LIM homeobox 8 -0.866674
GSTM1 glutathione S-transferase mu 1 -0.865968