Cardiac Hypertrophy_Myocardial tissue_GSE5500 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE5500
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Genes

600 genes differentially expressed during Cardiac Hypertrophy_Myocardial tissue_GSE5500 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
LXN latexin 4.72779
MEOX2 mesenchyme homeobox 2 3.76838
MAN2A1 mannosidase, alpha, class 2A, member 1 3.63024
FRZB frizzled-related protein 3.5718
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 3.5453
FAM102B family with sequence similarity 102, member B 3.43253
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 3.40281
LYN LYN proto-oncogene, Src family tyrosine kinase 3.26487
GAS2 growth arrest-specific 2 3.24287
ELOVL1 ELOVL fatty acid elongase 1 3.22622
CNN3 calponin 3, acidic 3.18965
MTMR12 myotubularin related protein 12 3.16508
FSTL1 follistatin-like 1 3.13747
WIPF1 WAS/WASL interacting protein family, member 1 3.12703
CMTM3 CKLF-like MARVEL transmembrane domain containing 3 3.08143
FAM198B family with sequence similarity 198, member B 3.05789
MEST mesoderm specific transcript 3.04715
ASPN asporin 3.03645
ESYT2 extended synaptotagmin-like protein 2 3.02257
MYH7 myosin, heavy chain 7, cardiac muscle, beta 2.96144
PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) 2.94657
CSRP2 cysteine and glycine-rich protein 2 2.87987
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 2.86944
ARMCX2 armadillo repeat containing, X-linked 2 2.81131
TSPAN6 tetraspanin 6 2.75792
POSTN periostin, osteoblast specific factor 2.7434
NID2 nidogen 2 (osteonidogen) 2.7282
LOXL1 lysyl oxidase-like 1 2.7214
C1QB complement component 1, q subcomponent, B chain 2.70739
NCKAP1L NCK-associated protein 1-like 2.70577
IL2RG interleukin 2 receptor, gamma 2.7018
CDK1 cyclin-dependent kinase 1 2.68952
FILIP1L filamin A interacting protein 1-like 2.67881
CAPG capping protein (actin filament), gelsolin-like 2.67371
ACSL5 acyl-CoA synthetase long-chain family member 5 2.67007
ICAM2 intercellular adhesion molecule 2 2.65577
PPIC peptidylprolyl isomerase C (cyclophilin C) 2.64536
DYNLL1 dynein, light chain, LC8-type 1 2.6448
CERCAM cerebral endothelial cell adhesion molecule 2.58976
VIM vimentin 2.57139
KCTD12 potassium channel tetramerization domain containing 12 2.55344
PRC1 protein regulator of cytokinesis 1 2.54709
TACC3 transforming, acidic coiled-coil containing protein 3 2.54705
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 2.53737
CENPT centromere protein T 2.53269
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 2.51876
TSPAN2 tetraspanin 2 2.51237
ITGA6 integrin, alpha 6 2.48528
CASP8 caspase 8, apoptosis-related cysteine peptidase 2.47356
ADSS adenylosuccinate synthase 2.47348
MFAP5 microfibrillar associated protein 5 2.45767
NUCB2 nucleobindin 2 2.4543
SNX7 sorting nexin 7 2.44814
SMAD1 SMAD family member 1 2.4364
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 2.43347
DPY19L1 dpy-19-like 1 (C. elegans) 2.43294
GPRC5B G protein-coupled receptor, class C, group 5, member B 2.43197
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 2.42902
TES testin LIM domain protein 2.42182
FMNL3 formin-like 3 2.41795
FAM129B family with sequence similarity 129, member B 2.41316
RAD51AP1 RAD51 associated protein 1 2.40955
NUAK1 NUAK family, SNF1-like kinase, 1 2.40166
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) 2.39959
H2AFZ H2A histone family, member Z 2.39756
SAMD9L sterile alpha motif domain containing 9-like 2.38875
COL6A3 collagen, type VI, alpha 3 2.38231
S100A10 S100 calcium binding protein A10 2.37939
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 2.36979
RGS19 regulator of G-protein signaling 19 2.36668
