Crohn's disease Gene Set

Dataset GWAS Catalog SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description An intestinal disease that involves inflammation located_in intestine. (Human Disease Ontology, DOID_8778)
External Link https://www.ebi.ac.uk/gwas/search?query=Crohn's disease
Similar Terms
Downloads & Tools

Genes

71 genes associated with the Crohn's disease phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
NOD2 nucleotide-binding oligomerization domain containing 2 2.39812
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 1.7104
IL23R interleukin 23 receptor 1.67118
CARD9 caspase recruitment domain family, member 9 1.37125
ZMIZ1 zinc finger, MIZ-type containing 1 1.29059
SBNO2 strawberry notch homolog 2 (Drosophila) 1.09468
LACC1 laccase (multicopper oxidoreductase) domain containing 1 1.08247
MUC19 mucin 19, oligomeric 1.06753
C5ORF56 chromosome 5 open reading frame 56 1.06007
SMAD3 SMAD family member 3 1.00661
GPR65 G protein-coupled receptor 65 0.964741
MST1 macrophage stimulating 1 0.920487
KSR1 kinase suppressor of ras 1 0.912347
SP140 SP140 nuclear body protein 0.910257
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 0.896275
UBE2L3 ubiquitin-conjugating enzyme E2L 3 0.877381
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 0.863028
FUT2 fucosyltransferase 2 (secretor status included) 0.863028
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.849268
PHTF1 putative homeodomain transcription factor 1 0.849268
ZGPAT zinc finger, CCCH-type with G patch domain 0.841354
PTPN2 protein tyrosine phosphatase, non-receptor type 2 0.817441
C21ORF33 chromosome 21 open reading frame 33 0.802698
THADA thyroid adenoma associated 0.802698
LOC285626 uncharacterized LOC285626 0.781677
SCAMP3 secretory carrier membrane protein 3 0.750033
FGFR1OP FGFR1 oncogene partner 0.713153
TYK2 tyrosine kinase 2 0.713153
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.696558
IL18RAP interleukin 18 receptor accessory protein 0.696558
ANKRD55 ankyrin repeat domain 55 0.679413
RNASET2 ribonuclease T2 0.661873
MROH3P maestro heat-like repeat family member 3, pseudogene 0.656287
TMEM258 transmembrane protein 258 0.637972
CLN3 ceroid-lipofuscinosis, neuronal 3 0.637972
GCKR glucokinase (hexokinase 4) regulator 0.612268
ERAP2 endoplasmic reticulum aminopeptidase 2 0.592545
PPP5C protein phosphatase 5, catalytic subunit 0.572839
RSPO3 R-spondin 3 0.552116
LOC102723878 uncharacterized LOC102723878 0.539238
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.526478
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.526478
CCNY cyclin Y 0.522843
ITLN1 intelectin 1 (galactofuranose binding) 0.522843
IL2RA interleukin 2 receptor, alpha 0.483518
PLCL1 phospholipase C-like 1 0.472799
JAZF1 JAZF zinc finger 1 0.472799
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.463473
PUS10 pseudouridylate synthase 10 0.463473
CPEB4 cytoplasmic polyadenylation element binding protein 4 0.463473
SLC22A23 solute carrier family 22, member 23 0.449549
TMEM17 transmembrane protein 17 0.449549
PER3 period circadian clock 3 0.449549
ZNF365 zinc finger protein 365 0.449549
ELF1 E74-like factor 1 (ets domain transcription factor) 0.444144
DENND1B DENN/MADD domain containing 1B 0.439318
MLN motilin 0.434785
SLAIN2 SLAIN motif family, member 2 0.405958
LINC00492 long intergenic non-protein coding RNA 492 0.405958
SBSPON somatomedin B and thrombospondin, type 1 domain containing 0.405958
PTRF polymerase I and transcript release factor 0.389385
SKAP2 src kinase associated phosphoprotein 2 0.389385
BSN bassoon presynaptic cytomatrix protein 0.377988
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 0.314454
C1ORF106 chromosome 1 open reading frame 106 0.314454
FCHSD2 FCH and double SH3 domains 2 0.280662
CD244 CD244 molecule, natural killer cell receptor 2B4 0.255654
PSORS1C3 psoriasis susceptibility 1 candidate 3 (non-protein coding) 0.246511
NELL1 NEL-like 1 (chicken) 0.129504
JAK2 Janus kinase 2 0.085234
RUNX3 runt-related transcription factor 3 0.042592