Carcinoma, Large Cell Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

74 genes associated with the Carcinoma, Large Cell phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALK anaplastic lymphoma receptor tyrosine kinase
APC adenomatous polyposis coli
BRAF B-Raf proto-oncogene, serine/threonine kinase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CLPTM1L CLPTM1-like
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
EGFR epidermal growth factor receptor
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB4 erb-b2 receptor tyrosine kinase 4
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC5 excision repair cross-complementation group 5
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FOS FBJ murine osteosarcoma viral oncogene homolog
GCLC glutamate-cysteine ligase, catalytic subunit
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HYKK hydroxylysine kinase
IGF1R insulin-like growth factor 1 receptor
IGF2R insulin-like growth factor 2 receptor
IL10 interleukin 10
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL4 interleukin 4
JUN jun proto-oncogene
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMA5 laminin, alpha 5
MAP2K1 mitogen-activated protein kinase kinase 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MET MET proto-oncogene, receptor tyrosine kinase
MIR146A microRNA 146a
MIR149 microRNA 149
MIR196A1 microRNA 196a-1
MIR499A microRNA 499a
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
RAB4B RAB4B, member RAS oncogene family
RAD18 RAD18 E3 ubiquitin protein ligase
RFC1 replication factor C (activator 1) 1, 145kDa
RRM1 ribonucleotide reductase M1
SH3GLB1 SH3-domain GRB2-like endophilin B1
SIPA1 signal-induced proliferation-associated 1
STK11 serine/threonine kinase 11
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TP53 tumor protein p53
TYMS thymidylate synthetase
VEGFA vascular endothelial growth factor A
WWOX WW domain containing oxidoreductase
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3