Coronary Vasospasm Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D003329
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Genes

221 genes/proteins associated with the disease Coronary Vasospasm from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
ARHGAP9 Rho GTPase activating protein 9 2.88009
NOS3 nitric oxide synthase 3 (endothelial cell) 2.88009
PON1 paraoxonase 1 2.88009
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.26633
FOS FBJ murine osteosarcoma viral oncogene homolog 2.21447
BAX BCL2-associated X protein 2.1909
MAPK1 mitogen-activated protein kinase 1 2.18214
TNF tumor necrosis factor 2.17469
NOS2 nitric oxide synthase 2, inducible 2.15447
CALCA calcitonin-related polypeptide alpha 2.13687
MAPK3 mitogen-activated protein kinase 3 2.11541
VEGFA vascular endothelial growth factor A 2.10642
IL1B interleukin 1, beta 2.09405
BCL2 B-cell CLL/lymphoma 2 2.0711
IL6 interleukin 6 2.06343
NPPA natriuretic peptide A 2.05771
SOD2 superoxide dismutase 2, mitochondrial 2.00219
CAT catalase 1.98843
REN renin 1.97771
FAS Fas cell surface death receptor 1.96402
EDN1 endothelin 1 1.95224
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.92375
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.91435
PARP1 poly (ADP-ribose) polymerase 1 1.88638
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.87311
TGFB1 transforming growth factor, beta 1 1.87244
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.8716
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.86427
EGFR epidermal growth factor receptor 1.85992
FASLG Fas ligand (TNF superfamily, member 6) 1.85764
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.8487
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.83841
EGR1 early growth response 1 1.83574
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.83467
BCL2L1 BCL2-like 1 1.80943
DDIT3 DNA-damage-inducible transcript 3 1.8068
IL10 interleukin 10 1.80019
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.7977
BDNF brain-derived neurotrophic factor 1.78416
HMOX1 heme oxygenase 1 1.76694
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.76269
TAC1 tachykinin, precursor 1 1.754
MAPK8 mitogen-activated protein kinase 8 1.69888
INS insulin 1.69825
CXCL8 chemokine (C-X-C motif) ligand 8 1.69361
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.6819
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.67933
PRKCD protein kinase C, delta 1.67072
NPPB natriuretic peptide B 1.64618
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.63989
CDK2 cyclin-dependent kinase 2 1.63518
JUN jun proto-oncogene 1.63317
NGF nerve growth factor (beta polypeptide) 1.63049
CCL2 chemokine (C-C motif) ligand 2 1.6287
RB1 retinoblastoma 1 1.62825
MMP9 matrix metallopeptidase 9 1.61248
CREB1 cAMP responsive element binding protein 1 1.61178
POMC proopiomelanocortin 1.60617
GSK3B glycogen synthase kinase 3 beta 1.59264
SOD1 superoxide dismutase 1, soluble 1.58137
MPO myeloperoxidase 1.58137
GFAP glial fibrillary acidic protein 1.56923
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.56386
ICAM1 intercellular adhesion molecule 1 1.56337
PRKCE protein kinase C, epsilon 1.56166
CCL3 chemokine (C-C motif) ligand 3 1.55673
ADRB2 adrenoceptor beta 2, surface 1.55476
MMP2 matrix metallopeptidase 2 1.55329
IL4 interleukin 4 1.55329
ADRB1 adrenoceptor beta 1 1.55133
CCND1 cyclin D1 1.54986
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.54548
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.53844
MAP2K1 mitogen-activated protein kinase kinase 1 1.53332
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.52187
VIM vimentin 1.51004
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.49992
LEP leptin 1.49686
TH tyrosine hydroxylase 1.48119
GAST gastrin 1.46621
BID BH3 interacting domain death agonist 1.46436
COL1A1 collagen, type I, alpha 1 1.45458
VCAM1 vascular cell adhesion molecule 1 1.45273
MAPK14 mitogen-activated protein kinase 14 1.43919
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.43864
CFLAR CASP8 and FADD-like apoptosis regulator 1.42669
JUNB jun B proto-oncogene 1.42047
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.41478
IL2 interleukin 2 1.41257
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.41035
TP53 tumor protein p53 1.40705
FGF2 fibroblast growth factor 2 (basic) 1.40457
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.40204
GSTP1 glutathione S-transferase pi 1 1.39924
SPP1 secreted phosphoprotein 1 1.3931
DUSP1 dual specificity phosphatase 1 1.38641
BIRC5 baculoviral IAP repeat containing 5 1.38555
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 1.34635
IFNG interferon, gamma 1.34256
CYCS cytochrome c, somatic 1.33995
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.33612
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.33553
PCNA proliferating cell nuclear antigen 1.33287
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.32905
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.32726
CRH corticotropin releasing hormone 1.30788
IL5 interleukin 5 1.30512
BAD BCL2-associated agonist of cell death 1.3036
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.29936
