Copper Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
External Link http://ctdbase.org/detail.go?type=chem&acc=D003300
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Genes

370 genes/proteins interacting with the chemical Copper from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACO1 aconitase 1, soluble
ACO2 aconitase 2, mitochondrial
ACTG1 actin gamma 1
ACY1 aminoacylase 1
ADRB2 adrenoceptor beta 2, surface
AHR aryl hydrocarbon receptor
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALAD aminolevulinate dehydratase
ALB albumin
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANXA1 annexin A1
ANXA4 annexin A4
ANXA5 annexin A5
AOC1 amine oxidase, copper containing 1
APAF1 apoptotic peptidase activating factor 1
APLP2 amyloid beta (A4) precursor-like protein 2
APOA1 apolipoprotein A-I
APOB apolipoprotein B
APP amyloid beta (A4) precursor protein
AQP8 aquaporin 8
AR androgen receptor
ARG1 arginase 1
ARG2 arginase 2
ARNT aryl hydrocarbon receptor nuclear translocator
ATF1 activating transcription factor 1
ATF2 activating transcription factor 2
ATF3 activating transcription factor 3
ATOX1 antioxidant 1 copper chaperone
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATP7B ATPase, Cu++ transporting, beta polypeptide
B2M beta-2-microglobulin
BAD BCL2-associated agonist of cell death
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BID BH3 interacting domain death agonist
BMX BMX non-receptor tyrosine kinase
CA2 carbonic anhydrase II
CALR calreticulin
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAT catalase
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCNA2 cyclin A2
CCND1 cyclin D1
CCND2 cyclin D2
CCND3 cyclin D3
CCNDBP1 cyclin D-type binding-protein 1
CCNE1 cyclin E1
CCS copper chaperone for superoxide dismutase
CDC37 cell division cycle 37
CDK7 cyclin-dependent kinase 7
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CFL1 cofilin 1 (non-muscle)
CHAF1A chromatin assembly factor 1, subunit A (p150)
CHEK2 checkpoint kinase 2
CKM creatine kinase, muscle
CLIC1 chloride intracellular channel 1
CLU clusterin
COMMD1 copper metabolism (Murr1) domain containing 1
COX1
COX17 COX17 cytochrome c oxidase copper chaperone
COX2
COX4I1 cytochrome c oxidase subunit IV isoform 1
COX5B cytochrome c oxidase subunit Vb
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
CP ceruloplasmin (ferroxidase)
CREB1 cAMP responsive element binding protein 1
CRYAB crystallin, alpha B
CRYZ crystallin, zeta (quinone reductase)
CSE1L CSE1 chromosome segregation 1-like (yeast)
CWC22 CWC22 spliceosome-associated protein
CXCL8 chemokine (C-X-C motif) ligand 8
CYB5R3 cytochrome b5 reductase 3
CYCS cytochrome c, somatic
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
DDT D-dopachrome tautomerase
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DLD dihydrolipoamide dehydrogenase
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
EDN1 endothelin 1
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EGFR epidermal growth factor receptor
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EIF4A1 eukaryotic translation initiation factor 4A1
EIF6 eukaryotic translation initiation factor 6
ELN elastin
ENO1 enolase 1, (alpha)
ENO3 enolase 3 (beta, muscle)
EP300 E1A binding protein p300
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
F3 coagulation factor III (thromboplastin, tissue factor)
F8 coagulation factor VIII, procoagulant component
FAS Fas cell surface death receptor
FASN fatty acid synthase
FBLN1 fibulin 1
FBLN5 fibulin 5
FBN1 fibrillin 1
FGF1 fibroblast growth factor 1 (acidic)
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO1 forkhead box O1
FOXO4 forkhead box O4
FUS FUS RNA binding protein
FYN FYN proto-oncogene, Src family tyrosine kinase
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GLRA1 glycine receptor, alpha 1
GLUL glutamate-ammonia ligase
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GPC1 glypican 1
GPI glucose-6-phosphate isomerase
GPX1 glutathione peroxidase 1
GPX4 glutathione peroxidase 4
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GSK3B glycogen synthase kinase 3 beta
GSR glutathione reductase
GSS glutathione synthetase
GSTA1 glutathione S-transferase alpha 1
GSTA2 glutathione S-transferase alpha 2
HDGF hepatoma-derived growth factor
HEPH hephaestin
HEPHL1 hephaestin-like 1
HFE hemochromatosis
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST1H1B histone cluster 1, H1b
HMBS hydroxymethylbilane synthase
HMOX1 heme oxygenase 1
HNF4A hepatocyte nuclear factor 4, alpha
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HNRNPF heterogeneous nuclear ribonucleoprotein F
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9)
HNRNPK heterogeneous nuclear ribonucleoprotein K
HNRNPL heterogeneous nuclear ribonucleoprotein L
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HPX hemopexin
HRAS Harvey rat sarcoma viral oncogene homolog
HRG histidine-rich glycoprotein
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPB6 heat shock protein, alpha-crystallin-related, B6
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HTN3 histatin 3
HTT huntingtin
ICAM1 intercellular adhesion molecule 1
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IGFBP6 insulin-like growth factor binding protein 6
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL10 interleukin 10
IL12B interleukin 12B
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL5 interleukin 5
IL6 interleukin 6
INS insulin
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
JUN jun proto-oncogene
