Cardiac Failure_Myocardial tissue_GSE1988 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE1988
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Genes

600 genes differentially expressed during Cardiac Failure_Myocardial tissue_GSE1988 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic) 5.27837
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 3.83409
ARRB2 arrestin, beta 2 3.75728
CSDE1 cold shock domain containing E1, RNA-binding 3.21164
TMBIM1 transmembrane BAX inhibitor motif containing 1 3.0025
OSMR oncostatin M receptor 2.96877
SHCBP1 SHC SH2-domain binding protein 1 2.95829
BASP1 brain abundant, membrane attached signal protein 1 2.91827
SHROOM3 shroom family member 3 2.90543
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 2.77763
PPP6R2 protein phosphatase 6, regulatory subunit 2 2.68295
PDC phosducin 2.6498
GMCL1 germ cell-less, spermatogenesis associated 1 2.5206
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 2.49619
BMP1 bone morphogenetic protein 1 2.48748
SPATA5 spermatogenesis associated 5 2.3753
PTPN11 protein tyrosine phosphatase, non-receptor type 11 2.29234
IL1R1 interleukin 1 receptor, type I 2.26394
UGCG UDP-glucose ceramide glucosyltransferase 2.24058
SLC38A4 solute carrier family 38, member 4 2.22385
C2ORF71 chromosome 2 open reading frame 71 2.21631
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 2.19485
ZCCHC6 zinc finger, CCHC domain containing 6 2.17637
GOPC golgi-associated PDZ and coiled-coil motif containing 2.12693
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 2.1221
ELOVL1 ELOVL fatty acid elongase 1 2.10279
ZBTB7B zinc finger and BTB domain containing 7B 2.07675
DUSP2 dual specificity phosphatase 2 2.05552
IL5RA interleukin 5 receptor, alpha 2.04887
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 2.04234
TPD52 tumor protein D52 2.0349
LIMA1 LIM domain and actin binding 1 2.0221
TCERG1 transcription elongation regulator 1 2.02104
FES FES proto-oncogene, tyrosine kinase 2.01361
IPO5 importin 5 1.99953
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 1.99228
CDCP1 CUB domain containing protein 1 1.98993
ASPRV1 aspartic peptidase, retroviral-like 1 1.95571
TMEM27 transmembrane protein 27 1.95123
PLCZ1 phospholipase C, zeta 1 1.94228
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 1.94011
TMEM176A transmembrane protein 176A 1.88508
ADGRV1 adhesion G protein-coupled receptor V1 1.88106
KIFC1 kinesin family member C1 1.88074
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 1.87219
TMEM71 transmembrane protein 71 1.86398
MYOZ2 myozenin 2 1.86214
CSF1R colony stimulating factor 1 receptor 1.85847
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 1.83779
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 1.82729
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 1.82243
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 1.76533
HNF4G hepatocyte nuclear factor 4, gamma 1.76506
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 1.70755
RTKN2 rhotekin 2 1.69815
SLC39A6 solute carrier family 39 (zinc transporter), member 6 1.69793
XCR1 chemokine (C motif) receptor 1 1.69154
NPR3 natriuretic peptide receptor 3 1.68757
RPS17 ribosomal protein S17 1.675
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 1.65853
TLN1 talin 1 1.65343
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 1.64778
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.64747
MAEA macrophage erythroblast attacher 1.64428
ATMIN ATM interactor 1.63631
PARP16 poly (ADP-ribose) polymerase family, member 16 1.6261
GRIP1 glutamate receptor interacting protein 1 1.62025
BTG2 BTG family, member 2 1.61926
IFFO1 intermediate filament family orphan 1 1.61756
