Caspase Cascade in Apoptosis Gene Set

Dataset PID Pathways
Category structural or functional annotations
Type pathway
External Link http://public.ndexbio.org/#/network/b9d3ef2e-618f-11e5-8ac5-06603eb7f303
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Genes

55 proteins participating in the Caspase Cascade in Apoptosis pathway from the PID Pathways dataset.

Symbol Name
ACTA1 actin, alpha 1, skeletal muscle
AKT1 v-akt murine thymoma viral oncogene homolog 1
APAF1 apoptotic peptidase activating factor 1
APP amyloid beta (A4) precursor protein
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BID BH3 interacting domain death agonist
BIRC3 baculoviral IAP repeat containing 3
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CFL2 cofilin 2 (muscle)
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CYCS cytochrome c, somatic
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DIABLO diablo, IAP-binding mitochondrial protein
FADD Fas (TNFRSF6)-associated via death domain
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
GAS2 growth arrest-specific 2
GSN gelsolin
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
KRT18 keratin 18, type I
LIMK1 LIM domain kinase 1
LMNA lamin A/C
LMNB1 lamin B1
LMNB2 lamin B2
MADD MAP-kinase activating death domain
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
NUMA1 nuclear mitotic apparatus protein 1
PARP1 poly (ADP-ribose) polymerase 1
PIDD1 p53-induced death domain protein 1
PRF1 perforin 1 (pore forming protein)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
SATB1 SATB homeobox 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SREBF1 sterol regulatory element binding transcription factor 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOP1 topoisomerase (DNA) I
TRADD TNFRSF1A-associated via death domain
TRAF2 TNF receptor-associated factor 2
VIM vimentin
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase