Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-1236382
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Genes

19 proteins participating in the Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants pathway from the Reactome Pathways dataset.

Symbol Name
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CDC37 cell division cycle 37
EGF epidermal growth factor
EGFR epidermal growth factor receptor
GAB1 GRB2-associated binding protein 1
GRB2 growth factor receptor-bound protein 2
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLCG1 phospholipase C, gamma 1
RPS27A ribosomal protein S27a
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SOS1 son of sevenless homolog 1 (Drosophila)
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C