CP-319743-7532 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the CP-319743-7532 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ACAN aggrecan
ADAM22 ADAM metallopeptidase domain 22
APOL3 apolipoprotein L, 3
ARNT aryl hydrocarbon receptor nuclear translocator
ATF7IP activating transcription factor 7 interacting protein
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BTNL3 butyrophilin-like 3
C1QTNF1 C1q and tumor necrosis factor related protein 1
CA4 carbonic anhydrase IV
CABP1 calcium binding protein 1
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CD58 CD58 molecule
CDC5L cell division cycle 5-like
CDK19 cyclin-dependent kinase 19
CDKL3 cyclin-dependent kinase-like 3
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEP250 centrosomal protein 250kDa
CES1 carboxylesterase 1
CFAP44 cilia and flagella associated protein 44
CLCA1 chloride channel accessory 1
CNOT3 CCR4-NOT transcription complex, subunit 3
COL9A3 collagen, type IX, alpha 3
CSHL1 chorionic somatomammotropin hormone-like 1
CTRC chymotrypsin C (caldecrin)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DEPDC5 DEP domain containing 5
DIAPH2 diaphanous-related formin 2
DNAH3 dynein, axonemal, heavy chain 3
DZIP3 DAZ interacting zinc finger protein 3
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
EPHB4 EPH receptor B4
EVA1B eva-1 homolog B (C. elegans)
FAXDC2 fatty acid hydroxylase domain containing 2
FBXO2 F-box protein 2
FLI1 Fli-1 proto-oncogene, ETS transcription factor
GAS2 growth arrest-specific 2
HIST1H2AI histone cluster 1, H2ai
HIST1H2AK histone cluster 1, H2ak
IFT27 intraflagellar transport 27
IL12RB1 interleukin 12 receptor, beta 1
IL1B interleukin 1, beta
ING4 inhibitor of growth family, member 4
IQCE IQ motif containing E
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KLF12 Kruppel-like factor 12
KRT75 keratin 75, type II
KRTAP1-3 keratin associated protein 1-3
LAMC2 laminin, gamma 2
LAMP1 lysosomal-associated membrane protein 1
LOX lysyl oxidase
LYST lysosomal trafficking regulator
MATK megakaryocyte-associated tyrosine kinase
MFGE8 milk fat globule-EGF factor 8 protein
MID1 midline 1
MMP25 matrix metallopeptidase 25
MTSS1L metastasis suppressor 1-like
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NF2 neurofibromin 2 (merlin)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUMA1 nuclear mitotic apparatus protein 1
NUP188 nucleoporin 188kDa
OR51E2 olfactory receptor, family 51, subfamily E, member 2
ORAI2 ORAI calcium release-activated calcium modulator 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE8B phosphodiesterase 8B
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLEKHO2 pleckstrin homology domain containing, family O member 2
PTGES prostaglandin E synthase
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAD51 RAD51 recombinase
REM1 RAS (RAD and GEM)-like GTP-binding 1
RIF1 replication timing regulatory factor 1
RNF6 ring finger protein (C3H2C3 type) 6
RPL35A ribosomal protein L35a
RUNX1 runt-related transcription factor 1
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SOCS3 suppressor of cytokine signaling 3
STMN3 stathmin-like 3
SYNDIG1 synapse differentiation inducing 1
SYNGR1 synaptogyrin 1
TIMP3 TIMP metallopeptidase inhibitor 3
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNS1 tensin 1
TRIM23 tripartite motif containing 23
VPS9D1 VPS9 domain containing 1
WIPI2 WD repeat domain, phosphoinositide interacting 2
ZDHHC17 zinc finger, DHHC-type containing 17
ZFPL1 zinc finger protein-like 1
ZNF250 zinc finger protein 250

decreased expression

Symbol Name
AFAP1 actin filament associated protein 1
ARSB arylsulfatase B
BAG4 BCL2-associated athanogene 4
BRSK2 BR serine/threonine kinase 2
C2CD2 C2 calcium-dependent domain containing 2
C3ORF52 chromosome 3 open reading frame 52
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMTA1 calmodulin binding transcription activator 1
CDK20 cyclin-dependent kinase 20
CEL carboxyl ester lipase
CHST10 carbohydrate sulfotransferase 10
CLCN5 chloride channel, voltage-sensitive 5
CUL9 cullin 9
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DLK2 delta-like 2 homolog (Drosophila)
EHMT1 euchromatic histone-lysine N-methyltransferase 1
FAM120C family with sequence similarity 120C
FAM135A family with sequence similarity 135, member A
FAM155A family with sequence similarity 155, member A
FSTL3 follistatin-like 3 (secreted glycoprotein)
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GLCE glucuronic acid epimerase
GMEB1 glucocorticoid modulatory element binding protein 1
GPX2 glutathione peroxidase 2
GRTP1 growth hormone regulated TBC protein 1
HCK HCK proto-oncogene, Src family tyrosine kinase
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
IFNA17 interferon, alpha 17
IFNA21 interferon, alpha 21
IFT22 intraflagellar transport 22
IL17RA interleukin 17 receptor A
KCTD15 potassium channel tetramerization domain containing 15
KREMEN2 kringle containing transmembrane protein 2
KRT15 keratin 15, type I
LINC00652 long intergenic non-protein coding RNA 652
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MEGF8 multiple EGF-like-domains 8
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
MTCP1 mature T-cell proliferation 1
MYL5 myosin, light chain 5, regulatory
NEK11 NIMA-related kinase 11
NRGN neurogranin (protein kinase C substrate, RC3)
NRTN neurturin
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
NXPH3 neurexophilin 3
PAIP2B poly(A) binding protein interacting protein 2B
PALM paralemmin
PCDHA6 protocadherin alpha 6
PDE9A phosphodiesterase 9A
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PNPLA2 patatin-like phospholipase domain containing 2
PODXL2 podocalyxin-like 2
PQLC2 PQ loop repeat containing 2
PRKG2 protein kinase, cGMP-dependent, type II
PROL1 proline rich, lacrimal 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRSS2 protease, serine, 2 (trypsin 2)
PTPRG protein tyrosine phosphatase, receptor type, G
RAP1GAP2 RAP1 GTPase activating protein 2
RNF122 ring finger protein 122
RNF170 ring finger protein 170
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RWDD3 RWD domain containing 3
SCN1B sodium channel, voltage gated, type I beta subunit
SKA1 spindle and kinetochore associated complex subunit 1
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC22A14 solute carrier family 22, member 14
SLC35F5 solute carrier family 35, member F5
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SOAT2 sterol O-acyltransferase 2
STAB2 stabilin 2
STIM1 stromal interaction molecule 1
TCTN1 tectonic family member 1
THRAP3 thyroid hormone receptor associated protein 3
TMEM165 transmembrane protein 165
TMEM209 transmembrane protein 209
TMEM212 transmembrane protein 212
TMEM8B transmembrane protein 8B
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNNI3 troponin I type 3 (cardiac)
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
USB1 U6 snRNA biogenesis 1
VEGFB vascular endothelial growth factor B
XK X-linked Kx blood group
ZDHHC14 zinc finger, DHHC-type containing 14
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF10 zinc finger protein 10
ZNF205 zinc finger protein 205
ZNF492 zinc finger protein 492
ZNF606 zinc finger protein 606