Chenodeoxycholic Acid Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A dihydroxy-5beta-cholanic acid that is (5beta)-cholan-24-oic acid substituted by hydroxy groups at positions 3 and 7 respectively. (Chemical Entities of Biological Interest Ontology, CHEBI_16755)
External Link http://ctdbase.org/detail.go?type=chem&acc=D002635
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Genes

46 genes/proteins interacting with the chemical Chenodeoxycholic Acid from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
AKR1C2 aldo-keto reductase family 1, member C2
APOA1 apolipoprotein A-I
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCL5 chemokine (C-C motif) ligand 5
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CXCL2 chemokine (C-X-C motif) ligand 2
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
EGR1 early growth response 1
FGF19 fibroblast growth factor 19
FOS FBJ murine osteosarcoma viral oncogene homolog
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GPBAR1 G protein-coupled bile acid receptor 1
GSTA4 glutathione S-transferase alpha 4
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HHEX hematopoietically expressed homeobox
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
JUN jun proto-oncogene
LRP2 low density lipoprotein receptor-related protein 2
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
NCOA1 nuclear receptor coactivator 1
NCOR1 nuclear receptor corepressor 1
NFE2L2 nuclear factor, erythroid 2-like 2
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR1I2 nuclear receptor subfamily 1, group I, member 2
PARP1 poly (ADP-ribose) polymerase 1
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC51A solute carrier family 51, alpha subunit
SLC51B solute carrier family 51, beta subunit
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SQSTM1 sequestosome 1
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
TXN thioredoxin
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3
VCAM1 vascular cell adhesion molecule 1