CCDC120 coiled-coil domain containing 120 1.61516
TRIM37 tripartite motif containing 37 1.60265
FAM110A family with sequence similarity 110, member A 1.58348
SMAP1 small ArfGAP 1 1.56203
PERP PERP, TP53 apoptosis effector 1.55001
BAG4 BCL2-associated athanogene 4 1.54667
TSPAN8 tetraspanin 8 1.53027
HAVCR2 hepatitis A virus cellular receptor 2 1.52459
IL7 interleukin 7 1.51877
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 1.51681
WNT7A wingless-type MMTV integration site family, member 7A 1.50972
ACVR1C activin A receptor, type IC 1.50095
TEX11 testis expressed 11 1.5009
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8 1.49916
UBE2H ubiquitin-conjugating enzyme E2H 1.49424
SBF2 SET binding factor 2 1.49297
FIGF c-fos induced growth factor (vascular endothelial growth factor D) 1.48647
ZNF773 zinc finger protein 773 1.4844
IRF9 interferon regulatory factor 9 1.47994
AAAS achalasia, adrenocortical insufficiency, alacrimia 1.47563
ASS1 argininosuccinate synthase 1 1.4659
ZNF106 zinc finger protein 106 1.46555
CHMP3 charged multivesicular body protein 3 1.46261
IQGAP2 IQ motif containing GTPase activating protein 2 1.45693
SSRP1 structure specific recognition protein 1 1.45166
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 1.4508
VSTM2A V-set and transmembrane domain containing 2A 1.44944
DMP1 dentin matrix acidic phosphoprotein 1 1.44901
ZCCHC9 zinc finger, CCHC domain containing 9 1.44625
ZWINT ZW10 interacting kinetochore protein 1.44041
PA2G4 proliferation-associated 2G4, 38kDa 1.43201
SEC24B SEC24 family member B 1.42994
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.42085
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 1.41396
BID BH3 interacting domain death agonist 1.40962
NUDCD2 NudC domain containing 2 1.40763
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 1.39804
FAM26E family with sequence similarity 26, member E 1.39573
EXOC1 exocyst complex component 1 1.39217
KDM2B lysine (K)-specific demethylase 2B 1.3913
VAX1 ventral anterior homeobox 1 1.39072
ETF1 eukaryotic translation termination factor 1 1.38989
HEATR1 HEAT repeat containing 1 1.38811
SEPT5 septin 5 1.38725
DEPDC7 DEP domain containing 7 1.3865
FBXO16 F-box protein 16 1.38127
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.37825
CHGB chromogranin B 1.37697
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta 1.37307
LOXL4 lysyl oxidase-like 4 1.37303
RAB7B RAB7B, member RAS oncogene family 1.37242
CORO1A coronin, actin binding protein, 1A 1.36875
TMEM106A transmembrane protein 106A 1.36673
UBE2D3 ubiquitin-conjugating enzyme E2D 3 1.36581
EPB41L1 erythrocyte membrane protein band 4.1-like 1 1.36509
RAD51 RAD51 recombinase 1.35803
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 1.35664
NEUROD1 neuronal differentiation 1 1.35105
AP3B2 adaptor-related protein complex 3, beta 2 subunit 1.35089
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 1.3446
AGBL3 ATP/GTP binding protein-like 3 1.34425
SPON2 spondin 2, extracellular matrix protein 1.33934
SEPT8 septin 8 1.33736
SSTR2 somatostatin receptor 2 1.3308
ADGRA2 adhesion G protein-coupled receptor A2 1.32308
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 1.32027
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.31652
MPG N-methylpurine-DNA glycosylase 1.3104
MR1 major histocompatibility complex, class I-related 1.30216
C14ORF79 chromosome 14 open reading frame 79 1.29872
TMC1 transmembrane channel-like 1 1.29594
DGKG diacylglycerol kinase, gamma 90kDa 1.29028
ITSN1 intersectin 1 (SH3 domain protein) 1.28956
CORO2B coronin, actin binding protein, 2B 1.28938
CHODL chondrolectin 1.28644
