CP-320650-01-4382 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the CP-320650-01-4382 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APOC1 apolipoprotein C-I
ATN1 atrophin 1
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BAX BCL2-associated X protein
BCL2L10 BCL2-like 10 (apoptosis facilitator)
C11ORF30 chromosome 11 open reading frame 30
CARD9 caspase recruitment domain family, member 9
CD58 CD58 molecule
CDK13 cyclin-dependent kinase 13
CDK18 cyclin-dependent kinase 18
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CPA4 carboxypeptidase A4
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DGCR8 DGCR8 microprocessor complex subunit
ECE1 endothelin converting enzyme 1
ECM1 extracellular matrix protein 1
EFS embryonal Fyn-associated substrate
EMCN endomucin
EN2 engrailed homeobox 2
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FGF6 fibroblast growth factor 6
FMO5 flavin containing monooxygenase 5
FRZB frizzled-related protein
G6PC2 glucose-6-phosphatase, catalytic, 2
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
HBB hemoglobin, beta
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HFE hemochromatosis
HIC2 hypermethylated in cancer 2
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HP haptoglobin
ICOSLG inducible T-cell co-stimulator ligand
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA7 integrin, alpha 7
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
JUN jun proto-oncogene
KCNK12 potassium channel, two pore domain subfamily K, member 12
KDM4B lysine (K)-specific demethylase 4B
KIAA0125 KIAA0125
KMT2A lysine (K)-specific methyltransferase 2A
LIMK1 LIM domain kinase 1
LMNB1 lamin B1
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LYZL6 lysozyme-like 6
MBD2 methyl-CpG binding domain protein 2
MIER2 mesoderm induction early response 1, family member 2
MPP1 membrane protein, palmitoylated 1, 55kDa
MUC3B mucin 3B, cell surface associated
MXD4 MAX dimerization protein 4
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
OR10J1 olfactory receptor, family 10, subfamily J, member 1
PCDHGA8 protocadherin gamma subfamily A, 8
PHF20L1 PHD finger protein 20-like 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTPRM protein tyrosine phosphatase, receptor type, M
RABGAP1 RAB GTPase activating protein 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SARM1 sterile alpha and TIR motif containing 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERHL2 serine hydrolase-like 2
SH3GL3 SH3-domain GRB2-like 3
SHOX2 short stature homeobox 2
SIM2 single-minded family bHLH transcription factor 2
SIRT4 sirtuin 4
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SOX15 SRY (sex determining region Y)-box 15
SPTBN1 spectrin, beta, non-erythrocytic 1
STARD8 StAR-related lipid transfer (START) domain containing 8
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAS2R4 taste receptor, type 2, member 4
TBX3 T-box 3
TCF25 transcription factor 25 (basic helix-loop-helix)
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRPC4 transient receptor potential cation channel, subfamily C, member 4
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
USP2 ubiquitin specific peptidase 2
USP22 ubiquitin specific peptidase 22
USP53 ubiquitin specific peptidase 53
YTHDC2 YTH domain containing 2
ZNF236 zinc finger protein 236
ZNF358 zinc finger protein 358

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APOC4 apolipoprotein C-IV
ARMC4 armadillo repeat containing 4
ATP10D ATPase, class V, type 10D
AUTS2 autism susceptibility candidate 2
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C11ORF16 chromosome 11 open reading frame 16
C1ORF54 chromosome 1 open reading frame 54
CASC1 cancer susceptibility candidate 1
CCDC134 coiled-coil domain containing 134
CD79B CD79b molecule, immunoglobulin-associated beta
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DLK2 delta-like 2 homolog (Drosophila)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DYSF dysferlin
EPN1 epsin 1
FFAR2 free fatty acid receptor 2
FGF22 fibroblast growth factor 22
FKRP fukutin related protein
FSHB follicle stimulating hormone, beta polypeptide
FSTL1 follistatin-like 1
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GALR2 galanin receptor 2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPATCH2L G patch domain containing 2-like
GPR143 G protein-coupled receptor 143
GSTTP1 glutathione S-transferase theta pseudogene 1
HCG4 HLA complex group 4 (non-protein coding)
HIST1H2BO histone cluster 1, H2bo
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IDI2-AS1 IDI2 antisense RNA 1
IFI27 interferon, alpha-inducible protein 27
IL12RB1 interleukin 12 receptor, beta 1
IL2 interleukin 2
IL2RG interleukin 2 receptor, gamma
INPP1 inositol polyphosphate-1-phosphatase
ISL1 ISL LIM homeobox 1
KERA keratocan
KIAA0754 KIAA0754
KIAA1324 KIAA1324
KLHL25 kelch-like family member 25
KRT83 keratin 83, type II
LGALS9 lectin, galactoside-binding, soluble, 9
LRRTM2 leucine rich repeat transmembrane neuronal 2
LTBP2 latent transforming growth factor beta binding protein 2
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAL mal, T-cell differentiation protein
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MMP3 matrix metallopeptidase 3
MXRA8 matrix-remodelling associated 8
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NAG18 NAG18 mRNA
NOL12 nucleolar protein 12
NRTN neurturin
NTF3 neurotrophin 3
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PARP11 poly (ADP-ribose) polymerase family, member 11
PCDHGB6 protocadherin gamma subfamily B, 6
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PIPOX pipecolic acid oxidase
PRAMEF10 PRAME family member 10
PROL1 proline rich, lacrimal 1
PSAT1 phosphoserine aminotransferase 1
PTX3 pentraxin 3, long
PWAR5 Prader Willi/Angelman region RNA 5
RAB3A RAB3A, member RAS oncogene family
RPS4Y1 ribosomal protein S4, Y-linked 1
RSG1 REM2 and RAB-like small GTPase 1
RUSC2 RUN and SH3 domain containing 2
S100A7 S100 calcium binding protein A7
SAMHD1 SAM domain and HD domain 1
SAYSD1 SAYSVFN motif domain containing 1
SECTM1 secreted and transmembrane 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SNCAIP synuclein, alpha interacting protein
SPTBN2 spectrin, beta, non-erythrocytic 2
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TBC1D2 TBC1 domain family, member 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TM4SF5 transmembrane 4 L six family member 5
TONSL tonsoku-like, DNA repair protein
TRIM68 tripartite motif containing 68
USP27X ubiquitin specific peptidase 27, X-linked
VIPR1 vasoactive intestinal peptide receptor 1
ZFHX4 zinc finger homeobox 4
ZMAT4 zinc finger, matrin-type 4
ZNF41 zinc finger protein 41
ZNF711 zinc finger protein 711