CLU clusterin 1.29471
IL1RN interleukin 1 receptor antagonist 1.2941
BAK1 BCL2-antagonist/killer 1 1.29011
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.28827
TIMP1 TIMP metallopeptidase inhibitor 1 1.28734
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.28241
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.28058
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.27782
F3 coagulation factor III (thromboplastin, tissue factor) 1.2772
GCG glucagon 1.27009
ADORA2A adenosine A2a receptor 1.27009
KLF4 Kruppel-like factor 4 (gut) 1.27009
ATF4 activating transcription factor 4 1.26638
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.26452
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.26421
CXCL10 chemokine (C-X-C motif) ligand 10 1.25776
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.25307
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.24843
MBP myelin basic protein 1.24591
EGF epidermal growth factor 1.24496
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.24401
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.2393
DRD2 dopamine receptor D2 1.2336
AVP arginine vasopressin 1.23011
NOS1 nitric oxide synthase 1 (neuronal) 1.2279
IL12B interleukin 12B 1.22632
FN1 fibronectin 1 1.22501
RPS6 ribosomal protein S6 1.21695
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.21468
PRKCA protein kinase C, alpha 1.20881
FKBP1B FK506 binding protein 1B, 12.6 kDa 1.2059
PENK proenkephalin 1.20196
FSHB follicle stimulating hormone, beta polypeptide 1.2013
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.20097
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.19999
APAF1 apoptotic peptidase activating factor 1 1.1977
MYL9 myosin, light chain 9, regulatory 1.19704
IGF1 insulin-like growth factor 1 (somatomedin C) 1.19445
GAL galanin/GMAP prepropeptide 1.19412
MMP1 matrix metallopeptidase 1 1.19379
TACR1 tachykinin receptor 1 1.19113
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.18751
H2AFX H2A histone family, member X 1.18652
G6PD glucose-6-phosphate dehydrogenase 1.18521
BDKRB2 bradykinin receptor B2 1.18521
CCND3 cyclin D3 1.17399
E2F3 E2F transcription factor 3 1.17202
NPY neuropeptide Y 1.16633
PHGDH phosphoglycerate dehydrogenase 1.16567
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.16302
MAOA monoamine oxidase A 1.16104
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.15189
CXCR4 chemokine (C-X-C motif) receptor 4 1.14989
CDK4 cyclin-dependent kinase 4 1.14919
XBP1 X-box binding protein 1 1.14816
PDE4B phosphodiesterase 4B, cAMP-specific 1.13415
CD44 CD44 molecule (Indian blood group) 1.13075
IGF1R insulin-like growth factor 1 receptor 1.12906
PRL prolactin 1.12357
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.12254
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.11536
PRLR prolactin receptor 1.10596
OXT oxytocin/neurophysin I prepropeptide 1.10596
IL1A interleukin 1, alpha 1.10353
TYMS thymidylate synthetase 1.10317
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.1014
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.09822
VIP vasoactive intestinal peptide 1.09751
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.09751
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.09471
HOMER1 homer scaffolding protein 1 1.09401
BIRC3 baculoviral IAP repeat containing 3 1.09047
CDK1 cyclin-dependent kinase 1 1.08442
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.08161
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.08126
NFE2L2 nuclear factor, erythroid 2-like 2 1.0784
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.07128
CTGF connective tissue growth factor 1.06808
PKM pyruvate kinase, muscle 1.06515
EPO erythropoietin 1.06116
GDF15 growth differentiation factor 15 1.0608
PTK2 protein tyrosine kinase 2 1.059
GJA1 gap junction protein, alpha 1, 43kDa 1.05386
TGFA transforming growth factor, alpha 1.05312
XDH xanthine dehydrogenase 1.05089
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.04721
BIRC2 baculoviral IAP repeat containing 2 1.04721
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.04538
MCL1 myeloid cell leukemia 1 1.04427
IRS1 insulin receptor substrate 1 1.04163
COCH cochlin 1.04088
STAR steroidogenic acute regulatory protein 1.03197
ADRB3 adrenoceptor beta 3 1.03197
COL3A1 collagen, type III, alpha 1 1.03197
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.03159
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.03046
EDNRB endothelin receptor type B 1.03009
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.02896
PLCG1 phospholipase C, gamma 1 1.02896
TGFB2 transforming growth factor, beta 2 1.02821
CCNB1 cyclin B1 1.02671
DRD1 dopamine receptor D1 1.02634
CD274 CD274 molecule 1.02596
GDNF glial cell derived neurotrophic factor 1.02336
HSPB1 heat shock 27kDa protein 1 1.02003
NCF1 neutrophil cytosolic factor 1 1.01928
CNR1 cannabinoid receptor 1 (brain) 1.01928
NUPR1 nuclear protein, transcriptional regulator, 1 1.01739
ERN1 endoplasmic reticulum to nucleus signaling 1 1.01249
CCND2 cyclin D2 1.01212
E2F1 E2F transcription factor 1 1.01025
IL12A interleukin 12A 1.01025