RELL1 RELT-like 1 2.36623
SH3BGRL SH3 domain binding glutamate-rich protein like 2.34262
SKA1 spindle and kinetochore associated complex subunit 1 2.33502
MCM6 minichromosome maintenance complex component 6 2.33431
TUBA1A tubulin, alpha 1a 2.31367
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 2.30937
MEOX1 mesenchyme homeobox 1 2.30475
TRIM47 tripartite motif containing 47 2.30352
S100A6 S100 calcium binding protein A6 2.29615
COL5A2 collagen, type V, alpha 2 2.29054
PTPN12 protein tyrosine phosphatase, non-receptor type 12 2.28874
CKS1B CDC28 protein kinase regulatory subunit 1B 2.28377
TSPAN14 tetraspanin 14 2.28318
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 2.27762
LBR lamin B receptor 2.26233
CTSZ cathepsin Z 2.24933
MCAM melanoma cell adhesion molecule 2.24923
NUPR1 nuclear protein, transcriptional regulator, 1 2.24788
MARCKSL1 MARCKS-like 1 2.23094
MRC1 mannose receptor, C type 1 2.21957
TGFBI transforming growth factor, beta-induced, 68kDa 2.2091
COL3A1 collagen, type III, alpha 1 2.20722
TGFB3 transforming growth factor, beta 3 2.19813
GDA guanine deaminase 2.19638
CEP170 centrosomal protein 170kDa 2.18098
LUM lumican 2.16196
MALL mal, T-cell differentiation protein-like 2.14913
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 2.13756
TSPO translocator protein (18kDa) 2.13429
C1ORF54 chromosome 1 open reading frame 54 2.12515
UHRF1 ubiquitin-like with PHD and ring finger domains 1 2.11613
PHTF1 putative homeodomain transcription factor 1 2.11545
PXDN peroxidasin 2.11173
PCDH17 protocadherin 17 2.10974
PRKCDBP protein kinase C, delta binding protein 2.1039
TUBB2B tubulin, beta 2B class IIb 2.08512
PLS3 plastin 3 2.07503
SEPT5 septin 5 2.06526
PLA1A phospholipase A1 member A 2.06411
CCR2 chemokine (C-C motif) receptor 2 2.06131
SHROOM4 shroom family member 4 2.05894
CHSY1 chondroitin sulfate synthase 1 2.0547
HAUS3 HAUS augmin-like complex, subunit 3 2.04067
C1QA complement component 1, q subcomponent, A chain 2.03478
ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein-like 2 2.03353
CD34 CD34 molecule 2.03318
H2AFX H2A histone family, member X 2.02739
KDELC2 KDEL (Lys-Asp-Glu-Leu) containing 2 2.01774
CTSK cathepsin K 2.01728
MYCT1 myc target 1 2.01486
COL6A2 collagen, type VI, alpha 2 2.00086
ALOX5AP arachidonate 5-lipoxygenase-activating protein 2.00013
FAM111A family with sequence similarity 111, member A 1.99926
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 1.99528
PRAF2 PRA1 domain family, member 2 1.99368
CKAP2 cytoskeleton associated protein 2 1.98931
TMEM237 transmembrane protein 237 1.9879
CYB561 cytochrome b561 1.98225
ANXA3 annexin A3 1.98073
CKS2 CDC28 protein kinase regulatory subunit 2 1.96565
ARHGAP11A Rho GTPase activating protein 11A 1.96444
TFPI2 tissue factor pathway inhibitor 2 1.96133
CD109 CD109 molecule 1.9567
F13A1 coagulation factor XIII, A1 polypeptide 1.95605
TRIB3 tribbles pseudokinase 3 1.94316
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 1.94201
TUBB tubulin, beta class I 1.94142
MYL9 myosin, light chain 9, regulatory 1.92484
TNFAIP8L1 tumor necrosis factor, alpha-induced protein 8-like 1 1.92311
HIGD1B HIG1 hypoxia inducible domain family, member 1B 1.92254
COL1A2 collagen, type I, alpha 2 1.92203
DCK deoxycytidine kinase 1.92177
COL18A1 collagen, type XVIII, alpha 1 1.92003
JUN jun proto-oncogene 1.91831
DAGLA diacylglycerol lipase, alpha 1.91818
SHCBP1 SHC SH2-domain binding protein 1 1.91728
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 1.91312
FAM64A family with sequence similarity 64, member A 1.90854
CSNK1G3 casein kinase 1, gamma 3 1.90372
ADCY7 adenylate cyclase 7 1.90234
FXYD5 FXYD domain containing ion transport regulator 5 1.89999
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 1.89816
COL5A1 collagen, type V, alpha 1 1.8962
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.89063
ARL4C ADP-ribosylation factor-like 4C 1.89026
EPS8 epidermal growth factor receptor pathway substrate 8 1.89016
UBE2L6 ubiquitin-conjugating enzyme E2L 6 1.88938
GIMAP8 GTPase, IMAP family member 8 1.88852
PDZD3 PDZ domain containing 3 1.88762
SRPX2 sushi-repeat containing protein, X-linked 2 1.88144
LPAR1 lysophosphatidic acid receptor 1 1.87855
IFT122 intraflagellar transport 122 1.87562
WBP5 WW domain binding protein 5 1.87557
SERTAD4 SERTA domain containing 4 1.87338
HEXB hexosaminidase B (beta polypeptide) 1.87285
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 1.86827
PGRMC1 progesterone receptor membrane component 1 1.86538
FAM91A1 family with sequence similarity 91, member A1 1.85989
WHSC1 Wolf-Hirschhorn syndrome candidate 1 1.85382
NDN necdin, melanoma antigen (MAGE) family member 1.85346
SLC38A4 solute carrier family 38, member 4 1.85295
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.84946
SOAT1 sterol O-acyltransferase 1 1.83915
IFIH1 interferon induced with helicase C domain 1 1.83568
CNOT6 CCR4-NOT transcription complex, subunit 6 1.83535
HMGB2 high mobility group box 2 1.83458
LSP1 lymphocyte-specific protein 1 1.83367
ORC6 origin recognition complex, subunit 6 1.83319
MYLK myosin light chain kinase 1.83276
TAGLN transgelin 1.82947
CCNYL1 cyclin Y-like 1 1.82027
AURKB aurora kinase B 1.81713
ANXA4 annexin A4 1.81614
RNF145 ring finger protein 145 1.8153
PRELID1 PRELI domain containing 1 1.81147
IFITM2 interferon induced transmembrane protein 2 1.81129
SGTB small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta 1.81089
CCND1 cyclin D1 1.8031
MCM3 minichromosome maintenance complex component 3 1.80175
GPR153 G protein-coupled receptor 153 1.80033
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 1.79938
E2F7 E2F transcription factor 7 1.79929
TIMP1 TIMP metallopeptidase inhibitor 1 1.79739
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 1.79431
IPO9 importin 9 1.79043
HN1 hematological and neurological expressed 1 1.77847
SYNPO synaptopodin 1.77585
SMC4 structural maintenance of chromosomes 4 1.77517
KDSR 3-ketodihydrosphingosine reductase 1.77296
ITGA1 integrin, alpha 1 1.76881
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 1.76244
FAM172A family with sequence similarity 172, member A 1.75981
DUSP26 dual specificity phosphatase 26 (putative) 1.75361
PLK4 polo-like kinase 4 1.75062
BGN biglycan 1.74927
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 1.74514
CRLF2 cytokine receptor-like factor 2 1.74325
IER5 immediate early response 5 1.74166
DPYSL3 dihydropyrimidinase-like 3 1.74068
AHNAK2 AHNAK nucleoprotein 2 1.73807
BRCA2 breast cancer 2, early onset 1.73698
IL3RA interleukin 3 receptor, alpha (low affinity) 1.73689
PNP purine nucleoside phosphorylase 1.73649
TGFB2 transforming growth factor, beta 2 1.73155
RBMS3 RNA binding motif, single stranded interacting protein 3 1.72968
PMP22 peripheral myelin protein 22 1.72695
CMIP c-Maf inducing protein 1.72385
FAM171A1 family with sequence similarity 171, member A1 1.72264
MCM5 minichromosome maintenance complex component 5 1.71803
FAM129A family with sequence similarity 129, member A 1.71474
DEK DEK proto-oncogene 1.71165
KCTD17 potassium channel tetramerization domain containing 17 1.70808
NRM nurim (nuclear envelope membrane protein) 1.70796
CDR2 cerebellar degeneration-related protein 2, 62kDa 1.70777
GXYLT1 glucoside xylosyltransferase 1 1.7054
TPM3 tropomyosin 3 1.70462
NANS N-acetylneuraminic acid synthase 1.70437
