Cancer of thyroid_Thyroid_GSE5364 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE5364
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Genes

600 genes differentially expressed during Cancer of thyroid_Thyroid_GSE5364 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
CCNI cyclin I 3.05195
HSPA8 heat shock 70kDa protein 8 2.71832
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 2.68007
UBXN2A UBX domain protein 2A 2.66194
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.63058
UBE2L3 ubiquitin-conjugating enzyme E2L 3 2.57324
CHMP3 charged multivesicular body protein 3 2.53109
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 2.50585
TAGLN2 transgelin 2 2.48711
RRAGC Ras-related GTP binding C 2.48554
CIZ1 CDKN1A interacting zinc finger protein 1 2.48213
RPS11 ribosomal protein S11 2.46808
EIF3K eukaryotic translation initiation factor 3, subunit K 2.44728
RPS5 ribosomal protein S5 2.42898
SEC11A SEC11 homolog A (S. cerevisiae) 2.39725
SNRPA small nuclear ribonucleoprotein polypeptide A 2.3934
SCNM1 sodium channel modifier 1 2.30989
CAPNS1 calpain, small subunit 1 2.30751
SEPT2 septin 2 2.28041
GSTP1 glutathione S-transferase pi 1 2.26231
EIF3E eukaryotic translation initiation factor 3, subunit E 2.25027
S100A11 S100 calcium binding protein A11 2.22341
HFE hemochromatosis 2.18521
RPS3 ribosomal protein S3 2.18263
RPL10A ribosomal protein L10a 2.1764
DYNLRB1 dynein, light chain, roadblock-type 1 2.16818
RPS16 ribosomal protein S16 2.16519
CHD3 chromodomain helicase DNA binding protein 3 2.15515
RHOA ras homolog family member A 2.14923
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) 2.0885
TMED3 transmembrane emp24 protein transport domain containing 3 2.08634
IQGAP1 IQ motif containing GTPase activating protein 1 2.04886
RPS27 ribosomal protein S27 2.02826
EIF3H eukaryotic translation initiation factor 3, subunit H 2.01308
MRPL49 mitochondrial ribosomal protein L49 2.00296
RPS9 ribosomal protein S9 2.00177
PPT1 palmitoyl-protein thioesterase 1 1.9938
RPS2 ribosomal protein S2 1.99118
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.98947
GORASP2 golgi reassembly stacking protein 2, 55kDa 1.98507
CLSTN1 calsyntenin 1 1.96401
BABAM1 BRISC and BRCA1 A complex member 1 1.95721
RPL8 ribosomal protein L8 1.95474
LDHB lactate dehydrogenase B 1.94869
MRPL11 mitochondrial ribosomal protein L11 1.94476
RNF216 ring finger protein 216 1.92332
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa 1.92313
DSTN destrin (actin depolymerizing factor) 1.92258
SNX17 sorting nexin 17 1.92194
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 1.91646
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2 1.90719
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 1.88704
HMGXB3 HMG box domain containing 3 1.8868
H2AFY H2A histone family, member Y 1.8825
PRRC2A proline-rich coiled-coil 2A 1.87534
CLIC1 chloride intracellular channel 1 1.86843
ALDOA aldolase A, fructose-bisphosphate 1.86497
UFD1L ubiquitin fusion degradation 1 like (yeast) 1.85573
BLVRA biliverdin reductase A 1.84229
PCBP1 poly(rC) binding protein 1 1.83308
FOXJ2 forkhead box J2 1.82813
TUBA1B tubulin, alpha 1b 1.82462
KIF5B kinesin family member 5B 1.82065
UBL5 ubiquitin-like 5 1.81378
LGALS3 lectin, galactoside-binding, soluble, 3 1.81351
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 1.81327
ENO1 enolase 1, (alpha) 1.80173
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 1.79987
MAX MYC associated factor X 1.79814
RPA2 replication protein A2, 32kDa 1.78268
RPL36 ribosomal protein L36 1.78012
LPAR2 lysophosphatidic acid receptor 2 1.77766
SF3A1 splicing factor 3a, subunit 1, 120kDa 1.77668
ARF3 ADP-ribosylation factor 3 1.77229
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 1.75967
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 1.75335
RPS8 ribosomal protein S8 1.7514
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 1.74986
ZSWIM4 zinc finger, SWIM-type containing 4 1.74695
LARP1 La ribonucleoprotein domain family, member 1 1.7338
BRD4 bromodomain containing 4 1.7326
MFSD5 major facilitator superfamily domain containing 5 1.73149
LARP4B La ribonucleoprotein domain family, member 4B 1.72929
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) 1.72427
UBE2E1 ubiquitin-conjugating enzyme E2E 1 1.72391
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 1.71919
