Cholic Acid Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A bile acid that is 5beta-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12. (Chemical Entities of Biological Interest Ontology, CHEBI_16359)
External Link http://ctdbase.org/detail.go?type=chem&acc=D019826
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Genes

39 genes/proteins interacting with the chemical Cholic Acid from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
AKR1C4 aldo-keto reductase family 1, member C4
CAT catalase
CHEK1 checkpoint kinase 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
FOSL1 FOS-like antigen 1
GPBAR1 G protein-coupled bile acid receptor 1
GSTA1 glutathione S-transferase alpha 1
GSTA3 glutathione S-transferase alpha 3
GSTA4 glutathione S-transferase alpha 4
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
HELLS helicase, lymphoid-specific
IL1B interleukin 1, beta
IL1RL1 interleukin 1 receptor-like 1
LRP2 low density lipoprotein receptor-related protein 2
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MCM3 minichromosome maintenance complex component 3
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR1H4 nuclear receptor subfamily 1, group H, member 4
ORM1 orosomucoid 1
ORM2 orosomucoid 2
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PON1 paraoxonase 1
RIF1 replication timing regulatory factor 1
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SQSTM1 sequestosome 1
STMN1 stathmin 1
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
TFRC transferrin receptor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A