RAB38 RAB38, member RAS oncogene family 1.28505
FKBP9 FK506 binding protein 9, 63 kDa 1.28384
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 1.28022
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 1.27244
SLIT3 slit homolog 3 (Drosophila) 1.2602
FXYD5 FXYD domain containing ion transport regulator 5 1.25833
SMC1B structural maintenance of chromosomes 1B 1.25619
EFS embryonal Fyn-associated substrate 1.25297
AHNAK AHNAK nucleoprotein 1.25251
COL18A1 collagen, type XVIII, alpha 1 1.24948
WDFY1 WD repeat and FYVE domain containing 1 1.24263
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.23845
TUBB3 tubulin, beta 3 class III 1.23821
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10 1.23594
FOXG1 forkhead box G1 1.22797
C1QL3 complement component 1, q subcomponent-like 3 1.22583
FLT4 fms-related tyrosine kinase 4 1.21315
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 1.20376
RAMP3 receptor (G protein-coupled) activity modifying protein 3 1.20319
GNA13 guanine nucleotide binding protein (G protein), alpha 13 1.20161
SIGMAR1 sigma non-opioid intracellular receptor 1 1.20112
RPS5 ribosomal protein S5 1.19883
DUSP22 dual specificity phosphatase 22 1.19857
STAB1 stabilin 1 1.19708
TMEM158 transmembrane protein 158 (gene/pseudogene) 1.19202
SKIL SKI-like proto-oncogene 1.19191
CD47 CD47 molecule 1.18807
EHD4 EH-domain containing 4 1.18634
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.18473
KRT80 keratin 80, type II 1.18348
MYO9B myosin IXB 1.18258
CA10 carbonic anhydrase X 1.182
CSK c-src tyrosine kinase 1.17755
PTPRG protein tyrosine phosphatase, receptor type, G 1.17132
RAB31 RAB31, member RAS oncogene family 1.17124
MBNL3 muscleblind-like splicing regulator 3 1.17027
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 1.16945
METAP2 methionyl aminopeptidase 2 1.16867
C1QTNF1 C1q and tumor necrosis factor related protein 1 1.16549
NT5DC3 5'-nucleotidase domain containing 3 1.15422
SCN8A sodium channel, voltage gated, type VIII alpha subunit 1.15356
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 1.15176
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 1.14816
CXCR6 chemokine (C-X-C motif) receptor 6 1.13855
CNR1 cannabinoid receptor 1 (brain) 1.13774
SFXN3 sideroflexin 3 1.13268
ZC3H10 zinc finger CCCH-type containing 10 1.1323
HOXA4 homeobox A4 1.13061
AASS aminoadipate-semialdehyde synthase 1.12528
SAR1A secretion associated, Ras related GTPase 1A 1.12446
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 1.12311
OLFM1 olfactomedin 1 1.12002
CD27 CD27 molecule 1.11859
TMEM183A transmembrane protein 183A 1.1175
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 1.11666
ANKRD61 ankyrin repeat domain 61 1.11563
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1 1.11407
CLDN23 claudin 23 1.11248
UBE2K ubiquitin-conjugating enzyme E2K 1.11033
GIPC2 GIPC PDZ domain containing family, member 2 1.11029
AGER advanced glycosylation end product-specific receptor 1.10768
CENPM centromere protein M 1.10586
CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) 1.10515
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) 1.1043
RNF34 ring finger protein 34, E3 ubiquitin protein ligase 1.10372
MYCBPAP MYCBP associated protein 1.10249
MAP2K7 mitogen-activated protein kinase kinase 7 1.10193
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 1.09881
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 1.09262
TXNRD1 thioredoxin reductase 1 1.09032
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 1.08453
OIT3 oncoprotein induced transcript 3 1.07928
CHD1 chromodomain helicase DNA binding protein 1 1.079
ZBTB46 zinc finger and BTB domain containing 46 1.07852
