CXCR4-mediated signaling events Gene Set

Dataset PID Pathways
Category structural or functional annotations
Type pathway
External Link http://public.ndexbio.org/#/network/46a5529b-6191-11e5-8ac5-06603eb7f303
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Genes

100 proteins participating in the CXCR4-mediated signaling events pathway from the PID Pathways dataset.

Symbol Name
ADRBK1 adrenergic, beta, receptor kinase 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ARR3 arrestin 3, retinal (X-arrestin)
ARRB2 arrestin, beta 2
BAD BCL2-associated agonist of cell death
BCAR1 breast cancer anti-estrogen resistance 1
BLK BLK proto-oncogene, Src family tyrosine kinase
CD247 CD247 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD4 CD4 molecule
CDC42 cell division cycle 42
CFL1 cofilin 1 (non-muscle)
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSK c-src tyrosine kinase
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
DNM1 dynamin 1
FGR FGR proto-oncogene, Src family tyrosine kinase
FOXO1 forkhead box O1
FYN FYN proto-oncogene, Src family tyrosine kinase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GRK6 G protein-coupled receptor kinase 6
HCK HCK proto-oncogene, Src family tyrosine kinase
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HLA-DRA major histocompatibility complex, class II, DR alpha
ITCH itchy E3 ubiquitin protein ligase
ITGA1 integrin, alpha 1
ITGA10 integrin, alpha 10
ITGA11 integrin, alpha 11
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGA6 integrin, alpha 6
ITGA7 integrin, alpha 7
ITGA8 integrin, alpha 8
ITGA9 integrin, alpha 9
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JAK2 Janus kinase 2
LCK LCK proto-oncogene, Src family tyrosine kinase
LIMK1 LIM domain kinase 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MAPKAP1 mitogen-activated protein kinase associated protein 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MMP9 matrix metallopeptidase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDPK1 3-phosphoinositide dependent protein kinase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCB2 phospholipase C, beta 2
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PRKCZ protein kinase C, zeta
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PXN paxillin
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RALB v-ral simian leukemia viral oncogene homolog B
RAP1B RAP1B, member of RAS oncogene family
RGS1 regulator of G-protein signaling 1
RHOA ras homolog family member A
RHOB ras homolog family member B
RHOC ras homolog family member C
RICTOR RPTOR independent companion of MTOR, complex 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSH1 slingshot protein phosphatase 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
UBQLN1 ubiquilin 1
VAV1 vav 1 guanine nucleotide exchange factor
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
YES1 YES proto-oncogene 1, Src family tyrosine kinase