PECAM1 platelet/endothelial cell adhesion molecule 1 1.70311
TK1 thymidine kinase 1, soluble 1.70155
MATN2 matrilin 2 1.69917
SCPEP1 serine carboxypeptidase 1 1.6983
PRSS23 protease, serine, 23 1.69585
LITAF lipopolysaccharide-induced TNF factor 1.69528
TMEM165 transmembrane protein 165 1.69214
PGM2 phosphoglucomutase 2 1.69183
CD68 CD68 molecule 1.69061
ADAM18 ADAM metallopeptidase domain 18 1.68828
THY1 Thy-1 cell surface antigen 1.6846
BIRC5 baculoviral IAP repeat containing 5 1.68029
CPM carboxypeptidase M 1.67999
STX2 syntaxin 2 1.67836
SLC30A4 solute carrier family 30 (zinc transporter), member 4 1.6749
N4BP3 NEDD4 binding protein 3 1.67411
ADAM9 ADAM metallopeptidase domain 9 1.67147
PKD2 polycystic kidney disease 2 (autosomal dominant) 1.66361
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 1.66137
COL8A1 collagen, type VIII, alpha 1 1.66111
MYO1B myosin IB 1.66021
CST6 cystatin E/M 1.65914
COLEC12 collectin sub-family member 12 1.65903
PLK1 polo-like kinase 1 1.65295
PBK PDZ binding kinase 1.65275
YIPF5 Yip1 domain family, member 5 1.65212
COL6A1 collagen, type VI, alpha 1 1.64925
RPL3 ribosomal protein L3 1.64816
CARHSP1 calcium regulated heat stable protein 1, 24kDa 1.6437
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 1.64212
SERP1 stress-associated endoplasmic reticulum protein 1 1.64198
REEP3 receptor accessory protein 3 1.64155
NOSTRIN nitric oxide synthase trafficking 1.6381
CRIP1 cysteine-rich protein 1 (intestinal) 1.63792
DSEL dermatan sulfate epimerase-like 1.63704
PHLDA3 pleckstrin homology-like domain, family A, member 3 1.63666
RBP1 retinol binding protein 1, cellular 1.63137
PRND prion protein 2 (dublet) 1.62998
SYNPO2L synaptopodin 2-like 1.62822
PDE3B phosphodiesterase 3B, cGMP-inhibited 1.62752
ZMAT3 zinc finger, matrin-type 3 1.62326
BAX BCL2-associated X protein 1.62114
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 1.6209
ADAMTSL2 ADAMTS-like 2 1.62045
TAGLN2 transgelin 2 1.62023
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 1.6128
REEP4 receptor accessory protein 4 1.61173
MAPRE1 microtubule-associated protein, RP/EB family, member 1 1.61074
PCDH19 protocadherin 19 1.6102
TRAM1 translocation associated membrane protein 1 1.60909
CD9 CD9 molecule 1.60347
FBXO5 F-box protein 5 1.5988
SPARCL1 SPARC-like 1 (hevin) 1.59854
GUSB glucuronidase, beta 1.59849
NCAPD2 non-SMC condensin I complex, subunit D2 1.58587
ANO6 anoctamin 6 1.58541
CTGF connective tissue growth factor 1.58413
FYN FYN proto-oncogene, Src family tyrosine kinase 1.58349
PSAT1 phosphoserine aminotransferase 1 1.58265
MTMR2 myotubularin related protein 2 1.5798
EDA2R ectodysplasin A2 receptor 1.57512
PALD1 phosphatase domain containing, paladin 1 1.57366
KCNK6 potassium channel, two pore domain subfamily K, member 6 1.5729
DUSP3 dual specificity phosphatase 3 1.56963
GMDS GDP-mannose 4,6-dehydratase 1.56934
TUBA1C tubulin, alpha 1c 1.5682
GRN granulin 1.56559
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 1.56401
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 1.56327
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 1.56233
RTN4 reticulon 4 1.55629
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 1.55527
AIDA axin interactor, dorsalization associated 1.55341

decreased expression

Symbol Name Standardized Value
ZBTB11 zinc finger and BTB domain containing 11 -2.33778
LIG4 ligase IV, DNA, ATP-dependent -2.22615
C14ORF37 chromosome 14 open reading frame 37 -2.20918
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) -2.1533
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) -2.14851
RSF1 remodeling and spacing factor 1 -2.07872
AUTS2 autism susceptibility candidate 2 -2.02149
