Chondroitin sulfate biosynthesis Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
Description The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. (Gene Ontology, GO_0030206)
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-2022870
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Genes

20 proteins participating in the Chondroitin sulfate biosynthesis pathway from the Reactome Pathways dataset.

Symbol Name
BCAN brevican
BGN biglycan
CHPF chondroitin polymerizing factor
CHPF2 chondroitin polymerizing factor 2
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CHST13 carbohydrate (chondroitin 4) sulfotransferase 13
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
CHSY1 chondroitin sulfate synthase 1
CHSY3 chondroitin sulfate synthase 3
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CSPG4 chondroitin sulfate proteoglycan 4
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
DCN decorin
NCAN neurocan
VCAN versican