Class I MHC mediated antigen processing & presentation Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-983169
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Genes

255 proteins participating in the Class I MHC mediated antigen processing & presentation pathway from the Reactome Pathways dataset.

Symbol Name
ANAPC1 anaphase promoting complex subunit 1
ANAPC10 anaphase promoting complex subunit 10
ANAPC11 anaphase promoting complex subunit 11
ANAPC13 anaphase promoting complex subunit 13
ANAPC2 anaphase promoting complex subunit 2
ANAPC4 anaphase promoting complex subunit 4
ANAPC5 anaphase promoting complex subunit 5
ANAPC7 anaphase promoting complex subunit 7
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ASB1 ankyrin repeat and SOCS box containing 1
ASB10 ankyrin repeat and SOCS box containing 10
ASB11 ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase
ASB12 ankyrin repeat and SOCS box containing 12
ASB13 ankyrin repeat and SOCS box containing 13
ASB14 ankyrin repeat and SOCS box containing 14
ASB15 ankyrin repeat and SOCS box containing 15
ASB16 ankyrin repeat and SOCS box containing 16
ASB17 ankyrin repeat and SOCS box containing 17
ASB18 ankyrin repeat and SOCS box containing 18
ASB2 ankyrin repeat and SOCS box containing 2
ASB3 ankyrin repeat and SOCS box containing 3
ASB4 ankyrin repeat and SOCS box containing 4
ASB5 ankyrin repeat and SOCS box containing 5
ASB6 ankyrin repeat and SOCS box containing 6
ASB7 ankyrin repeat and SOCS box containing 7
ASB8 ankyrin repeat and SOCS box containing 8
ASB9 ankyrin repeat and SOCS box containing 9
ATG7 autophagy related 7
B2M beta-2-microglobulin
BLMH bleomycin hydrolase
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CALR calreticulin
CANX calnexin
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CD207 CD207 molecule, langerin
CD36 CD36 molecule (thrombospondin receptor)
CDC16 cell division cycle 16
CDC20 cell division cycle 20
CDC23 cell division cycle 23
CDC26 cell division cycle 26
CDC27 cell division cycle 27
CDC34 cell division cycle 34
CTSL cathepsin L
CTSS cathepsin S
CTSV cathepsin V
CUL1 cullin 1
CUL2 cullin 2
CUL3 cullin 3
CUL5 cullin 5
CUL7 cullin 7
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
DET1 de-etiolated homolog 1 (Arabidopsis)
DTX3L deltex 3 like, E3 ubiquitin ligase
DZIP3 DAZ interacting zinc finger protein 3
ERAP1 endoplasmic reticulum aminopeptidase 1
ERAP2 endoplasmic reticulum aminopeptidase 2
FBXO17 F-box protein 17
FBXO2 F-box protein 2
FBXO27 F-box protein 27
FBXO3 F-box protein 3
FBXO4 F-box protein 4
FBXO44 F-box protein 44
FBXO6 F-box protein 6
FBXW11 F-box and WD repeat domain containing 11
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FBXW8 F-box and WD repeat domain containing 8
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAN gigaxonin
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ITCH itchy E3 ubiquitin protein ligase
ITGAV integrin, alpha V
ITGB5 integrin, beta 5
KEAP1 kelch-like ECH-associated protein 1
KLHL13 kelch-like family member 13
KLHL20 kelch-like family member 20
KLHL21 kelch-like family member 21
KLHL9 kelch-like family member 9
LNPEP leucyl/cystinyl aminopeptidase
LRR1 leucine rich repeat protein 1
LRRC41 leucine rich repeat containing 41
LRSAM1 leucine rich repeat and sterile alpha motif containing 1
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MKRN1 makorin ring finger protein 1
MRC1 mannose receptor, C type 1
MRC2 mannose receptor, C type 2
NCF1 neutrophil cytosolic factor 1
NCF2 neutrophil cytosolic factor 2
NCF4 neutrophil cytosolic factor 4, 40kDa
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NPEPPS aminopeptidase puromycin sensitive
PARK2 parkin RBR E3 ubiquitin protein ligase
PDIA3 protein disulfide isomerase family A, member 3