TYW3 tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) -1.98721
TBP TATA box binding protein -1.96222
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -1.93922
TRPM4 transient receptor potential cation channel, subfamily M, member 4 -1.91568
NFIA nuclear factor I/A -1.91442
LONP2 lon peptidase 2, peroxisomal -1.86938
ZBTB20 zinc finger and BTB domain containing 20 -1.86131
LGALS4 lectin, galactoside-binding, soluble, 4 -1.8183
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent -1.81083
MFSD6 major facilitator superfamily domain containing 6 -1.81025
SCAF8 SR-related CTD-associated factor 8 -1.80165
DIS3L DIS3 like exosome 3'-5' exoribonuclease -1.79425
TM4SF5 transmembrane 4 L six family member 5 -1.79247
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -1.76687
BPTF bromodomain PHD finger transcription factor -1.76192
TMCC3 transmembrane and coiled-coil domain family 3 -1.74988
LIPE lipase, hormone-sensitive -1.70383
PROSER1 proline and serine rich 1 -1.67225
THRSP thyroid hormone responsive -1.65369
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase -1.61122
EGFLAM EGF-like, fibronectin type III and laminin G domains -1.58904
UBA6 ubiquitin-like modifier activating enzyme 6 -1.58337
TMEM42 transmembrane protein 42 -1.58266
PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 -1.57066
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 -1.56509
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 -1.559
SETD6 SET domain containing 6 -1.54751
FAM98B family with sequence similarity 98, member B -1.53247
SHANK2 SH3 and multiple ankyrin repeat domains 2 -1.52972
SUZ12 SUZ12 polycomb repressive complex 2 subunit -1.52456
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 -1.51945
BLCAP bladder cancer associated protein -1.50988
SCMH1 sex comb on midleg homolog 1 (Drosophila) -1.489
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 -1.47991
MYLK3 myosin light chain kinase 3 -1.47211
VWA7 von Willebrand factor A domain containing 7 -1.47196
PSEN2 presenilin 2 -1.47184
ATG10 autophagy related 10 -1.4705
SLC4A3 solute carrier family 4 (anion exchanger), member 3 -1.43238
NUP153 nucleoporin 153kDa -1.42623
PEX11A peroxisomal biogenesis factor 11 alpha -1.42193
RICTOR RPTOR independent companion of MTOR, complex 2 -1.41752
ELAC1 elaC ribonuclease Z 1 -1.41299
NRD1 nardilysin (N-arginine dibasic convertase) -1.40972
PPP1R3A protein phosphatase 1, regulatory subunit 3A -1.40761
TBCEL tubulin folding cofactor E-like -1.40614
ZNF629 zinc finger protein 629 -1.40146
ZFYVE26 zinc finger, FYVE domain containing 26 -1.3996
PPM1K protein phosphatase, Mg2+/Mn2+ dependent, 1K -1.39367
FAM110C family with sequence similarity 110, member C -1.39273
C9ORF91 chromosome 9 open reading frame 91 -1.38133
TEPP testis, prostate and placenta expressed -1.38032
PDE4A phosphodiesterase 4A, cAMP-specific -1.37729
RBM24 RNA binding motif protein 24 -1.37324
C14ORF93 chromosome 14 open reading frame 93 -1.3618
AMY2A amylase, alpha 2A (pancreatic) -1.34796
SLC25A34 solute carrier family 25, member 34 -1.33703
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 -1.32985
ANO10 anoctamin 10 -1.32981
GATA6 GATA binding protein 6 -1.32785
PLAGL1 pleiomorphic adenoma gene-like 1 -1.32742
CCBL2 cysteine conjugate-beta lyase 2 -1.32493
TXNL1 thioredoxin-like 1 -1.3224
SNED1 sushi, nidogen and EGF-like domains 1 -1.31911
PNPT1 polyribonucleotide nucleotidyltransferase 1 -1.31572
COIL coilin -1.30645
ZCRB1 zinc finger CCHC-type and RNA binding motif 1 -1.30112
TPMT thiopurine S-methyltransferase -1.28487
TEK TEK tyrosine kinase, endothelial -1.28437
STK39 serine threonine kinase 39 -1.28328
ECHDC2 enoyl CoA hydratase domain containing 2 -1.28178
