Classical antibody-mediated complement activation Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-173623
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Genes

41 proteins participating in the Classical antibody-mediated complement activation pathway from the Reactome Pathways dataset.

Symbol Name
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QC complement component 1, q subcomponent, C chain
C1R complement component 1, r subcomponent
C1S complement component 1, s subcomponent
CRP C-reactive protein, pentraxin-related
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGHG2 immunoglobulin heavy constant gamma 2 (G2m marker)
IGHG3 immunoglobulin heavy constant gamma 3 (G3m marker)
IGHG4 immunoglobulin heavy constant gamma 4 (G4m marker)
IGHV7-81 immunoglobulin heavy variable 7-81 (non-functional)
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGLC1 immunoglobulin lambda constant 1 (Mcg marker)
IGLC2 immunoglobulin lambda constant 2 (Kern-Oz- marker)
IGLC3 immunoglobulin lambda constant 3 (Kern-Oz+ marker)
IGLC6 immunoglobulin lambda constant 6 (Kern+Oz- marker, gene/pseudogene)
IGLC7 immunoglobulin lambda constant 7
IGLV1-36 immunoglobulin lambda variable 1-36
IGLV1-40 immunoglobulin lambda variable 1-40
IGLV1-44 immunoglobulin lambda variable 1-44
IGLV10-54 immunoglobulin lambda variable 10-54
IGLV11-55 immunoglobulin lambda variable 11-55 (non-functional)
IGLV2-11 immunoglobulin lambda variable 2-11
IGLV2-18 immunoglobulin lambda variable 2-18
IGLV2-23 immunoglobulin lambda variable 2-23
IGLV2-33 immunoglobulin lambda variable 2-33 (non-functional)
IGLV3-12 immunoglobulin lambda variable 3-12
IGLV3-16 immunoglobulin lambda variable 3-16
IGLV3-22 immunoglobulin lambda variable 3-22 (gene/pseudogene)
IGLV3-25 immunoglobulin lambda variable 3-25
IGLV3-27 immunoglobulin lambda variable 3-27
IGLV4-3 immunoglobulin lambda variable 4-3
IGLV4-60 immunoglobulin lambda variable 4-60
IGLV4-69 immunoglobulin lambda variable 4-69
IGLV5-37 immunoglobulin lambda variable 5-37
IGLV5-45 immunoglobulin lambda variable 5-45
IGLV7-43 immunoglobulin lambda variable 7-43
IGLV7-46 immunoglobulin lambda variable 7-46 (gene/pseudogene)
IGLV8-61 immunoglobulin lambda variable 8-61