Cushing Syndrome Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description An adrenal gland hyperfunction that is caused by overactivity of the adrenal cortex caused by a tumor of the pituitary gland. (Human Disease Ontology, DOID_12252)
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Genes

16 genes associated with the Cushing Syndrome phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACE angiotensin I converting enzyme
ARMC5 armadillo repeat containing 5
DOT1L DOT1-like histone H3K79 methyltransferase
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
GNAS GNAS complex locus
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
PDE11A phosphodiesterase 11A
PDE8B phosphodiesterase 8B
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
VWF von Willebrand factor