TRIM24 tripartite motif containing 24 1.07852
IMP4 IMP4, U3 small nucleolar ribonucleoprotein 1.07756
MPDZ multiple PDZ domain protein 1.07507
CD163 CD163 molecule 1.07385
SOWAHA sosondowah ankyrin repeat domain family member A 1.07251
LUC7L LUC7-like (S. cerevisiae) 1.0682
MYO6 myosin VI 1.0649
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 1.06343
METTL6 methyltransferase like 6 1.06125
UBXN2A UBX domain protein 2A 1.06061
NKAP NFKB activating protein 1.06031
SMS spermine synthase 1.06009
LCOR ligand dependent nuclear receptor corepressor 1.0588
NMT1 N-myristoyltransferase 1 1.05762
HIST1H1C histone cluster 1, H1c 1.05699
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.05593
HOXB8 homeobox B8 1.05562
INO80C INO80 complex subunit C 1.05481
RHPN2 rhophilin, Rho GTPase binding protein 2 1.05311
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 1.04366
TRIM7 tripartite motif containing 7 1.04327
PCDHB8 protocadherin beta 8 1.04305
PLA2G2E phospholipase A2, group IIE 1.04142
CNOT7 CCR4-NOT transcription complex, subunit 7 1.03985
NOP16 NOP16 nucleolar protein 1.03859
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 1.03697
CLINT1 clathrin interactor 1 1.03682
MLPH melanophilin 1.03577
VEGFC vascular endothelial growth factor C 1.03354
GGNBP2 gametogenetin binding protein 2 1.03245
PTRH1 peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae) 1.03081
ZDHHC2 zinc finger, DHHC-type containing 2 1.02893
UBN1 ubinuclein 1 1.0276
ICAM1 intercellular adhesion molecule 1 1.02305
HEYL hes-related family bHLH transcription factor with YRPW motif-like 1.02002
AMOT angiomotin 1.01982
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 1.01922
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 1.01554
CALN1 calneuron 1 1.0155
MIB1 mindbomb E3 ubiquitin protein ligase 1 1.01464
TTC39B tetratricopeptide repeat domain 39B 1.01401
NFAM1 NFAT activating protein with ITAM motif 1 1.01
TJP2 tight junction protein 2 1.00944
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 1.00827
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae) 1.00767
PAK1IP1 PAK1 interacting protein 1 1.00634
SEC23IP SEC23 interacting protein 1.00616
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa 1.00323
TNNC2 troponin C type 2 (fast) 1.0007
MNS1 meiosis-specific nuclear structural 1 1.00069
CDV3 CDV3 homolog (mouse) 1.00062
TMEM176B transmembrane protein 176B 0.999839
GNG12 guanine nucleotide binding protein (G protein), gamma 12 0.998688
GALE UDP-galactose-4-epimerase 0.997221
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 0.997131
PLS1 plastin 1 0.995407
DESI2 desumoylating isopeptidase 2 0.994979
ASCL2 achaete-scute family bHLH transcription factor 2 0.99245
ANAPC1 anaphase promoting complex subunit 1 0.989332
TYK2 tyrosine kinase 2 0.989057
LETMD1 LETM1 domain containing 1 0.988754
MRPL33 mitochondrial ribosomal protein L33 0.98809
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) 0.986952
ITSN2 intersectin 2 0.986691
MMP1 matrix metallopeptidase 1 0.983355
TNF tumor necrosis factor 0.981877
SYNE1 spectrin repeat containing, nuclear envelope 1 0.980486
IDE insulin-degrading enzyme 0.979477
PWP1 PWP1 homolog (S. cerevisiae) 0.978148
SPHK1 sphingosine kinase 1 0.97733
RPL8 ribosomal protein L8 0.977303
STAR steroidogenic acute regulatory protein 0.976705
CLEC11A C-type lectin domain family 11, member A 0.975378
TCEA1 transcription elongation factor A (SII), 1 0.96777
KIFAP3 kinesin-associated protein 3 0.967669
RIOK3 RIO kinase 3 0.966513
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) 0.966465
TULP4 tubby like protein 4 0.966082
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 0.964607