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -1.27737
PLIN2 perilipin 2 -1.276
BNC1 basonuclin 1 -1.27145
BCL2L11 BCL2-like 11 (apoptosis facilitator) -1.27125
PEX1 peroxisomal biogenesis factor 1 -1.26682
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) -1.26417
SLC35E4 solute carrier family 35, member E4 -1.26138
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -1.26095
ZNF512 zinc finger protein 512 -1.25756
KAT2B K(lysine) acetyltransferase 2B -1.2571
SLC25A42 solute carrier family 25, member 42 -1.25322
RBM15 RNA binding motif protein 15 -1.25225
IRAK1BP1 interleukin-1 receptor-associated kinase 1 binding protein 1 -1.25133
L2HGDH L-2-hydroxyglutarate dehydrogenase -1.24857
ZNF395 zinc finger protein 395 -1.24671
WAC WW domain containing adaptor with coiled-coil -1.2439
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 -1.24369
ZNF148 zinc finger protein 148 -1.2423
MTTP microsomal triglyceride transfer protein -1.24215
BCL9 B-cell CLL/lymphoma 9 -1.24185
ADGRL4 adhesion G protein-coupled receptor L4 -1.23705
EPC2 enhancer of polycomb homolog 2 (Drosophila) -1.23344
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -1.22845
POC1B POC1 centriolar protein B -1.22841
TRPC5 transient receptor potential cation channel, subfamily C, member 5 -1.22074
AKAP8 A kinase (PRKA) anchor protein 8 -1.22068
HEATR3 HEAT repeat containing 3 -1.21866
GABPA GA binding protein transcription factor, alpha subunit 60kDa -1.21812
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -1.20344
PLXNB1 plexin B1 -1.20265
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -1.19258
R3HDM2 R3H domain containing 2 -1.19255
KIAA2018 KIAA2018 -1.19038
MAOB monoamine oxidase B -1.1886
IL10RB interleukin 10 receptor, beta -1.18746
RXRB retinoid X receptor, beta -1.18609
SETD3 SET domain containing 3 -1.18374
PPP4R2 protein phosphatase 4, regulatory subunit 2 -1.18174
UBL3 ubiquitin-like 3 -1.17935
GATSL2 GATS protein-like 2 -1.1771
KANSL1L KAT8 regulatory NSL complex subunit 1-like -1.17449
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1 -1.17325
MARCH9 membrane-associated ring finger (C3HC4) 9 -1.17324
HECA headcase homolog (Drosophila) -1.17083
SAFB scaffold attachment factor B -1.16995
FMN1 formin 1 -1.16963
METTL15 methyltransferase like 15 -1.16871
C6ORF222 chromosome 6 open reading frame 222 -1.16837
ULK1 unc-51 like autophagy activating kinase 1 -1.16831
MAST2 microtubule associated serine/threonine kinase 2 -1.16646
PDE8B phosphodiesterase 8B -1.1649
CHD6 chromodomain helicase DNA binding protein 6 -1.16239
LYSMD3 LysM, putative peptidoglycan-binding, domain containing 3 -1.16165
WIZ widely interspaced zinc finger motifs -1.15967
MTM1 myotubularin 1 -1.15805
ZNF219 zinc finger protein 219 -1.15786
ZHX2 zinc fingers and homeoboxes 2 -1.15776
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 -1.15627
WNK2 WNK lysine deficient protein kinase 2 -1.156
HDAC2 histone deacetylase 2 -1.15569
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -1.15082
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 -1.14742
YBX2 Y box binding protein 2 -1.14724
SCHIP1 schwannomin interacting protein 1 -1.14426
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 -1.14425
IAPP islet amyloid polypeptide -1.14231
MLH3 mutL homolog 3 -1.14104
SCARF1 scavenger receptor class F, member 1 -1.13738
EGLN3 egl-9 family hypoxia-inducible factor 3 -1.13628
UBN2 ubinuclein 2 -1.13596
VLDLR very low density lipoprotein receptor -1.13538
PDE7A phosphodiesterase 7A -1.13235
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B -1.13217
MYH14 myosin, heavy chain 14, non-muscle -1.12589
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 -1.1226
FRYL FRY-like -1.12012
