CP-944629-7544 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the CP-944629-7544 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ADAP1 ArfGAP with dual PH domains 1
ADRBK1 adrenergic, beta, receptor kinase 1
AFF2 AF4/FMR2 family, member 2
AOX1 aldehyde oxidase 1
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
APOL2 apolipoprotein L, 2
AQP3 aquaporin 3 (Gill blood group)
ASIC1 acid sensing (proton gated) ion channel 1
B9D1 B9 protein domain 1
BBS7 Bardet-Biedl syndrome 7
BLVRA biliverdin reductase A
C1ORF61 chromosome 1 open reading frame 61
C2ORF54 chromosome 2 open reading frame 54
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CCDC28B coiled-coil domain containing 28B
CDK20 cyclin-dependent kinase 20
CDK3 cyclin-dependent kinase 3
CNOT4 CCR4-NOT transcription complex, subunit 4
COL1A1 collagen, type I, alpha 1
COL5A1 collagen, type V, alpha 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DOK4 docking protein 4
DTNA dystrobrevin, alpha
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EGFL7 EGF-like-domain, multiple 7
ELL2 elongation factor, RNA polymerase II, 2
EMC1 ER membrane protein complex subunit 1
EXOC7 exocyst complex component 7
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FH fumarate hydratase
FLT4 fms-related tyrosine kinase 4
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GPR153 G protein-coupled receptor 153
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
HDAC7 histone deacetylase 7
HN1L hematological and neurological expressed 1-like
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL15RA interleukin 15 receptor, alpha
ISG20 interferon stimulated exonuclease gene 20kDa
KDM4C lysine (K)-specific demethylase 4C
KRIT1 KRIT1, ankyrin repeat containing
KRT15 keratin 15, type I
KRT17 keratin 17, type I
LAMP1 lysosomal-associated membrane protein 1
LGALS4 lectin, galactoside-binding, soluble, 4
LMF1 lipase maturation factor 1
LMO4 LIM domain only 4
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MET MET proto-oncogene, receptor tyrosine kinase
MUC3A mucin 3A, cell surface associated
MUC3B mucin 3B, cell surface associated
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NR2E3 nuclear receptor subfamily 2, group E, member 3
OASL 2'-5'-oligoadenylate synthetase-like
PAOX polyamine oxidase (exo-N4-amino)
PAPOLA poly(A) polymerase alpha
PARD6A par-6 family cell polarity regulator alpha
PASK PAS domain containing serine/threonine kinase
PBX2 pre-B-cell leukemia homeobox 2
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PKP2 plakophilin 2
PLAUR plasminogen activator, urokinase receptor
PLK3 polo-like kinase 3
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PPT2 palmitoyl-protein thioesterase 2
PRSS16 protease, serine, 16 (thymus)
PTCD2 pentatricopeptide repeat domain 2
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RARA retinoic acid receptor, alpha
REEP1 receptor accessory protein 1
RHOQ ras homolog family member Q
RTN2 reticulon 2
S100A2 S100 calcium binding protein A2
SDC3 syndecan 3
SGSM3 small G protein signaling modulator 3
SIKE1 suppressor of IKBKE 1
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SPATA5L1 spermatogenesis associated 5-like 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STK24 serine/threonine kinase 24
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TMC5 transmembrane channel-like 5
TRIM2 tripartite motif containing 2
TUBG2 tubulin, gamma 2
TYMS thymidylate synthetase
UBB ubiquitin B
UEVLD UEV and lactate/malate dehyrogenase domains
USP27X ubiquitin specific peptidase 27, X-linked
VASH2 vasohibin 2
WSCD1 WSC domain containing 1
ZDHHC14 zinc finger, DHHC-type containing 14
ZDHHC17 zinc finger, DHHC-type containing 17
ZNF696 zinc finger protein 696
ZNF862 zinc finger protein 862
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AHCTF1 AT hook containing transcription factor 1
AHR aryl hydrocarbon receptor
ALOX15 arachidonate 15-lipoxygenase
ANXA2P3 annexin A2 pseudogene 3
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARMCX2 armadillo repeat containing, X-linked 2
ATF3 activating transcription factor 3
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BATF basic leucine zipper transcription factor, ATF-like
BCL9 B-cell CLL/lymphoma 9
BGLAP bone gamma-carboxyglutamate (gla) protein
C1ORF159 chromosome 1 open reading frame 159
CCDC71 coiled-coil domain containing 71
CCP110 centriolar coiled coil protein 110kDa
CDKL3 cyclin-dependent kinase-like 3
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CHKB choline kinase beta
CHML choroideremia-like (Rab escort protein 2)
CHRM3 cholinergic receptor, muscarinic 3
CLCN5 chloride channel, voltage-sensitive 5
CLSTN2 calsyntenin 2
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
EGLN3 egl-9 family hypoxia-inducible factor 3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELP6 elongator acetyltransferase complex subunit 6
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ETV7 ets variant 7
FAM120C family with sequence similarity 120C
FBXL4 F-box and leucine-rich repeat protein 4
FGD6 FYVE, RhoGEF and PH domain containing 6
FKRP fukutin related protein
FOXI1 forkhead box I1
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HYAL3 hyaluronoglucosaminidase 3
IFI6 interferon, alpha-inducible protein 6
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JADE1 jade family PHD finger 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCTD20 potassium channel tetramerization domain containing 20
KLHL25 kelch-like family member 25
KPTN kaptin (actin binding protein)
KRI1 KRI1 homolog (S. cerevisiae)
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LZTFL1 leucine zipper transcription factor-like 1
MBNL3 muscleblind-like splicing regulator 3
METTL16 methyltransferase like 16
NCS1 neuronal calcium sensor 1
OLFML2A olfactomedin-like 2A
PAX9 paired box 9
PCNXL4 pecanex-like 4 (Drosophila)
PLA2G15 phospholipase A2, group XV
PLAC1 placenta-specific 1
PLCD1 phospholipase C, delta 1
POLL polymerase (DNA directed), lambda
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PSKH1 protein serine kinase H1
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PTTG3P pituitary tumor-transforming 3, pseudogene
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB23 RAB23, member RAS oncogene family
RAB36 RAB36, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RHOBTB2 Rho-related BTB domain containing 2
RPL23AP32 ribosomal protein L23a pseudogene 32
SARS2 seryl-tRNA synthetase 2, mitochondrial
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STAG3 stromal antigen 3
STIM1 stromal interaction molecule 1
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TAOK1 TAO kinase 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFBR3 transforming growth factor, beta receptor III
TICAM1 toll-like receptor adaptor molecule 1
TIGD6 tigger transposable element derived 6
TNNI3 troponin I type 3 (cardiac)
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTBK2 tau tubulin kinase 2
ULBP2 UL16 binding protein 2
UNC119 unc-119 homolog (C. elegans)
USB1 U6 snRNA biogenesis 1
VGF VGF nerve growth factor inducible
VLDLR very low density lipoprotein receptor
WDR60 WD repeat domain 60
WWC2 WW and C2 domain containing 2
ZFP69B ZFP69 zinc finger protein B
ZNF273 zinc finger protein 273
ZNF551 zinc finger protein 551
ZNF767P zinc finger family member 767, pseudogene
ZNF816 zinc finger protein 816