SCAF8 SR-related CTD-associated factor 8 0.962821
FABP9 fatty acid binding protein 9, testis 0.962159
ARSI arylsulfatase family, member I 0.961975

decreased expression

Symbol Name Standardized Value
OTC ornithine carbamoyltransferase -4.11746
CDH4 cadherin 4, type 1, R-cadherin (retinal) -3.88786
DCBLD1 discoidin, CUB and LCCL domain containing 1 -3.31422
BET1L Bet1 golgi vesicular membrane trafficking protein-like -3.293
PKDREJ polycystin (PKD) family receptor for egg jelly -3.2746
OR6A2 olfactory receptor, family 6, subfamily A, member 2 -3.1308
C5ORF52 chromosome 5 open reading frame 52 -3.04467
RNF32 ring finger protein 32 -3.00861
RABL6 RAB, member RAS oncogene family-like 6 -2.9713
TMUB1 transmembrane and ubiquitin-like domain containing 1 -2.9363
CUX2 cut-like homeobox 2 -2.91107
SPIN4 spindlin family, member 4 -2.87124
MYO19 myosin XIX -2.86374
EFNB2 ephrin-B2 -2.85953
MYB v-myb avian myeloblastosis viral oncogene homolog -2.76713
GANAB glucosidase, alpha; neutral AB -2.69994
RNF121 ring finger protein 121 -2.68882
HACD2 3-hydroxyacyl-CoA dehydratase 2 -2.61449
GJB3 gap junction protein, beta 3, 31kDa -2.55587
MDH1 malate dehydrogenase 1, NAD (soluble) -2.48534
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa -2.47901
MED28 mediator complex subunit 28 -2.44393
CDK12 cyclin-dependent kinase 12 -2.42798
HINT2 histidine triad nucleotide binding protein 2 -2.40811
TRIB3 tribbles pseudokinase 3 -2.40127
EMC6 ER membrane protein complex subunit 6 -2.37239
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) -2.32917
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa -2.32488
VWA8 von Willebrand factor A domain containing 8 -2.32471
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase -2.31957
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa -2.29149
RNF220 ring finger protein 220 -2.29138
CACNB3 calcium channel, voltage-dependent, beta 3 subunit -2.23469
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 -2.21603
NTM neurotrimin -2.19941
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -2.19408
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -2.19072
XCL1 chemokine (C motif) ligand 1 -2.18157
NKX1-2 NK1 homeobox 2 -2.1237
SIX4 SIX homeobox 4 -2.11442
MYO15A myosin XVA -2.11408
CTR9 CTR9, Paf1/RNA polymerase II complex component -2.0968
ERP44 endoplasmic reticulum protein 44 -2.08834
HS1BP3 HCLS1 binding protein 3 -2.0635
USP36 ubiquitin specific peptidase 36 -2.06176
RPS15A ribosomal protein S15a -2.05235
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -2.04291
FNDC4 fibronectin type III domain containing 4 -2.03385
FCRL1 Fc receptor-like 1 -2.02647
GID4 GID complex subunit 4 -2.01471
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -2.00825
APC2 adenomatosis polyposis coli 2 -1.99299
PTS 6-pyruvoyltetrahydropterin synthase -1.98355
CSNK1E casein kinase 1, epsilon -1.97849
FADS2 fatty acid desaturase 2 -1.96203
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 -1.96095
IMP3 IMP3, U3 small nucleolar ribonucleoprotein -1.95711
ROGDI rogdi homolog (Drosophila) -1.9472
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 -1.93935
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) -1.93144
UBXN10 UBX domain protein 10 -1.92473
ZIK1 zinc finger protein interacting with K protein 1 -1.92029
EFNA4 ephrin-A4 -1.91729
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 -1.91413
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) -1.89967
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F -1.88551
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 -1.87116
GSTM4 glutathione S-transferase mu 4 -1.86263
POF1B premature ovarian failure, 1B -1.85415