TNS1 tensin 1 -1.11858
METTL14 methyltransferase like 14 -1.11719
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 -1.11702
FAM168B family with sequence similarity 168, member B -1.11622
LRFN3 leucine rich repeat and fibronectin type III domain containing 3 -1.11603
MFAP3L microfibrillar-associated protein 3-like -1.11495
LENG8 leukocyte receptor cluster (LRC) member 8 -1.11432
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 -1.11272
TOB2 transducer of ERBB2, 2 -1.11259
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 -1.11251
FGA fibrinogen alpha chain -1.11181
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -1.11039
GLIS3 GLIS family zinc finger 3 -1.10861
PCMTD1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 -1.10854
MSI2 musashi RNA-binding protein 2 -1.10684
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase -1.10643
PBX1 pre-B-cell leukemia homeobox 1 -1.10465
ADGRF5 adhesion G protein-coupled receptor F5 -1.10144
IGFBP6 insulin-like growth factor binding protein 6 -1.10118
PODXL2 podocalyxin-like 2 -1.10064
GPATCH8 G patch domain containing 8 -1.09952
TNIK TRAF2 and NCK interacting kinase -1.09926
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium) -1.0988
UBR2 ubiquitin protein ligase E3 component n-recognin 2 -1.09804
TM4SF1 transmembrane 4 L six family member 1 -1.09784
TNRC6B trinucleotide repeat containing 6B -1.09553
AMOTL2 angiomotin like 2 -1.09387
LCOR ligand dependent nuclear receptor corepressor -1.09162
ZC3H8 zinc finger CCCH-type containing 8 -1.08897
AASDH aminoadipate-semialdehyde dehydrogenase -1.08805
TBC1D4 TBC1 domain family, member 4 -1.085
LAMA3 laminin, alpha 3 -1.07934
YY1 YY1 transcription factor -1.07594
CLCN3 chloride channel, voltage-sensitive 3 -1.0758
FGB fibrinogen beta chain -1.0753
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase -1.07233
EGLN1 egl-9 family hypoxia-inducible factor 1 -1.06896
CLK1 CDC-like kinase 1 -1.06686
PDPR pyruvate dehydrogenase phosphatase regulatory subunit -1.06574
ARID1B AT rich interactive domain 1B (SWI1-like) -1.06539
AQP4 aquaporin 4 -1.06334
FSTL4 follistatin-like 4 -1.0599
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -1.05959
SIK3 SIK family kinase 3 -1.05865
XPO4 exportin 4 -1.05803
DFNB31 deafness, autosomal recessive 31 -1.05738
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -1.05412
LZIC leucine zipper and CTNNBIP1 domain containing -1.05383
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 -1.05308
DENND3 DENN/MADD domain containing 3 -1.05212
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) -1.05145
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -1.05113
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) -1.05041
NEK7 NIMA-related kinase 7 -1.04227
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 -1.04118
ENY2 enhancer of yellow 2 homolog (Drosophila) -1.04001
FMO4 flavin containing monooxygenase 4 -1.03932
GIGYF1 GRB10 interacting GYF protein 1 -1.03738
DUSP10 dual specificity phosphatase 10 -1.03712
GRIK5 glutamate receptor, ionotropic, kainate 5 -1.03641
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein -1.0362
JMY junction mediating and regulatory protein, p53 cofactor -1.03308
MED1 mediator complex subunit 1 -1.03198
CPEB3 cytoplasmic polyadenylation element binding protein 3 -1.02985
VWA8 von Willebrand factor A domain containing 8 -1.02936
MYOCD myocardin -1.02717
ACSS1 acyl-CoA synthetase short-chain family member 1 -1.02632
KLF15 Kruppel-like factor 15 -1.0231
C21ORF2 chromosome 21 open reading frame 2 -1.01858
NCOA1 nuclear receptor coactivator 1 -1.01616
MLYCD malonyl-CoA decarboxylase -1.0159
HIST1H3D histone cluster 1, H3d -1.01505
