CP-320650-01-3825 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the CP-320650-01-3825 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ADPRH ADP-ribosylarginine hydrolase
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ANGEL2 angel homolog 2 (Drosophila)
ANGPTL2 angiopoietin-like 2
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
ATN1 atrophin 1
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
B9D2 B9 protein domain 2
BATF basic leucine zipper transcription factor, ATF-like
C14ORF79 chromosome 14 open reading frame 79
C2CD2L C2CD2-like
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCDC181 coiled-coil domain containing 181
CD52 CD52 molecule
CD80 CD80 molecule
CGA glycoprotein hormones, alpha polypeptide
CLEC1B C-type lectin domain family 1, member B
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CREBZF CREB/ATF bZIP transcription factor
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DLGAP2 discs, large (Drosophila) homolog-associated protein 2
DOK4 docking protein 4
EXO5 exonuclease 5
FABP6 fatty acid binding protein 6, ileal
FGL2 fibrinogen-like 2
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GFI1 growth factor independent 1 transcription repressor
GJA9 gap junction protein, alpha 9, 59kDa
GPR20 G protein-coupled receptor 20
GRIP2 glutamate receptor interacting protein 2
GYPB glycophorin B (MNS blood group)
HCRTR2 hypocretin (orexin) receptor 2
HFE hemochromatosis
HIF3A hypoxia inducible factor 3, alpha subunit
ICAM2 intercellular adhesion molecule 2
IGF2-AS IGF2 antisense RNA
INPP5J inositol polyphosphate-5-phosphatase J
ITGB8 integrin, beta 8
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KLF12 Kruppel-like factor 12
KLHL11 kelch-like family member 11
KLK2 kallikrein-related peptidase 2
KLRC3 killer cell lectin-like receptor subfamily C, member 3
KRT85 keratin 85, type II
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LCAT lecithin-cholesterol acyltransferase
LDB3 LIM domain binding 3
LINC00312 long intergenic non-protein coding RNA 312
LIPE lipase, hormone-sensitive
LOC100131532 uncharacterized LOC100131532
LRRN3 leucine rich repeat neuronal 3
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAGEC3 melanoma antigen family C3
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MEPE matrix extracellular phosphoglycoprotein
MMRN1 multimerin 1
MTCP1 mature T-cell proliferation 1
MUC8 mucin 8
MYO1F myosin IF
MYT1 myelin transcription factor 1
NRCAM neuronal cell adhesion molecule
NUMA1 nuclear mitotic apparatus protein 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PLA2G1B phospholipase A2, group IB (pancreas)
PML promyelocytic leukemia
PRDM9 PR domain containing 9
PTGDR2 prostaglandin D2 receptor 2
RAB26 RAB26, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RPS4Y1 ribosomal protein S4, Y-linked 1
SERGEF secretion regulating guanine nucleotide exchange factor
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC17A2 solute carrier family 17, member 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SNTG1 syntrophin, gamma 1
SORBS1 sorbin and SH3 domain containing 1
SPATA1 spermatogenesis associated 1
SPATA6 spermatogenesis associated 6
SPTBN5 spectrin, beta, non-erythrocytic 5
TAOK2 TAO kinase 2
TCF7 transcription factor 7 (T-cell specific, HMG-box)
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP73-AS1 TP73 antisense RNA 1
TPP1 tripeptidyl peptidase I
TSPAN8 tetraspanin 8
TXNRD2 thioredoxin reductase 2
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
WFDC2 WAP four-disulfide core domain 2
WNT1 wingless-type MMTV integration site family, member 1
YBX2 Y box binding protein 2

decreased expression

Symbol Name
ACSS3 acyl-CoA synthetase short-chain family member 3
ADAM23 ADAM metallopeptidase domain 23
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ANGPT4 angiopoietin 4
ARMCX4 armadillo repeat containing, X-linked 4
ART1 ADP-ribosyltransferase 1
BCAS1 breast carcinoma amplified sequence 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BEGAIN brain-enriched guanylate kinase-associated
C17ORF70 chromosome 17 open reading frame 70
C1RL complement component 1, r subcomponent-like
CAMKMT calmodulin-lysine N-methyltransferase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC132 coiled-coil domain containing 132
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD101 CD101 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD79A CD79a molecule, immunoglobulin-associated alpha
CD82 CD82 molecule
CDH19 cadherin 19, type 2
CLCN6 chloride channel, voltage-sensitive 6
CLDN8 claudin 8
CLEC4E C-type lectin domain family 4, member E
CLSTN3 calsyntenin 3
CPNE7 copine VII
CREB5 cAMP responsive element binding protein 5
DDN dendrin
DIO3 deiodinase, iodothyronine, type III
DNASE1L3 deoxyribonuclease I-like 3
ELAC1 elaC ribonuclease Z 1
FAM46C family with sequence similarity 46, member C
FOS FBJ murine osteosarcoma viral oncogene homolog
FSHB follicle stimulating hormone, beta polypeptide
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GK3P glycerol kinase 3 pseudogene
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR75 G protein-coupled receptor 75
GRTP1 growth hormone regulated TBC protein 1
HDAC11 histone deacetylase 11
HIST1H4E histone cluster 1, H4e
IFNA14 interferon, alpha 14
IFNA17 interferon, alpha 17
IL2 interleukin 2
IL22 interleukin 22
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KLF13 Kruppel-like factor 13
KLHL25 kelch-like family member 25
KRT9 keratin 9, type I
LGALS4 lectin, galactoside-binding, soluble, 4
LIMD2 LIM domain containing 2
LINC00260 long intergenic non-protein coding RNA 260
LPPR1 lipid phosphate phosphatase-related protein type 1
LYRM9 LYR motif containing 9
MAGEA12 melanoma antigen family A12
MMP13 matrix metallopeptidase 13
MMRN2 multimerin 2
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NCALD neurocalcin delta
NEUROD1 neuronal differentiation 1
NKX3-2 NK3 homeobox 2
NPIPB15 nuclear pore complex interacting protein family, member B15
NPIPB3 nuclear pore complex interacting protein family, member B3
NR1H4 nuclear receptor subfamily 1, group H, member 4
NTNG1 netrin G1
NYNRIN NYN domain and retroviral integrase containing
PADI1 peptidyl arginine deiminase, type I
PALM paralemmin
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POLL polymerase (DNA directed), lambda
PRAF2 PRA1 domain family, member 2
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RGS17 regulator of G-protein signaling 17
RNF122 ring finger protein 122
SCNN1B sodium channel, non voltage gated 1 beta subunit
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SLCO5A1 solute carrier organic anion transporter family, member 5A1
SLITRK5 SLIT and NTRK-like family, member 5
SLMO1 slowmo homolog 1 (Drosophila)
SMO smoothened, frizzled class receptor
ST7L suppression of tumorigenicity 7 like
STXBP5L syntaxin binding protein 5-like
SYT17 synaptotagmin XVII
TAGLN3 transgelin 3
TMEM132A transmembrane protein 132A
TMEM206 transmembrane protein 206
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
VASP vasodilator-stimulated phosphoprotein
VNN1 vanin 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XDH xanthine dehydrogenase
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZNF155 zinc finger protein 155
ZNF408 zinc finger protein 408
ZNF446 zinc finger protein 446
ZNF506 zinc finger protein 506
ZNF528 zinc finger protein 528
ZNF549 zinc finger protein 549
ZNF639 zinc finger protein 639