Coronary heart disease Gene Set

Dataset GWAS Catalog SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles. (Human Disease Ontology, DOID_3393)
External Link https://www.ebi.ac.uk/gwas/search?query=Coronary heart disease
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Genes

73 genes associated with the Coronary heart disease phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
CDKN2B-AS1 CDKN2B antisense RNA 1 1.47814
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.3386
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 1.259
PHACTR1 phosphatase and actin regulator 1 1.18694
PPAP2B phosphatidic acid phosphatase type 2B 1.00206
ZC3HC1 zinc finger, C3HC-type containing 1 0.95183
ZPR1 ZPR1 zinc finger 0.950225
C6ORF10 chromosome 6 open reading frame 10 0.841354
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.786836
LIPA lipase A, lysosomal acid, cholesterol esterase 0.740948
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 0.729497
MRAS muscle RAS oncogene homolog 0.721487
TCF21 transcription factor 21 0.713153
KIAA1462 KIAA1462 0.656287
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 0.637972
LPA lipoprotein, Lp(a) 0.626595
ACAD10 acyl-CoA dehydrogenase family, member 10 0.612268
HHIPL1 HHIP-like 1 0.592545
PSRC1 proline/serine-rich coiled-coil 1 0.560615
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.539238
SMG6 SMG6 nonsense mediated mRNA decay factor 0.526478
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 0.522843
WDR12 WD repeat domain 12 0.522843
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.522843
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.444144
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 0.434785
MIA3 melanoma inhibitory activity family, member 3 0.434785
LOC157273 uncharacterized LOC157273 0.434785
UBE2Z ubiquitin-conjugating enzyme E2Z 0.405958
BCAP29 B-cell receptor-associated protein 29 0.389385
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 0.389385
SLC12A9 solute carrier family 12, member 9 0.389385
KLHL29 kelch-like family member 29 0.342586
SMAD3 SMAD family member 3 0.314454
UBE2Q2P1 ubiquitin-conjugating enzyme E2Q family member 2 pseudogene 1 0.295129
PPP1R12B protein phosphatase 1, regulatory subunit 12B 0.295129
HNF1A HNF1 homeobox A 0.266721
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.266721
RNF130 ring finger protein 130 0.255654
FLT1 fms-related tyrosine kinase 1 0.255654
NLRC5 NLR family, CARD domain containing 5 0.255654
IL6R interleukin 6 receptor 0.246511
FNDC1 fibronectin type III domain containing 1 0.238523
DNM2 dynamin 2 0.22914
CHRDL1 chordin-like 1 0.22914
PECAM1 platelet/endothelial cell adhesion molecule 1 0.220915
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.220915
ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 0.220915
CUX2 cut-like homeobox 2 0.220915
FMN2 formin 2 0.165905
LINC00333 long intergenic non-protein coding RNA 333 0.165905
BTD biotinidase 0.165905
PDGFD platelet derived growth factor D 0.129504
LOC101929633 uncharacterized LOC101929633 0.129504
LITAF lipopolysaccharide-induced TNF factor 0.129504
SEZ6L seizure related 6 homolog (mouse)-like 0.104568
TNIK TRAF2 and NCK interacting kinase 0.104568
LAMC2 laminin, gamma 2 0.104568
OPRM1 opioid receptor, mu 1 0.085234
DOCK6 dedicator of cytokinesis 6 0.085234
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 0.085234
ZFHX3 zinc finger homeobox 3 0.085234
ASIC2 acid sensing (proton gated) ion channel 2 0.070053
DTNB dystrobrevin, beta 0.070053
SH2B3 SH2B adaptor protein 3 0.070053
CDH13 cadherin 13 0.070053
CSMD1 CUB and Sushi multiple domains 1 0.070053
FN1 fibronectin 1 0.057619
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.057619
EDC4 enhancer of mRNA decapping 4 0.048624
IGSF5 immunoglobulin superfamily, member 5 0.042592
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.042592
PLEKHO2 pleckstrin homology domain containing, family O member 2 0.042592