Cataract Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A lens disease characterized by clouding of the lens inside the eye which leads to a decrease in vision. (Human Disease Ontology, DOID_83)
Similar Terms
Downloads & Tools

Genes

68 genes associated with the Cataract phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
BLM Bloom syndrome, RecQ helicase-like
C1ORF110 chromosome 1 open reading frame 110
CAT catalase
CCDC102A coiled-coil domain containing 102A
CRYAA crystallin, alpha A
CRYBB3 crystallin, beta B3
CRYGA crystallin, gamma A
CRYGB crystallin, gamma B
CTNND2 catenin (cadherin-associated protein), delta 2
DMPK dystrophia myotonica-protein kinase
EPHA2 EPH receptor A2
ERCC2 excision repair cross-complementation group 2
ERCC6 excision repair cross-complementation group 6
EZR ezrin
FAM19A1 family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
FTL ferritin, light polypeptide
FTO fat mass and obesity associated
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GALK1 galactokinase 1
GALNT16 polypeptide N-acetylgalactosaminyltransferase 16
GALT galactose-1-phosphate uridylyltransferase
GBA3 glucosidase, beta, acid 3 (gene/pseudogene)
GJA3 gap junction protein, alpha 3, 46kDa
GJA8 gap junction protein, alpha 8, 50kDa
GPX1 glutathione peroxidase 1
GSTM1 glutathione S-transferase mu 1
GSTO1 glutathione S-transferase omega 1
GSTO2 glutathione S-transferase omega 2
GSTT1 glutathione S-transferase theta 1
HSF4 heat shock transcription factor 4
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HSPA1L heat shock 70kDa protein 1-like
IFNGR1 interferon gamma receptor 1
IL13 interleukin 13
KEAP1 kelch-like ECH-associated protein 1
KIAA1671 KIAA1671
KLC1 kinesin light chain 1
LCT lactase
LIM2 lens intrinsic membrane protein 2, 19kDa
LMNA lamin A/C
LOXL1 lysyl oxidase-like 1
MIP major intrinsic protein of lens fiber
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFE2L2 nuclear factor, erythroid 2-like 2
OGG1 8-oxoguanine DNA glycosylase
PPARD peroxisome proliferator-activated receptor delta
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SLC16A12 solute carrier family 16, member 12
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOD3 superoxide dismutase 3, extracellular
TAC1 tachykinin, precursor 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
WRN Werner syndrome, RecQ helicase-like
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZNF616 zinc finger protein 616