MRPS14 mitochondrial ribosomal protein S14 -1.85005
OLFM3 olfactomedin 3 -1.8494
ANKRD24 ankyrin repeat domain 24 -1.83086
PIP prolactin-induced protein -1.8282
SNX22 sorting nexin 22 -1.8186
MTX1 metaxin 1 -1.81239
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase -1.81031
PKD2L2 polycystic kidney disease 2-like 2 -1.80733
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -1.80088
TSPAN3 tetraspanin 3 -1.78553
METTL21A methyltransferase like 21A -1.77896
FANCA Fanconi anemia, complementation group A -1.77578
RPS10 ribosomal protein S10 -1.77055
CYHR1 cysteine/histidine-rich 1 -1.75626
UQCRHL ubiquinol-cytochrome c reductase hinge protein-like -1.75539
EXD2 exonuclease 3'-5' domain containing 2 -1.754
DCAF4 DDB1 and CUL4 associated factor 4 -1.73425
RND2 Rho family GTPase 2 -1.72424
TARBP2 TAR (HIV-1) RNA binding protein 2 -1.72421
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 -1.72168
PRND prion protein 2 (dublet) -1.71162
PDHB pyruvate dehydrogenase (lipoamide) beta -1.70984
PARD6G par-6 family cell polarity regulator gamma -1.70628
NARF nuclear prelamin A recognition factor -1.70553
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 -1.70425
MACROD2 MACRO domain containing 2 -1.70143
STK31 serine/threonine kinase 31 -1.69849
NCAPG2 non-SMC condensin II complex, subunit G2 -1.69683
PGLYRP2 peptidoglycan recognition protein 2 -1.68843
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -1.68682
NADK NAD kinase -1.68672
SNX29 sorting nexin 29 -1.68305
HRH2 histamine receptor H2 -1.67587
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -1.6739
WDR33 WD repeat domain 33 -1.67145
PDCL2 phosducin-like 2 -1.66572
AAGAB alpha- and gamma-adaptin binding protein -1.66403
PLCB4 phospholipase C, beta 4 -1.65786
TBL2 transducin (beta)-like 2 -1.64565
C7ORF55 chromosome 7 open reading frame 55 -1.63666
COX15 cytochrome c oxidase assembly homolog 15 (yeast) -1.63393
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -1.63371
ITGB7 integrin, beta 7 -1.62908
SNAI2 snail family zinc finger 2 -1.62882
ADCK3 aarF domain containing kinase 3 -1.61558
MRPS2 mitochondrial ribosomal protein S2 -1.61377
TMEM45B transmembrane protein 45B -1.61285
REPIN1 replication initiator 1 -1.60728
SIVA1 SIVA1, apoptosis-inducing factor -1.60609
ACPP acid phosphatase, prostate -1.60473
AP1S1 adaptor-related protein complex 1, sigma 1 subunit -1.60239
TRAPPC2 trafficking protein particle complex 2 -1.60175
KIRREL kin of IRRE like (Drosophila) -1.60147
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 -1.60059
THOC7 THO complex 7 -1.59142
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -1.58755
TP63 tumor protein p63 -1.58352
TNRC6B trinucleotide repeat containing 6B -1.57667
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -1.57131
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 -1.56955
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) -1.56878
EMILIN3 elastin microfibril interfacer 3 -1.56605
COQ10A coenzyme Q10 homolog A (S. cerevisiae) -1.56487
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor -1.56438
QPRT quinolinate phosphoribosyltransferase -1.56207
PLEKHA5 pleckstrin homology domain containing, family A member 5 -1.56152
CRYBA4 crystallin, beta A4 -1.5476
ZBTB25 zinc finger and BTB domain containing 25 -1.54421
CBX1 chromobox homolog 1 -1.54195
SLC35E4 solute carrier family 35, member E4 -1.54078
ARFIP2 ADP-ribosylation factor interacting protein 2 -1.5392
RHBDD3 rhomboid domain containing 3 -1.53659
PLXNA1 plexin A1 -1.52714
TSPAN5 tetraspanin 5 -1.52483
IL17RB interleukin 17 receptor B -1.52421
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) -1.5239