LYSMD4 LysM, putative peptidoglycan-binding, domain containing 4 -1.01181
BEND5 BEN domain containing 5 -1.01058
BID BH3 interacting domain death agonist -1.00858
CCPG1 cell cycle progression 1 -1.0068
ATN1 atrophin 1 -1.00615
POLR3GL polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like -1.0038
FITM2 fat storage-inducing transmembrane protein 2 -1.00353
VEZF1 vascular endothelial zinc finger 1 -1.0029
CNGB3 cyclic nucleotide gated channel beta 3 -1.00103
GKAP1 G kinase anchoring protein 1 -1.00095
TRIM39 tripartite motif containing 39 -1.00093
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) -0.999972
DENND4C DENN/MADD domain containing 4C -0.99969
EPB41 erythrocyte membrane protein band 4.1 -0.999679
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit -0.998667
SLC12A9 solute carrier family 12, member 9 -0.998565
ADNP2 ADNP homeobox 2 -0.997284
ARMC1 armadillo repeat containing 1 -0.994479
ECH1 enoyl CoA hydratase 1, peroxisomal -0.992186
TMEM170B transmembrane protein 170B -0.990419
ACSL6 acyl-CoA synthetase long-chain family member 6 -0.989405
PTGFR prostaglandin F receptor (FP) -0.988891
GATA2 GATA binding protein 2 -0.986663
CREG1 cellular repressor of E1A-stimulated genes 1 -0.984429
XPOT exportin, tRNA -0.982707
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -0.981441
MAPK6 mitogen-activated protein kinase 6 -0.981402
CLK4 CDC-like kinase 4 -0.980887
AKAP3 A kinase (PRKA) anchor protein 3 -0.978229
ECE1 endothelin converting enzyme 1 -0.974783
FAM126A family with sequence similarity 126, member A -0.974648
ADGRL1 adhesion G protein-coupled receptor L1 -0.974119
TRAF3IP2 TRAF3 interacting protein 2 -0.973725
C6ORF203 chromosome 6 open reading frame 203 -0.9728
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 -0.970948
ZNF639 zinc finger protein 639 -0.969954
NXF1 nuclear RNA export factor 1 -0.969534
ZMYM2 zinc finger, MYM-type 2 -0.969313
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa -0.969157
DTWD2 DTW domain containing 2 -0.968272
BRD8 bromodomain containing 8 -0.967164
FGD4 FYVE, RhoGEF and PH domain containing 4 -0.965643
DCAF4 DDB1 and CUL4 associated factor 4 -0.964767
GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 -0.964242
KDM4A lysine (K)-specific demethylase 4A -0.962977
RNF10 ring finger protein 10 -0.961194
AKAP10 A kinase (PRKA) anchor protein 10 -0.961065
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.960076
ADK adenosine kinase -0.958746
OXSR1 oxidative stress responsive 1 -0.958344
DIXDC1 DIX domain containing 1 -0.956643
KIF18A kinesin family member 18A -0.952889
PRSS55 protease, serine, 55 -0.952617
OTUD7B OTU deubiquitinase 7B -0.952149
PARP11 poly (ADP-ribose) polymerase family, member 11 -0.952138
CRYBG3 beta-gamma crystallin domain containing 3 -0.951773
SGOL2 shugoshin-like 2 (S. pombe) -0.950059
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) -0.9497
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 -0.949406
MFSD3 major facilitator superfamily domain containing 3 -0.948976
SUSD3 sushi domain containing 3 -0.94617
DUSP18 dual specificity phosphatase 18 -0.944557
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 -0.942989
GPR162 G protein-coupled receptor 162 -0.942786
GRAMD4 GRAM domain containing 4 -0.941307
MRPL16 mitochondrial ribosomal protein L16 -0.94057
PPP6R3 protein phosphatase 6, regulatory subunit 3 -0.938187
MPHOSPH9 M-phase phosphoprotein 9 -0.937837
ZNF865 zinc finger protein 865 -0.936011
OCIAD1 OCIA domain containing 1 -0.935412
DMPK dystrophia myotonica-protein kinase -0.934843
RB1CC1 RB1-inducible coiled-coil 1 -0.933598
ZNF280B zinc finger protein 280B -0.933224
C5ORF63 chromosome 5 open reading frame 63 -0.931747