CP-944629-7497 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the CP-944629-7497 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AK2 adenylate kinase 2
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
APLP1 amyloid beta (A4) precursor-like protein 1
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASPHD1 aspartate beta-hydroxylase domain containing 1
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
C14ORF93 chromosome 14 open reading frame 93
C1ORF56 chromosome 1 open reading frame 56
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMK1 calcium/calmodulin-dependent protein kinase I
CASP1 caspase 1, apoptosis-related cysteine peptidase
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDK18 cyclin-dependent kinase 18
CDK19 cyclin-dependent kinase 19
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CEP290 centrosomal protein 290kDa
CHKB choline kinase beta
CLCA1 chloride channel accessory 1
CRTC1 CREB regulated transcription coactivator 1
CUL9 cullin 9
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DALRD3 DALR anticodon binding domain containing 3
DNM2 dynamin 2
EFNB3 ephrin-B3
EMID1 EMI domain containing 1
ESR1 estrogen receptor 1
EXOC7 exocyst complex component 7
FAM50B family with sequence similarity 50, member B
FEM1B fem-1 homolog b (C. elegans)
GBP2 guanylate binding protein 2, interferon-inducible
GMEB1 glucocorticoid modulatory element binding protein 1
GSAP gamma-secretase activating protein
GSTT1 glutathione S-transferase theta 1
HDAC7 histone deacetylase 7
HIST1H2AL histone cluster 1, H2al
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
JUN jun proto-oncogene
KCTD17 potassium channel tetramerization domain containing 17
KCTD7 potassium channel tetramerization domain containing 7
LDAH lipid droplet associated hydrolase
LMO4 LIM domain only 4
LONP2 lon peptidase 2, peroxisomal
LPPR2 lipid phosphate phosphatase-related protein type 2
LRRC61 leucine rich repeat containing 61
LTB4R leukotriene B4 receptor
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MED18 mediator complex subunit 18
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MRPS11 mitochondrial ribosomal protein S11
MTMR2 myotubularin related protein 2
NAIP NLR family, apoptosis inhibitory protein
NECAB2 N-terminal EF-hand calcium binding protein 2
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
OVGP1 oviductal glycoprotein 1, 120kDa
PAIP2B poly(A) binding protein interacting protein 2B
PARD3 par-3 family cell polarity regulator
PDGFA platelet-derived growth factor alpha polypeptide
PHKA2 phosphorylase kinase, alpha 2 (liver)
PLA2G15 phospholipase A2, group XV
POFUT1 protein O-fucosyltransferase 1
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPP1R7 protein phosphatase 1, regulatory subunit 7
PRSS16 protease, serine, 16 (thymus)
PSEN2 presenilin 2
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAB35 RAB35, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RANBP3 RAN binding protein 3
RASAL2 RAS protein activator like 2
RPS28 ribosomal protein S28
SIX1 SIX homeobox 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC25A40 solute carrier family 25, member 40
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMC4 structural maintenance of chromosomes 4
SNW1 SNW domain containing 1
STX3 syntaxin 3
SUN1 Sad1 and UNC84 domain containing 1
SYBU syntabulin (syntaxin-interacting)
TRAK1 trafficking protein, kinesin binding 1
TRIM45 tripartite motif containing 45
TRIO trio Rho guanine nucleotide exchange factor
TTC28 tetratricopeptide repeat domain 28
TTLL3 tubulin tyrosine ligase-like family member 3
U2AF2 U2 small nuclear RNA auxiliary factor 2
URI1 URI1, prefoldin-like chaperone
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WSB1 WD repeat and SOCS box containing 1
ZBTB14 zinc finger and BTB domain containing 14
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF253 zinc finger protein 253
ZNF444 zinc finger protein 444
ZNF609 zinc finger protein 609
ZNF821 zinc finger protein 821
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ARMC6 armadillo repeat containing 6
BGLAP bone gamma-carboxyglutamate (gla) protein
C11ORF21 chromosome 11 open reading frame 21
C21ORF91 chromosome 21 open reading frame 91
C22ORF46 chromosome 22 open reading frame 46
CALML5 calmodulin-like 5
CD1A CD1a molecule
CD8A CD8a molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
CRYBG3 beta-gamma crystallin domain containing 3
CTAGE9 CTAGE family, member 9
CYB5R2 cytochrome b5 reductase 2
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELP6 elongator acetyltransferase complex subunit 6
FAM212B family with sequence similarity 212, member B
FBXO46 F-box protein 46
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FFAR2 free fatty acid receptor 2
FLNC filamin C, gamma
FRMD1 FERM domain containing 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GDAP1 ganglioside induced differentiation associated protein 1
GFI1 growth factor independent 1 transcription repressor
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GSTCD glutathione S-transferase, C-terminal domain containing
HCRTR2 hypocretin (orexin) receptor 2
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2AJ histone cluster 1, H2aj
HPN hepsin
IL36RN interleukin 36 receptor antagonist
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KATNBL1 katanin p80 subunit B-like 1
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KIF5A kinesin family member 5A
KLHL25 kelch-like family member 25
KRT83 keratin 83, type II
LGALS2 lectin, galactoside-binding, soluble, 2
LINC00260 long intergenic non-protein coding RNA 260
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAL mal, T-cell differentiation protein
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MBIP MAP3K12 binding inhibitory protein 1
MORN1 MORN repeat containing 1
MST1R macrophage stimulating 1 receptor
MUC3A mucin 3A, cell surface associated
MYO1F myosin IF
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OTUD3 OTU deubiquitinase 3
PCDHGB5 protocadherin gamma subfamily B, 5
PHOX2A paired-like homeobox 2a
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PRDM14 PR domain containing 14
PRDM5 PR domain containing 5
PROCR protein C receptor, endothelial
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RNF122 ring finger protein 122
RNF170 ring finger protein 170
RPL23AP32 ribosomal protein L23a pseudogene 32
SHARPIN SHANK-associated RH domain interactor
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC30A4 solute carrier family 30 (zinc transporter), member 4
SLC35F5 solute carrier family 35, member F5
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLPI secretory leukocyte peptidase inhibitor
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNTA1 syntrophin, alpha 1
SNX29 sorting nexin 29
SPAG4 sperm associated antigen 4
SPINK1 serine peptidase inhibitor, Kazal type 1
SPINK5 serine peptidase inhibitor, Kazal type 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STAT5A signal transducer and activator of transcription 5A
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THSD4 thrombospondin, type I, domain containing 4
TLR2 toll-like receptor 2
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TSGA10 testis specific, 10
TUBA4B tubulin, alpha 4b
TUBA8 tubulin, alpha 8
UPK3A uroplakin 3A
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZNF141 zinc finger protein 141