HAUS4 HAUS augmin-like complex, subunit 4 -1.52094
URM1 ubiquitin related modifier 1 -1.52004
COQ4 coenzyme Q4 -1.51993
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 -1.51338
FBLIM1 filamin binding LIM protein 1 -1.50818
CAMLG calcium modulating ligand -1.49591
METAP1D methionyl aminopeptidase type 1D (mitochondrial) -1.49395
RNF41 ring finger protein 41, E3 ubiquitin protein ligase -1.49185
EXOSC4 exosome component 4 -1.48802
CPOX coproporphyrinogen oxidase -1.48735
PPCDC phosphopantothenoylcysteine decarboxylase -1.4861
BMP2 bone morphogenetic protein 2 -1.48441
IL6 interleukin 6 -1.48375
USMG5 up-regulated during skeletal muscle growth 5 homolog (mouse) -1.48117
EFNB1 ephrin-B1 -1.47783
DAPK2 death-associated protein kinase 2 -1.47404
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 -1.47322
ZNF212 zinc finger protein 212 -1.47004
LAMC3 laminin, gamma 3 -1.46748
AGK acylglycerol kinase -1.46605
MED29 mediator complex subunit 29 -1.4623
SPRR3 small proline-rich protein 3 -1.46077
NUDT16L1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 -1.4589
VGLL4 vestigial-like family member 4 -1.45718
NEK1 NIMA-related kinase 1 -1.4527
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa -1.44969
TMPRSS4 transmembrane protease, serine 4 -1.44856
PBX4 pre-B-cell leukemia homeobox 4 -1.44808
XYLT2 xylosyltransferase II -1.44708
KHK ketohexokinase (fructokinase) -1.4467
GALM galactose mutarotase (aldose 1-epimerase) -1.44228
GEMIN8 gem (nuclear organelle) associated protein 8 -1.42608
NAP1L3 nucleosome assembly protein 1-like 3 -1.42388
SPAG4 sperm associated antigen 4 -1.41953
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -1.41502
DOLK dolichol kinase -1.41428
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 -1.41351
RBKS ribokinase -1.40606
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 -1.40588
TSHZ1 teashirt zinc finger homeobox 1 -1.4018
FOXK2 forkhead box K2 -1.39615
FOXD1 forkhead box D1 -1.38412
NRBP1 nuclear receptor binding protein 1 -1.38203
DNAJB8 DnaJ (Hsp40) homolog, subfamily B, member 8 -1.38118
CLASP2 cytoplasmic linker associated protein 2 -1.3673
TOM1L1 target of myb1 (chicken)-like 1 -1.36637
MYNN myoneurin -1.36608
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -1.36363
HOXA1 homeobox A1 -1.36349
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 -1.36311
GUCA2B guanylate cyclase activator 2B (uroguanylin) -1.36284
TRIM46 tripartite motif containing 46 -1.36159
APOA5 apolipoprotein A-V -1.35918
TRAPPC6A trafficking protein particle complex 6A -1.35486
ZNF717 zinc finger protein 717 -1.3544
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -1.35365
SCAND1 SCAN domain containing 1 -1.35281
ADRB1 adrenoceptor beta 1 -1.35037
EPN3 epsin 3 -1.34531
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) -1.34494
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa -1.33793
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) -1.32924
PHOX2A paired-like homeobox 2a -1.32866
PEX14 peroxisomal biogenesis factor 14 -1.32846
IFT140 intraflagellar transport 140 -1.32841
ACAT1 acetyl-CoA acetyltransferase 1 -1.32608
SHISA2 shisa family member 2 -1.32455
RGS7 regulator of G-protein signaling 7 -1.32336
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) -1.32293
IFNB1 interferon, beta 1, fibroblast -1.31459
CENPV centromere protein V -1.31089
WFDC1 WAP four-disulfide core domain 1 -1.30984
KAT2A K(lysine) acetyltransferase 2A -1.3071
MRPL11 mitochondrial ribosomal protein L11 -1.29652
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -1.29599
AUH AU RNA binding protein/enoyl-CoA hydratase -1.28639
FOXM1 forkhead box M1 -1.2845
