Cerebral Palsy Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A brain disease that is caused by damage to the motor control centers of the developing brain during pregnancy, during childbirth or after birth, which affects muscle movement and balance. (Human Disease Ontology, DOID_1969)
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Genes

46 genes associated with the Cerebral Palsy phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ADD1 adducin 1 (alpha)
ADRB2 adrenoceptor beta 2, surface
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANXA5 annexin A5
AP4B1 adaptor-related protein complex 4, beta 1 subunit
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
AP4M1 adaptor-related protein complex 4, mu 1 subunit
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
APOE apolipoprotein E
CBS cystathionine-beta-synthase
CXCL8 chemokine (C-X-C motif) ligand 8
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FGB fibrinogen beta chain
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
IL10 interleukin 10
IL18 interleukin 18
IL1B interleukin 1, beta
IL4 interleukin 4
IL6 interleukin 6
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
LTA lymphotoxin alpha
MBL2 mannose-binding lectin (protein C) 2, soluble
MMP3 matrix metallopeptidase 3
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPA natriuretic peptide A
PDE4D phosphodiesterase 4D, cAMP-specific
PLAT plasminogen activator, tissue
PROCR protein C receptor, endothelial
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SELE selectin E
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THBD thrombomodulin
TLR4 toll-like receptor 4
TNF tumor necrosis factor
VIP vasoactive intestinal peptide