MED12 mediator complex subunit 12 1.71899
HMGN1 high mobility group nucleosome binding domain 1 1.71899
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) 1.71733
RPS15 ribosomal protein S15 1.71266
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 1.70504
RPL13A ribosomal protein L13a 1.70362
RBMX RNA binding motif protein, X-linked 1.70086
DCAF15 DDB1 and CUL4 associated factor 15 1.69279
UXS1 UDP-glucuronate decarboxylase 1 1.68935
MPZL1 myelin protein zero-like 1 1.68205
ETF1 eukaryotic translation termination factor 1 1.67986
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 1.67709
MOSPD2 motile sperm domain containing 2 1.67343
CNOT8 CCR4-NOT transcription complex, subunit 8 1.67026
MCRS1 microspherule protein 1 1.66033
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 1.65611
CLN3 ceroid-lipofuscinosis, neuronal 3 1.65599
PPP1R7 protein phosphatase 1, regulatory subunit 7 1.65268
NBAS neuroblastoma amplified sequence 1.64897
BARD1 BRCA1 associated RING domain 1 1.64854
TMC6 transmembrane channel-like 6 1.64612
ANXA2 annexin A2 1.64143
DAZAP2 DAZ associated protein 2 1.63345
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 1.63344
RPS3A ribosomal protein S3A 1.6327
RPL28 ribosomal protein L28 1.62705
RAB5B RAB5B, member RAS oncogene family 1.62301
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 1.6189
HMGN4 high mobility group nucleosomal binding domain 4 1.61847
RIC8A RIC8 guanine nucleotide exchange factor A 1.61826
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 1.61784
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) 1.61665
PFDN5 prefoldin subunit 5 1.61115
SLC35E1 solute carrier family 35, member E1 1.60879
RBMS1 RNA binding motif, single stranded interacting protein 1 1.6083
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.6047
SRP72 signal recognition particle 72kDa 1.60128
MCTS1 malignant T cell amplified sequence 1 1.59873
COPS8 COP9 signalosome subunit 8 1.59862
AIP aryl hydrocarbon receptor interacting protein 1.59858
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 1.59125
TMSB10 thymosin beta 10 1.58939
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 1.58926
H3F3B H3 histone, family 3B (H3.3B) 1.57977
NSF N-ethylmaleimide-sensitive factor 1.57786
FAM96B family with sequence similarity 96, member B 1.5777
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 1.57075
CCT4 chaperonin containing TCP1, subunit 4 (delta) 1.56771
TLK2 tousled-like kinase 2 1.56289
GNAS GNAS complex locus 1.56241
C2CD3 C2 calcium-dependent domain containing 3 1.5617
PRMT5 protein arginine methyltransferase 5 1.55059
RBX1 ring-box 1, E3 ubiquitin protein ligase 1.54793
MRPS7 mitochondrial ribosomal protein S7 1.54503
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.54481
ILF2 interleukin enhancer binding factor 2 1.54472
WAC WW domain containing adaptor with coiled-coil 1.54443
RHOC ras homolog family member C 1.53852
MAEA macrophage erythroblast attacher 1.53425
OSTM1 osteopetrosis associated transmembrane protein 1 1.53231
LAMC1 laminin, gamma 1 (formerly LAMB2) 1.53057
FLNA filamin A, alpha 1.52965
SNX27 sorting nexin family member 27 1.52766
ZNF7 zinc finger protein 7 1.52534
NGRN neugrin, neurite outgrowth associated 1.52343
NPC2 Niemann-Pick disease, type C2 1.52036
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 1.51911
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa 1.51488
NME2 NME/NM23 nucleoside diphosphate kinase 2 1.51251
MFAP1 microfibrillar-associated protein 1 1.5115
RPL4 ribosomal protein L4 1.50948
CREB3L2 cAMP responsive element binding protein 3-like 2 1.5058
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 1.50345
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 1.4992
UBE2A ubiquitin-conjugating enzyme E2A 1.49642
AKAP8L A kinase (PRKA) anchor protein 8-like 1.4962
DCLRE1C DNA cross-link repair 1C 1.49618
KATNA1 katanin p60 (ATPase containing) subunit A 1 1.49461
FKBP1A FK506 binding protein 1A, 12kDa 1.4924
MPV17 MpV17 mitochondrial inner membrane protein 1.49064
RPL35 ribosomal protein L35 1.48199
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 1.47823
SMYD3 SET and MYND domain containing 3 1.47139
SWAP70 SWAP switching B-cell complex 70kDa subunit 1.46931
MAPK13 mitogen-activated protein kinase 13 1.46806
SUMO3 small ubiquitin-like modifier 3 1.4635
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 1.46302
ARL5A ADP-ribosylation factor-like 5A 1.4579
TMEM126B transmembrane protein 126B 1.45716
TUBA1C tubulin, alpha 1c 1.45652
TES testin LIM domain protein 1.45053
AES amino-terminal enhancer of split 1.44703
RPL6 ribosomal protein L6 1.44591
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 1.4446
CNOT1 CCR4-NOT transcription complex, subunit 1 1.44277
C14ORF166 chromosome 14 open reading frame 166 1.44096
UBXN1 UBX domain protein 1 1.43975
PHTF1 putative homeodomain transcription factor 1 1.43859
RPS15A ribosomal protein S15a 1.43448
RPL36A ribosomal protein L36a 1.43409
RPLP1 ribosomal protein, large, P1 1.43269
C6ORF48 chromosome 6 open reading frame 48 1.42647
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 1.42482
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 1.42345
DAD1 defender against cell death 1 1.42268
TSPO translocator protein (18kDa) 1.42163
CLTA clathrin, light chain A 1.41857
MYOF myoferlin 1.41808
PLD3 phospholipase D family, member 3 1.41807
NEK7 NIMA-related kinase 7 1.41596
PIGF phosphatidylinositol glycan anchor biosynthesis, class F 1.41529
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 1.40977
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 1.40858
SGSM3 small G protein signaling modulator 3 1.40749
FLII flightless I homolog (Drosophila) 1.40651
IFT57 intraflagellar transport 57 1.40456
ACTB actin, beta 1.40372
FUS FUS RNA binding protein 1.40219
TCTN3 tectonic family member 3 1.39921
GUK1 guanylate kinase 1 1.3954
ELOVL1 ELOVL fatty acid elongase 1 1.39528
EIF3D eukaryotic translation initiation factor 3, subunit D 1.39512
TMEM87A transmembrane protein 87A 1.39431
RPL22L1 ribosomal protein L22-like 1 1.39206
TXNDC9 thioredoxin domain containing 9 1.39079
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 1.38688
MTCH1 mitochondrial carrier 1 1.38666
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 1.38539
RPL3 ribosomal protein L3 1.38099
MOB1A MOB kinase activator 1A 1.37792
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 1.37391
RPL36AP52 ribosomal protein L36a pseudogene 1.37355
TMEM60 transmembrane protein 60 1.37102
RPL18 ribosomal protein L18 1.37036
TOMM34 translocase of outer mitochondrial membrane 34 1.37027
FAM49A family with sequence similarity 49, member A 1.36887
IFT52 intraflagellar transport 52 1.36829
KIF1BP KIF1 binding protein 1.36793
C11ORF49 chromosome 11 open reading frame 49 1.36624
DCP1A decapping mRNA 1A 1.36361
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 1.36325
WWC3 WWC family member 3 1.36194
CRTC3 CREB regulated transcription coactivator 3 1.3615
ATP13A1 ATPase type 13A1 1.36047
AMZ2 archaelysin family metallopeptidase 2 1.35989
CABIN1 calcineurin binding protein 1 1.35909
ADD1 adducin 1 (alpha) 1.35664
RPS17 ribosomal protein S17 1.35573
RALBP1 ralA binding protein 1 1.35441
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 1.35215
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 1.35204
RHOQ ras homolog family member Q 1.34088
CD44 CD44 molecule (Indian blood group) 1.34053
NECAP1 NECAP endocytosis associated 1 1.33843
CHMP1B charged multivesicular body protein 1B 1.33734
EIF3L eukaryotic translation initiation factor 3, subunit L 1.33577
PACS2 phosphofurin acidic cluster sorting protein 2 1.33406
PRKCSH protein kinase C substrate 80K-H 1.3329
CDCP1 CUB domain containing protein 1 1.3305
RPL17 ribosomal protein L17 1.3302
CDR2L cerebellar degeneration-related protein 2-like 1.32981
TEX261 testis expressed 261 1.32268
AAGAB alpha- and gamma-adaptin binding protein 1.32208
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 1.32138
C12ORF49 chromosome 12 open reading frame 49 1.31453
TRIM28 tripartite motif containing 28 1.31248
MORF4L1 mortality factor 4 like 1 1.31205
TSG101 tumor susceptibility 101 1.30975
LIMS1 LIM and senescent cell antigen-like domains 1 1.30901
CAPN2 calpain 2, (m/II) large subunit 1.30818
SH3GLB1 SH3-domain GRB2-like endophilin B1 1.30701
ARF1 ADP-ribosylation factor 1 1.30682
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 1.30629
MAPK1 mitogen-activated protein kinase 1 1.30559
MBD2 methyl-CpG binding domain protein 2 1.30558
RPL7A ribosomal protein L7a 1.30523
SPINT1 serine peptidase inhibitor, Kunitz type 1 1.30409
SMG5 SMG5 nonsense mediated mRNA decay factor 1.30228
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 1.30137
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 1.29743
RCN2 reticulocalbin 2, EF-hand calcium binding domain 1.29666
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.29541
PEA15 phosphoprotein enriched in astrocytes 15 1.29373
MBTPS1 membrane-bound transcription factor peptidase, site 1 1.29309
UBTF upstream binding transcription factor, RNA polymerase I 1.29291
PIH1D1 PIH1 domain containing 1 1.29267
E2F4 E2F transcription factor 4, p107/p130-binding 1.28746
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 1.2864
USP11 ubiquitin specific peptidase 11 1.2847
ADGRL1 adhesion G protein-coupled receptor L1 1.28053
RPL30 ribosomal protein L30 1.28003
HNRNPK heterogeneous nuclear ribonucleoprotein K 1.27973
SF3B3 splicing factor 3b, subunit 3, 130kDa 1.27897
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.27859
ITGB1BP1 integrin beta 1 binding protein 1 1.27817
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 1.27784
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 1.27667
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 1.27323
S100A13 S100 calcium binding protein A13 1.27293
CD63 CD63 molecule 1.27246
SET SET nuclear proto-oncogene 1.27069
GRB7 growth factor receptor-bound protein 7 1.27057
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) 1.26978
CHD8 chromodomain helicase DNA binding protein 8 1.26756
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 1.26727
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 1.26641
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 1.2664
WIPF2 WAS/WASL interacting protein family, member 2 1.26526
ATG7 autophagy related 7 1.26262
ILF3 interleukin enhancer binding factor 3, 90kDa 1.26167
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 1.2606
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 1.2594
COPS7A COP9 signalosome subunit 7A 1.25826
TRIP10 thyroid hormone receptor interactor 10 1.2564

decreased expression

Symbol Name Standardized Value
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -3.86972
C6 complement component 6 -3.76547
HGFAC HGF activator -3.75211
AMBP alpha-1-microglobulin/bikunin precursor -3.7361
SAA4 serum amyloid A4, constitutive -3.68141
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 -3.64679
APOB apolipoprotein B -3.46539
APOC3 apolipoprotein C-III -3.46355
ALDOB aldolase B, fructose-bisphosphate -3.36829
KNG1 kininogen 1 -3.35347
LECT2 leukocyte cell-derived chemotaxin 2 -3.25234
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -3.23434
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -3.21617
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -3.01191
ETFDH electron-transferring-flavoprotein dehydrogenase -2.99682
HRG histidine-rich glycoprotein -2.94523
LBP lipopolysaccharide binding protein -2.94325
APOM apolipoprotein M -2.89552
ACF Asymmetric crying facies (Cayler cardiofacial syndrome) -2.88601
C8G complement component 8, gamma polypeptide -2.87523
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 -2.82398
C8A complement component 8, alpha polypeptide -2.82044
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 -2.79608
HAO1 hydroxyacid oxidase (glycolate oxidase) 1 -2.79363
AGXT alanine-glyoxylate aminotransferase -2.78465
CLEC4M C-type lectin domain family 4, member M -2.77305
CES2 carboxylesterase 2 -2.75542
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 -2.75074
APOA1 apolipoprotein A-I -2.746
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase -2.72174
MAT1A methionine adenosyltransferase I, alpha -2.69108
G2E3 G2/M-phase specific E3 ubiquitin protein ligase -2.67264
APOC4 apolipoprotein C-IV -2.67183
CFHR5 complement factor H-related 5 -2.66269
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide -2.6614
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 -2.66056
APOA2 apolipoprotein A-II -2.62756
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 -2.6075
CFHR2 complement factor H-related 2 -2.59707
TPMT thiopurine S-methyltransferase -2.58946
F2 coagulation factor II (thrombin) -2.576
APCS amyloid P component, serum -2.55459
FTL ferritin, light polypeptide -2.54857
LYRM1 LYR motif containing 1 -2.54346
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 -2.54273
PEBP1 phosphatidylethanolamine binding protein 1 -2.5414
ALB albumin -2.53159
AFM afamin -2.52852
TCAF1 TRPM8 channel-associated factor 1 -2.5248
ASGR2 asialoglycoprotein receptor 2 -2.50828
PIPOX pipecolic acid oxidase -2.49206
HRSP12 heat-responsive protein 12 -2.47995
AKR1D1 aldo-keto reductase family 1, member D1 -2.46281
OXSM 3-oxoacyl-ACP synthase, mitochondrial -2.44409
MPC1 mitochondrial pyruvate carrier 1 -2.44233
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -2.41284
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 -2.40342
FABP1 fatty acid binding protein 1, liver -2.39921
GLYAT glycine-N-acyltransferase -2.39796
SLC38A3 solute carrier family 38, member 3 -2.3838
NR1I3 nuclear receptor subfamily 1, group I, member 3 -2.38109
ACAA1 acetyl-CoA acyltransferase 1 -2.3547
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 -2.35116
HPD 4-hydroxyphenylpyruvate dioxygenase -2.34332
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -2.34021
RPL39 ribosomal protein L39 -2.31296
HAO2 hydroxyacid oxidase 2 (long chain) -2.30946
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 -2.30461
PNPLA3 patatin-like phospholipase domain containing 3 -2.28443
SOD1 superoxide dismutase 1, soluble -2.28209
STAU1 staufen double-stranded RNA binding protein 1 -2.27803
TPT1 tumor protein, translationally-controlled 1 -2.27727
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 -2.27315
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 -2.27154
SPP2 secreted phosphoprotein 2, 24kDa -2.26528
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial -2.26227
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 -2.24892
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) -2.23711
PAPD7 PAP associated domain containing 7 -2.20353
MUT methylmalonyl CoA mutase -2.20207
PLGLB2 plasminogen-like B2 -2.19654
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 -2.19234
HPX hemopexin -2.1751
ACSL1 acyl-CoA synthetase long-chain family member 1 -2.1473
HAGH hydroxyacylglutathione hydrolase -2.14338
PHYH phytanoyl-CoA 2-hydroxylase -2.13939
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -2.1298
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 -2.12077
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 -2.11862
FBXO7 F-box protein 7 -2.11699
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 -2.11404
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) -2.10897
GAPT GRB2-binding adaptor protein, transmembrane -2.1088
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -2.09859
SCAP SREBF chaperone -2.09658
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 -2.08977
MRPS31 mitochondrial ribosomal protein S31 -2.06245
BHMT betaine--homocysteine S-methyltransferase -2.06187
SCP2 sterol carrier protein 2 -2.02725
TAT tyrosine aminotransferase -2.02367
CDO1 cysteine dioxygenase type 1 -2.0103
HGD homogentisate 1,2-dioxygenase -2.00776
LCAT lecithin-cholesterol acyltransferase -2.00724
RAP2C RAP2C, member of RAS oncogene family -2.00338
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7 -1.99548
ARG1 arginase 1 -1.99465
TDO2 tryptophan 2,3-dioxygenase -1.99229
HADH hydroxyacyl-CoA dehydrogenase -1.98564
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -1.98414
COLEC11 collectin sub-family member 11 -1.97386
PRODH2 proline dehydrogenase (oxidase) 2 -1.97142
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 -1.93639
PROC protein C (inactivator of coagulation factors Va and VIIIa) -1.93491
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -1.9204
PON1 paraoxonase 1 -1.91006
F11 coagulation factor XI -1.90781
TTC38 tetratricopeptide repeat domain 38 -1.8934
OTC ornithine carbamoyltransferase -1.892
PPP6R2 protein phosphatase 6, regulatory subunit 2 -1.87622
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -1.8733
SEPHS2 selenophosphate synthetase 2 -1.8671
AHSG alpha-2-HS-glycoprotein -1.85934
F7 coagulation factor VII (serum prothrombin conversion accelerator) -1.85905
HAL histidine ammonia-lyase -1.8583
MT1F metallothionein 1F -1.85456
PLG plasminogen -1.85317
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -1.84653
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -1.83163
ZG16 zymogen granule protein 16 -1.82633
ACSM2B acyl-CoA synthetase medium-chain family member 2B -1.82426
ISOC1 isochorismatase domain containing 1 -1.82262
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 -1.81926
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -1.81138
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -1.81116
C8B complement component 8, beta polypeptide -1.80866
PDIA4 protein disulfide isomerase family A, member 4 -1.80812
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain -1.80446
PBLD phenazine biosynthesis-like protein domain containing -1.7978
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 -1.79738
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit -1.79115
MPST mercaptopyruvate sulfurtransferase -1.78103
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 -1.77913
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -1.7742
PDZK1 PDZ domain containing 1 -1.77207
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 -1.76694
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -1.76513
WWP1 WW domain containing E3 ubiquitin protein ligase 1 -1.74895
CACFD1 calcium channel flower domain containing 1 -1.74674
STEAP3 STEAP family member 3, metalloreductase -1.74567
KHK ketohexokinase (fructokinase) -1.7438
PDE12 phosphodiesterase 12 -1.74284
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) -1.74226
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 -1.72431
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 -1.72424
GALT galactose-1-phosphate uridylyltransferase -1.72218
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 -1.72149
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 -1.70745
GLUD2 glutamate dehydrogenase 2 -1.70522
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 -1.70353
DESI2 desumoylating isopeptidase 2 -1.70272
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 -1.7007
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9 -1.6977
MIA3 melanoma inhibitory activity family, member 3 -1.69749
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 -1.6855
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 -1.68515
ZNF235 zinc finger protein 235 -1.67817
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 -1.66815
POLR1C polymerase (RNA) I polypeptide C, 30kDa -1.6621
ACADVL acyl-CoA dehydrogenase, very long chain -1.65045
CTAGE5 CTAGE family, member 5 -1.64594
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like -1.64042
TF transferrin -1.63978
CFB complement factor B -1.63772
ABHD10 abhydrolase domain containing 10 -1.6368
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I -1.63332
AR androgen receptor -1.6305
CBR4 carbonyl reductase 4 -1.62881
AKAP11 A kinase (PRKA) anchor protein 11 -1.62597
AKAP7 A kinase (PRKA) anchor protein 7 -1.6116
DAO D-amino-acid oxidase -1.60796
CBS cystathionine-beta-synthase -1.60304
ALDH1B1 aldehyde dehydrogenase 1 family, member B1 -1.59669
COL18A1 collagen, type XVIII, alpha 1 -1.59423
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) -1.59144
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) -1.58955
SAR1B secretion associated, Ras related GTPase 1B -1.58876
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 -1.58721
ALAS1 5'-aminolevulinate synthase 1 -1.57583
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -1.57008
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 -1.56918
DHRS1 dehydrogenase/reductase (SDR family) member 1 -1.56767
TRPV1 transient receptor potential cation channel, subfamily V, member 1 -1.56688
C9 complement component 9 -1.56601
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial -1.564
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 -1.56345
ZNF778 zinc finger protein 778 -1.56108
CIDEB cell death-inducing DFFA-like effector b -1.55011
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 -1.54918
TTR transthyretin -1.5486
PKLR pyruvate kinase, liver and RBC -1.54798
ARHGAP1 Rho GTPase activating protein 1 -1.54689
LIPC lipase, hepatic -1.54609
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 -1.53774
DHODH dihydroorotate dehydrogenase (quinone) -1.53766
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -1.53691
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) -1.5367
GYG2 glycogenin 2 -1.53637
MGST2 microsomal glutathione S-transferase 2 -1.53461
ACAT1 acetyl-CoA acetyltransferase 1 -1.52846
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 -1.52817
FAM8A1 family with sequence similarity 8, member A1 -1.52598
CDC37L1 cell division cycle 37-like 1 -1.52106
MSRA methionine sulfoxide reductase A -1.51343
PTH1R parathyroid hormone 1 receptor -1.50622
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -1.49344
PQLC1 PQ loop repeat containing 1 -1.49274
SEC24A SEC24 family member A -1.49186
SCML1 sex comb on midleg-like 1 (Drosophila) -1.49056
ZCCHC6 zinc finger, CCHC domain containing 6 -1.49032
C21ORF33 chromosome 21 open reading frame 33 -1.48676
APMAP adipocyte plasma membrane associated protein -1.485
FXN frataxin -1.47933
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 -1.47803
LRRC40 leucine rich repeat containing 40 -1.47467
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -1.47367
N4BP2L1 NEDD4 binding protein 2-like 1 -1.46339
UBB ubiquitin B -1.4626
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -1.45961
ADI1 acireductone dioxygenase 1 -1.45519
PROZ protein Z, vitamin K-dependent plasma glycoprotein -1.45278
BAAT bile acid CoA:amino acid N-acyltransferase -1.45062
FGL1 fibrinogen-like 1 -1.4488
PECR peroxisomal trans-2-enoyl-CoA reductase -1.44842
TFR2 transferrin receptor 2 -1.44818
SLC25A44 solute carrier family 25, member 44 -1.44065
KCNQ1DN KCNQ1 downstream neighbor (non-protein coding) -1.43757
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -1.43448
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -1.42901
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -1.42589
B2M beta-2-microglobulin -1.42056
MYO7B myosin VIIB -1.4204
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -1.41487
GLT8D1 glycosyltransferase 8 domain containing 1 -1.41379
ASS1 argininosuccinate synthase 1 -1.41342
TLX2 T-cell leukemia homeobox 2 -1.40975
MTMR4 myotubularin related protein 4 -1.4085
ADGRA3 adhesion G protein-coupled receptor A3 -1.40664
R3HDM2 R3H domain containing 2 -1.40608
RCL1 RNA terminal phosphate cyclase-like 1 -1.40209
CMC4 C-x(9)-C motif containing 4 -1.40124
ZC3H14 zinc finger CCCH-type containing 14 -1.40114
WDR35 WD repeat domain 35 -1.39765
NCOA4 nuclear receptor coactivator 4 -1.39558
POR P450 (cytochrome) oxidoreductase -1.39038
GCKR glucokinase (hexokinase 4) regulator -1.39036
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) -1.38732
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 -1.38537
ALAD aminolevulinate dehydratase -1.38534
CSAD cysteine sulfinic acid decarboxylase -1.38517
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa -1.38371
RPL37A ribosomal protein L37a -1.38286
CES3 carboxylesterase 3 -1.38178
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 -1.37721
F12 coagulation factor XII (Hageman factor) -1.37701
WWOX WW domain containing oxidoreductase -1.37331
TRIAP1 TP53 regulated inhibitor of apoptosis 1 -1.37059
NR1H4 nuclear receptor subfamily 1, group H, member 4 -1.37044
CD5L CD5 molecule-like -1.36807
TTC31 tetratricopeptide repeat domain 31 -1.36671
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 -1.36551
CETP cholesteryl ester transfer protein, plasma -1.36177
F9 coagulation factor IX -1.36011
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -1.3601
ADH6 alcohol dehydrogenase 6 (class V) -1.35929
NRL neural retina leucine zipper -1.35807
VWA8 von Willebrand factor A domain containing 8 -1.35796
RBM6 RNA binding motif protein 6 -1.35641
GCDH glutaryl-CoA dehydrogenase -1.35483
GCAT glycine C-acetyltransferase -1.35361
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -1.35189
MTTP microsomal triglyceride transfer protein -1.34749
EIF4E1B eukaryotic translation initiation factor 4E family member 1B -1.34588
CRP C-reactive protein, pentraxin-related -1.34524
GNMT glycine N-methyltransferase -1.3437
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) -1.34322
CHPT1 choline phosphotransferase 1 -1.33855
CCDC25 coiled-coil domain containing 25 -1.33691
GOT1 glutamic-oxaloacetic transaminase 1, soluble -1.33592
PANK3 pantothenate kinase 3 -1.33352
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -1.32935
NBPF14 neuroblastoma breakpoint family, member 14 -1.32876
IGFBP1 insulin-like growth factor binding protein 1 -1.32815
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) -1.32696
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -1.32643
MAN2A2 mannosidase, alpha, class 2A, member 2 -1.32633
INSIG1 insulin induced gene 1 -1.32434
ECHDC2 enoyl CoA hydratase domain containing 2 -1.32363
GLUD1 glutamate dehydrogenase 1 -1.3236
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -1.32317
TSSK1B testis-specific serine kinase 1B -1.32133