SOX12 SRY (sex determining region Y)-box 12 -1.28366
PDCD1LG2 programmed cell death 1 ligand 2 -1.28171
PECR peroxisomal trans-2-enoyl-CoA reductase -1.27697
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -1.27562
SIDT1 SID1 transmembrane family, member 1 -1.27525
CCDC159 coiled-coil domain containing 159 -1.27327
SPATA19 spermatogenesis associated 19 -1.27114
RAB27B RAB27B, member RAS oncogene family -1.27107
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B -1.2686
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa -1.266
PSPN persephin -1.26434
SPRY2 sprouty homolog 2 (Drosophila) -1.26303
SPO11 SPO11 meiotic protein covalently bound to DSB -1.26159
DVL1 dishevelled segment polarity protein 1 -1.26114
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 -1.2605
TGS1 trimethylguanosine synthase 1 -1.25985
FAM161A family with sequence similarity 161, member A -1.25893
G0S2 G0/G1 switch 2 -1.25527
CDK2 cyclin-dependent kinase 2 -1.2525
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI -1.24974
SUCLG1 succinate-CoA ligase, alpha subunit -1.24807
ESR2 estrogen receptor 2 (ER beta) -1.24471
CHEK1 checkpoint kinase 1 -1.24322
CTRL chymotrypsin-like -1.24296
CTNNA2 catenin (cadherin-associated protein), alpha 2 -1.24284
OGG1 8-oxoguanine DNA glycosylase -1.24173
ADORA2A adenosine A2a receptor -1.23859
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha -1.23834
NKX2-6 NK2 homeobox 6 -1.23644
RPS21 ribosomal protein S21 -1.23248
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -1.23038
TMPRSS3 transmembrane protease, serine 3 -1.22845
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -1.22706
NPY2R neuropeptide Y receptor Y2 -1.22563
RCVRN recoverin -1.22247
ZDHHC1 zinc finger, DHHC-type containing 1 -1.222
GSC goosecoid homeobox -1.22073
FAM89A family with sequence similarity 89, member A -1.2168
SIT1 signaling threshold regulating transmembrane adaptor 1 -1.21604
METRN meteorin, glial cell differentiation regulator -1.21455
ACOT8 acyl-CoA thioesterase 8 -1.21105
POU6F1 POU class 6 homeobox 1 -1.21093
HDAC7 histone deacetylase 7 -1.21081
DNER delta/notch-like EGF repeat containing -1.20608
CDC26 cell division cycle 26 -1.20598
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2) -1.20565
FBXO43 F-box protein 43 -1.20393
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha -1.20373
VIPR2 vasoactive intestinal peptide receptor 2 -1.20138
TMEM82 transmembrane protein 82 -1.20037
CD300A CD300a molecule -1.19556
AQP7 aquaporin 7 -1.19537
RUNX3 runt-related transcription factor 3 -1.18913
HEATR5B HEAT repeat containing 5B -1.18453
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -1.18442
C21ORF59 chromosome 21 open reading frame 59 -1.1831
MSL3 male-specific lethal 3 homolog (Drosophila) -1.18278
CD276 CD276 molecule -1.18079
ZFAND2B zinc finger, AN1-type domain 2B -1.18077
THOC6 THO complex 6 -1.17998
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 -1.17959
KRT77 keratin 77, type II -1.17415
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -1.17157
TM2D1 TM2 domain containing 1 -1.16782
MED1 mediator complex subunit 1 -1.1664
SAA1 serum amyloid A1 -1.16494
NMB neuromedin B -1.16131
SCNN1B sodium channel, non voltage gated 1 beta subunit -1.16117
OPTC opticin -1.16031
EPHB2 EPH receptor B2 -1.15981
POLR1C polymerase (RNA) I polypeptide C, 30kDa -1.15462
IL12RB1 interleukin 12 receptor, beta 1 -1.15331
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C -1.15206
RPL38 ribosomal protein L38 -1.14682
UBE2A ubiquitin-conjugating enzyme E2A -1.14608
PDE7B phosphodiesterase 7B -1.14593
ZFP57 ZFP57 zinc finger protein -1.14469
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -1.14451