Chronic Periodontitis Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

99 genes associated with the Chronic Periodontitis phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ADGRE1 adhesion G protein-coupled receptor E1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
C5 complement component 5
CAMTA1 calmodulin binding transcription activator 1
CD14 CD14 molecule
CD28 CD28 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKN2B-AS1 CDKN2B antisense RNA 1
CRP C-reactive protein, pentraxin-related
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
DEFB1 defensin, beta 1
DEFB104B defensin, beta 104B
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FBXO38 F-box protein 38
FCAR Fc fragment of IgA receptor
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FGB fibrinogen beta chain
FHOD3 formin homology 2 domain containing 3
FPR1 formyl peptide receptor 1
GVINP1 GTPase, very large interferon inducible pseudogene 1
HAS2 hyaluronan synthase 2
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HLA-B major histocompatibility complex, class I, B
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HP haptoglobin
HSP90AB2P heat shock protein 90kDa alpha (cytosolic), class B member 2, pseudogene
IFIH1 interferon induced with helicase C domain 1
IFNG interferon, gamma
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL13 interleukin 13
IL17A interleukin 17A
IL17F interleukin 17F
IL17RA interleukin 17 receptor A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL33 interleukin 33
IL4 interleukin 4
IL6 interleukin 6
KCNK1 potassium channel, two pore domain subfamily K, member 1
LAMA2 laminin, alpha 2
LOC100506172
LTF lactotransferrin
MBL2 mannose-binding lectin (protein C) 2, soluble
MICB MHC class I polypeptide-related sequence B
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP3 matrix metallopeptidase 3
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MUC7 mucin 7, secreted
NCR2 natural cytotoxicity triggering receptor 2
NIN ninein (GSK3B interacting protein)
NPY neuropeptide Y
NR1I2 nuclear receptor subfamily 1, group I, member 2
NUAK1 NUAK family, SNF1-like kinase, 1
OSBPL10 oxysterol binding protein-like 10
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RUNX2 runt-related transcription factor 2
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SELE selectin E
SOS2 son of sevenless homolog 2 (Drosophila)
STAT1 signal transducer and activator of transcription 1, 91kDa
TANK TRAF family member-associated NFKB activator
TGFB1 transforming growth factor, beta 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TRPS1 trichorhinophalangeal syndrome I
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
VAMP3 vesicle-associated membrane protein 3
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
WNT5A wingless-type MMTV integration site family, member 5A