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KDR kinase insert domain receptor
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KRT8 keratin 8, type II
LAMB3 laminin, beta 3
LAMP1 lysosomal-associated membrane protein 1
LATS2 large tumor suppressor kinase 2
LCAT lecithin-cholesterol acyltransferase
LCN2 lipocalin 2
LDHA lactate dehydrogenase A
LOX lysyl oxidase
LPA lipoprotein, Lp(a)
LRP1 low density lipoprotein receptor-related protein 1
LYAR Ly1 antibody reactive
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MAPT microtubule-associated protein tau
MBP myelin basic protein
MKI67 marker of proliferation Ki-67
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MPO myeloperoxidase
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MT1A metallothionein 1A
MT2A metallothionein 2A
MT3 metallothionein 3
MTF1 metal-regulatory transcription factor 1
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NEIL2 nei endonuclease VIII-like 2 (E. coli)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGB neuroglobin
NME1 NME/NM23 nucleoside diphosphate kinase 1
NMT1 N-myristoyltransferase 1
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NQO1 NAD(P)H dehydrogenase, quinone 1
NRF1 nuclear respiratory factor 1
NUMA1 nuclear mitotic apparatus protein 1
OPRD1 opioid receptor, delta 1
OPRK1 opioid receptor, kappa 1
OPRM1 opioid receptor, mu 1
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
P4HB prolyl 4-hydroxylase, beta polypeptide
PABPN1 poly(A) binding protein, nuclear 1
PAM peptidylglycine alpha-amidating monooxygenase
PARP1 poly (ADP-ribose) polymerase 1
PCBP1 poly(rC) binding protein 1
PCBP2 poly(rC) binding protein 2
PDE5A phosphodiesterase 5A, cGMP-specific
PDIA3 protein disulfide isomerase family A, member 3
PEBP1 phosphatidylethanolamine binding protein 1
PFN1 profilin 1
PGAM1 phosphoglycerate mutase 1 (brain)
PGK1 phosphoglycerate kinase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PKM pyruvate kinase, muscle
PLAT plasminogen activator, tissue
PON1 paraoxonase 1
POR P450 (cytochrome) oxidoreductase
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRDX1 peroxiredoxin 1
PRDX2 peroxiredoxin 2
PRDX6 peroxiredoxin 6
PRKCA protein kinase C, alpha
PRL prolactin
PRLR prolactin receptor
PRND prion protein 2 (dublet)
PRNP prion protein
PRPF3 pre-mRNA processing factor 3
PSEN1 presenilin 1
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PTBP1 polypyrimidine tract binding protein 1
PTEN phosphatase and tensin homolog
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTK2 protein tyrosine kinase 2
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RAB4A RAB4A, member RAS oncogene family
RAD50 RAD50 homolog (S. cerevisiae)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RANBP1 RAN binding protein 1
RBM28 RNA binding motif protein 28
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RPS2 ribosomal protein S2
RPSA ribosomal protein SA
S100A13 S100 calcium binding protein A13
S100A8 S100 calcium binding protein A8
SATB1 SATB homeobox 1
SCO1 SCO1 cytochrome c oxidase assembly protein
SCO2 SCO2 cytochrome c oxidase assembly protein
SELE selectin E
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SF3A2 splicing factor 3a, subunit 2, 66kDa
SFPQ splicing factor proline/glutamine-rich
SH2B1 SH2B adaptor protein 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNRPA small nuclear ribonucleoprotein polypeptide A
SNRPA1 small nuclear ribonucleoprotein polypeptide A'
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SNRPC small nuclear ribonucleoprotein polypeptide C
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SNRPE small nuclear ribonucleoprotein polypeptide E
SNRPF small nuclear ribonucleoprotein polypeptide F
SNRPG small nuclear ribonucleoprotein polypeptide G
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOD3 superoxide dismutase 3, extracellular
SP1 Sp1 transcription factor
SP3 Sp3 transcription factor
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SREBF1 sterol regulatory element binding transcription factor 1
SRPK1 SRSF protein kinase 1
SRSF1 serine/arginine-rich splicing factor 1
SRSF2 serine/arginine-rich splicing factor 2
SRSF3 serine/arginine-rich splicing factor 3
SRSF5 serine/arginine-rich splicing factor 5
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STEAP2 STEAP family member 2, metalloreductase
STEAP3 STEAP family member 3, metalloreductase
STEAP4 STEAP family member 4
STIP1 stress-induced phosphoprotein 1
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
SYP synaptophysin
SYT1 synaptotagmin I
TARDBP TAR DNA binding protein
TF transferrin
TFAM transcription factor A, mitochondrial
TFDP1 transcription factor Dp-1
TFR2 transferrin receptor 2
TFRC transferrin receptor
THRSP thyroid hormone responsive
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TKT transketolase
TNF tumor necrosis factor
TNIK TRAF2 and NCK interacting kinase
TOP1 topoisomerase (DNA) I
TP53 tumor protein p53
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRH thyrotropin-releasing hormone
TRPM5 transient receptor potential cation channel, subfamily M, member 5
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSNAX translin-associated factor X
TTR transthyretin
TUBB tubulin, beta class I
TYR tyrosinase
U2AF1 U2 small nuclear RNA auxiliary factor 1
UBE2I ubiquitin-conjugating enzyme E2I
UGDH UDP-glucose 6-dehydrogenase
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VIM vimentin
WASF1 WAS protein family, member 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta