CP-944629-7549 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the CP-944629-7549 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACSL6 acyl-CoA synthetase long-chain family member 6
ADAM12 ADAM metallopeptidase domain 12
ADGRB2 adhesion G protein-coupled receptor B2
ADGRG2 adhesion G protein-coupled receptor G2
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AGRN agrin
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
CACFD1 calcium channel flower domain containing 1
CASZ1 castor zinc finger 1
CCDC28B coiled-coil domain containing 28B
CCDC7 coiled-coil domain containing 7
CCDC9 coiled-coil domain containing 9
CD82 CD82 molecule
CDK12 cyclin-dependent kinase 12
CEP135 centrosomal protein 135kDa
COPE coatomer protein complex, subunit epsilon
CRY2 cryptochrome circadian clock 2
CTSF cathepsin F
CXCL12 chemokine (C-X-C motif) ligand 12
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DAPK3 death-associated protein kinase 3
DOCK9 dedicator of cytokinesis 9
ELOVL5 ELOVL fatty acid elongase 5
ERAP1 endoplasmic reticulum aminopeptidase 1
EXD3 exonuclease 3'-5' domain containing 3
FKBP10 FK506 binding protein 10, 65 kDa
FLCN folliculin
FLOT2 flotillin 2
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GMPR guanosine monophosphate reductase
HFE hemochromatosis
HLX H2.0-like homeobox
HMHA1 histocompatibility (minor) HA-1
IL11 interleukin 11
ITPKA inositol-trisphosphate 3-kinase A
KDM6B lysine (K)-specific demethylase 6B
KIAA0226 KIAA0226
KLHL25 kelch-like family member 25
LAPTM5 lysosomal protein transmembrane 5
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC647070 uncharacterized LOC647070
LZTR1 leucine-zipper-like transcription regulator 1
MAST4 microtubule associated serine/threonine kinase family member 4
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MINK1 misshapen-like kinase 1
MYH15 myosin, heavy chain 15
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAAA N-acylethanolamine acid amidase
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NYNRIN NYN domain and retroviral integrase containing
OGFR opioid growth factor receptor
PADI1 peptidyl arginine deiminase, type I
PLD2 phospholipase D2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTN pleiotrophin
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPAIN RPA interacting protein
RPH3AL rabphilin 3A-like (without C2 domains)
S100A3 S100 calcium binding protein A3
SAMD9 sterile alpha motif domain containing 9
SCARB2 scavenger receptor class B, member 2
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SIPA1L3 signal-induced proliferation-associated 1 like 3
SIX1 SIX homeobox 1
SKIL SKI-like proto-oncogene
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLN sarcolipin
SMG5 SMG5 nonsense mediated mRNA decay factor
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SNTA1 syntrophin, alpha 1
STC1 stanniocalcin 1
SUGCT succinyl-CoA:glutarate-CoA transferase
SYT11 synaptotagmin XI
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TJP3 tight junction protein 3
TRIM14 tripartite motif containing 14
TRIM3 tripartite motif containing 3
VAC14 Vac14 homolog (S. cerevisiae)
VAV2 vav 2 guanine nucleotide exchange factor
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
XYLB xylulokinase homolog (H. influenzae)
ZBTB39 zinc finger and BTB domain containing 39
ZC3H7B zinc finger CCCH-type containing 7B
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZER1 zyg-11 related, cell cycle regulator
ZNF358 zinc finger protein 358
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AKTIP AKT interacting protein
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGAP12 Rho GTPase activating protein 12
BFSP1 beaded filament structural protein 1, filensin
BMP4 bone morphogenetic protein 4
BPGM 2,3-bisphosphoglycerate mutase
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C17ORF80 chromosome 17 open reading frame 80
C1ORF56 chromosome 1 open reading frame 56
C6ORF47 chromosome 6 open reading frame 47
CBR4 carbonyl reductase 4
CCL22 chemokine (C-C motif) ligand 22
CDC73 cell division cycle 73
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CLDND1 claudin domain containing 1
CLIP4 CAP-GLY domain containing linker protein family, member 4
CLTCL1 clathrin, heavy chain-like 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DBR1 debranching RNA lariats 1
DCAF13 DDB1 and CUL4 associated factor 13
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
EML4 echinoderm microtubule associated protein like 4
EXOC5 exocyst complex component 5
FANCF Fanconi anemia, complementation group F
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FLRT3 fibronectin leucine rich transmembrane protein 3
FZD3 frizzled class receptor 3
GLCE glucuronic acid epimerase
GPR176 G protein-coupled receptor 176
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H3I histone cluster 1, H3i
HSPA2 heat shock 70kDa protein 2
IL6 interleukin 6
IPO8 importin 8
KCNK10 potassium channel, two pore domain subfamily K, member 10
KIAA0895 KIAA0895
KLHL12 kelch-like family member 12
LAX1 lymphocyte transmembrane adaptor 1
LMAN1 lectin, mannose-binding, 1
LMO7 LIM domain 7
LOC100294391 uncharacterized LOC100294391
LPAR3 lysophosphatidic acid receptor 3
LRRC61 leucine rich repeat containing 61
LRRK1 leucine-rich repeat kinase 1
MAGEF1 melanoma antigen family F1
MANEA mannosidase, endo-alpha
MBTPS2 membrane-bound transcription factor peptidase, site 2
MOCS3 molybdenum cofactor synthesis 3
MORC3 MORC family CW-type zinc finger 3
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEK11 NIMA-related kinase 11
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NID2 nidogen 2 (osteonidogen)
NMD3 NMD3 ribosome export adaptor
NNT nicotinamide nucleotide transhydrogenase
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OSMR oncostatin M receptor
PARPBP PARP1 binding protein
PAX9 paired box 9
PCOLCE procollagen C-endopeptidase enhancer
PDE12 phosphodiesterase 12
PGPEP1 pyroglutamyl-peptidase I
PHF14 PHD finger protein 14
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PLEKHA6 pleckstrin homology domain containing, family A member 6
PODXL2 podocalyxin-like 2
PSAT1 phosphoserine aminotransferase 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RGS17 regulator of G-protein signaling 17
RNF146 ring finger protein 146
RPL13P5 ribosomal protein L13 pseudogene 5
RSL24D1 ribosomal L24 domain containing 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RUNDC3B RUN domain containing 3B
SCML1 sex comb on midleg-like 1 (Drosophila)
SGPP1 sphingosine-1-phosphate phosphatase 1
TESK2 testis-specific kinase 2
TMEM230 transmembrane protein 230
TRIM45 tripartite motif containing 45
TSPAN1 tetraspanin 1
TTLL7 tubulin tyrosine ligase-like family member 7
TUBA3D tubulin, alpha 3d
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZFP30 ZFP30 zinc finger protein
ZNF137P zinc finger protein 137, pseudogene
ZNF254 zinc finger protein 254
ZNF37BP zinc finger protein 37B, pseudogene
ZNF480 zinc finger protein 480
ZNF510 zinc finger protein 510
ZNF552 zinc finger protein 552
ZNF675 zinc finger protein 675
ZNF711 zinc finger protein 711