CP-319743-7486 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the CP-319743-7486 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ADAM7 ADAM metallopeptidase domain 7
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AHI1 Abelson helper integration site 1
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOLD1 apolipoprotein L domain containing 1
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARNT aryl hydrocarbon receptor nuclear translocator
ARRB1 arrestin, beta 1
ATP2A3 ATPase, Ca++ transporting, ubiquitous
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CARD9 caspase recruitment domain family, member 9
CASP8 caspase 8, apoptosis-related cysteine peptidase
CHRM3 cholinergic receptor, muscarinic 3
CLCN6 chloride channel, voltage-sensitive 6
CLTC clathrin, heavy chain (Hc)
COPA coatomer protein complex, subunit alpha
CRMP1 collapsin response mediator protein 1
CRYM crystallin, mu
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DNAAF1 dynein, axonemal, assembly factor 1
ECE1 endothelin converting enzyme 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ESR1 estrogen receptor 1
FEM1B fem-1 homolog b (C. elegans)
FLOT1 flotillin 1
FLOT2 flotillin 2
FNTB farnesyltransferase, CAAX box, beta
GADD45G growth arrest and DNA-damage-inducible, gamma
GFI1 growth factor independent 1 transcription repressor
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPER1 G protein-coupled estrogen receptor 1
GPR143 G protein-coupled receptor 143
GYG2 glycogenin 2
HBP1 HMG-box transcription factor 1
HP1BP3 heterochromatin protein 1, binding protein 3
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KIF21B kinesin family member 21B
LARP7 La ribonucleoprotein domain family, member 7
LCT lactase
LHX2 LIM homeobox 2
LTBP4 latent transforming growth factor beta binding protein 4
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED25 mediator complex subunit 25
MEF2D myocyte enhancer factor 2D
MFGE8 milk fat globule-EGF factor 8 protein
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MST1 macrophage stimulating 1
MST1L macrophage stimulating 1-like
MTL5 metallothionein-like 5, testis-specific (tesmin)
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NECAB2 N-terminal EF-hand calcium binding protein 2
NOD2 nucleotide-binding oligomerization domain containing 2
NPIPB3 nuclear pore complex interacting protein family, member B3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUDCD3 NudC domain containing 3
OGFR opioid growth factor receptor
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE3B phosphodiesterase 3B, cGMP-inhibited
PILRA paired immunoglobin-like type 2 receptor alpha
PKP2 plakophilin 2
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAB40AL RAB40A, member RAS oncogene family-like
RASAL1 RAS protein activator like 1 (GAP1 like)
REM1 RAS (RAD and GEM)-like GTP-binding 1
RNF6 ring finger protein (C3H2C3 type) 6
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SAP30 Sin3A-associated protein, 30kDa
SCRN3 secernin 3
SETD8 SET domain containing (lysine methyltransferase) 8
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SNX13 sorting nexin 13
SRD5A3 steroid 5 alpha-reductase 3
STMN1 stathmin 1
STS steroid sulfatase (microsomal), isozyme S
SUSD5 sushi domain containing 5
TMED2 transmembrane emp24 domain trafficking protein 2
TMEM259 transmembrane protein 259
TRIM23 tripartite motif containing 23
TRIO trio Rho guanine nucleotide exchange factor
USP27X ubiquitin specific peptidase 27, X-linked
VEGFA vascular endothelial growth factor A
WSCD1 WSC domain containing 1
ZNF350 zinc finger protein 350
ZNF783 zinc finger family member 783
ZSCAN31 zinc finger and SCAN domain containing 31

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACPP acid phosphatase, prostate
ADGRB1 adhesion G protein-coupled receptor B1
ADGRE5 adhesion G protein-coupled receptor E5
AFAP1 actin filament associated protein 1
AHNAK2 AHNAK nucleoprotein 2
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ART1 ADP-ribosyltransferase 1
ASB9 ankyrin repeat and SOCS box containing 9
ATAD5 ATPase family, AAA domain containing 5
ATAT1 alpha tubulin acetyltransferase 1
BAG4 BCL2-associated athanogene 4
BARX2 BARX homeobox 2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C14ORF79 chromosome 14 open reading frame 79
C17ORF53 chromosome 17 open reading frame 53
C2ORF27A chromosome 2 open reading frame 27A
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCDC121 coiled-coil domain containing 121
CD48 CD48 molecule
CERS4 ceramide synthase 4
CLCN5 chloride channel, voltage-sensitive 5
CLGN calmegin
CNTFR ciliary neurotrophic factor receptor
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DEFA4 defensin, alpha 4, corticostatin
DPF1 D4, zinc and double PHD fingers family 1
FLRT3 fibronectin leucine rich transmembrane protein 3
GJA8 gap junction protein, alpha 8, 50kDa
GMEB1 glucocorticoid modulatory element binding protein 1
GMPR guanosine monophosphate reductase
GPR157 G protein-coupled receptor 157
GRPR gastrin-releasing peptide receptor
HDAC5 histone deacetylase 5
HIST1H2AI histone cluster 1, H2ai
HIST1H2BM histone cluster 1, H2bm
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXA3 homeobox A3
HSPA1L heat shock 70kDa protein 1-like
HYI hydroxypyruvate isomerase (putative)
IFI35 interferon-induced protein 35
IKZF5 IKAROS family zinc finger 5 (Pegasus)
INO80D INO80 complex subunit D
JMJD4 jumonji domain containing 4
JRKL JRK-like
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LIN7B lin-7 homolog B (C. elegans)
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAK male germ cell-associated kinase
MFSD11 major facilitator superfamily domain containing 11
MGC2889 uncharacterized protein MGC2889
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NIPAL3 NIPA-like domain containing 3
NRDE2 NRDE-2, necessary for RNA interference, domain containing
ONECUT2 one cut homeobox 2
PADI3 peptidyl arginine deiminase, type III
PAQR4 progestin and adipoQ receptor family member IV
PCDHA5 protocadherin alpha 5
PLCD1 phospholipase C, delta 1
PODNL1 podocan-like 1
PTDSS2 phosphatidylserine synthase 2
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RASIP1 Ras interacting protein 1
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RLN1 relaxin 1
RNF122 ring finger protein 122
S100A9 S100 calcium binding protein A9
SAYSD1 SAYSVFN motif domain containing 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SETD1A SET domain containing 1A
SIRT6 sirtuin 6
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC22A14 solute carrier family 22, member 14
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
STXBP5L syntaxin binding protein 5-like
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TCTN2 tectonic family member 2
THNSL2 threonine synthase-like 2 (S. cerevisiae)
THRAP3 thyroid hormone receptor associated protein 3
TMCC2 transmembrane and coiled-coil domain family 2
TMEM127 transmembrane protein 127
TMPRSS3 transmembrane protease, serine 3
TRAIP TRAF interacting protein
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCN urocortin
UNC119 unc-119 homolog (C. elegans)
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF137P zinc finger protein 137, pseudogene
ZNF324 zinc finger protein 324
ZNF35 zinc finger protein 35
ZNF365 zinc finger protein 365
ZNF492 zinc finger protein 492
ZNF76 zinc finger protein 76
ZNF787 zinc finger protein 787