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB11 proteasome (prosome, macropain) subunit, beta type, 11
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSME4 proteasome (prosome, macropain) activator subunit 4
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RBX1 ring-box 1, E3 ubiquitin protein ligase
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RNF111 ring finger protein 111
RNF123 ring finger protein 123
RNF138 ring finger protein 138, E3 ubiquitin protein ligase
RNF144B ring finger protein 144B
RNF182 ring finger protein 182
RNF19B ring finger protein 19B
RNF220 ring finger protein 220
RNF25 ring finger protein 25
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
RNF4 ring finger protein 4
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RNF6 ring finger protein (C3H2C3 type) 6
RPS27A ribosomal protein S27a
SAR1B secretion associated, Ras related GTPase 1B
SEC13 SEC13 homolog (S. cerevisiae)
SEC23A Sec23 homolog A (S. cerevisiae)
SEC24A SEC24 family member A
SEC24B SEC24 family member B
SEC24C SEC24 family member C
SEC24D SEC24 family member D
SEC31A SEC31 homolog A (S. cerevisiae)
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEC61B Sec61 beta subunit
SEC61G Sec61 gamma subunit
SKP1 S-phase kinase-associated protein 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SPSB2 splA/ryanodine receptor domain and SOCS box containing 2
SPSB4 splA/ryanodine receptor domain and SOCS box containing 4
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
TPP2 tripeptidyl peptidase II
TRIM11 tripartite motif containing 11
TRIM21 tripartite motif containing 21
TRIM32 tripartite motif containing 32
TRIM36 tripartite motif containing 36
TRIM37 tripartite motif containing 37
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase
TRIM9 tripartite motif containing 9
TRIP12 thyroid hormone receptor interactor 12
UBA1 ubiquitin-like modifier activating enzyme 1
UBA3 ubiquitin-like modifier activating enzyme 3
UBA5 ubiquitin-like modifier activating enzyme 5
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBA6 ubiquitin-like modifier activating enzyme 6
UBA7 ubiquitin-like modifier activating enzyme 7
UBB ubiquitin B
UBC ubiquitin C
UBE2A ubiquitin-conjugating enzyme E2A
UBE2B ubiquitin-conjugating enzyme E2B
UBE2C ubiquitin-conjugating enzyme E2C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2E2 ubiquitin-conjugating enzyme E2E 2
UBE2E3 ubiquitin-conjugating enzyme E2E 3
UBE2F ubiquitin-conjugating enzyme E2F (putative)
UBE2G1 ubiquitin-conjugating enzyme E2G 1
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UBE2H ubiquitin-conjugating enzyme E2H
UBE2J1 ubiquitin-conjugating enzyme E2, J1
UBE2J2 ubiquitin-conjugating enzyme E2, J2
UBE2K ubiquitin-conjugating enzyme E2K
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBE2M ubiquitin-conjugating enzyme E2M
UBE2N ubiquitin-conjugating enzyme E2N
UBE2O ubiquitin-conjugating enzyme E2O
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2
UBE2R2 ubiquitin-conjugating enzyme E2R 2
UBE2S ubiquitin-conjugating enzyme E2S
UBE2U ubiquitin-conjugating enzyme E2U (putative)
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UBE2Z ubiquitin-conjugating enzyme E2Z
UBE3A ubiquitin protein ligase E3A
UBE3B ubiquitin protein ligase E3B
UBE3C ubiquitin protein ligase E3C
UBE4A ubiquitination factor E4A
UBOX5 U-box domain containing 5
UBR1 ubiquitin protein ligase E3 component n-recognin 1
UBR2 ubiquitin protein ligase E3 component n-recognin 2
UBR4 ubiquitin protein ligase E3 component n-recognin 4
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VPRBP Vpr (HIV-1) binding protein
WSB1 WD repeat and SOCS box containing 1
WWP1 WW domain containing E3 ubiquitin protein ligase 1
ZBTB16 zinc finger and BTB domain containing 16