CML - Chronic myeloid leukemia_Haematopoietic stem cell_GSE11889 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE11889
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Genes

600 genes differentially expressed during CML - Chronic myeloid leukemia_Haematopoietic stem cell_GSE11889 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
BTK Bruton agammaglobulinemia tyrosine kinase 3.19483
LEPR leptin receptor 2.90499
PDLIM1 PDZ and LIM domain 1 2.64079
SELPLG selectin P ligand 2.62688
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 2.606
ATXN7L3B ataxin 7-like 3B 2.55034
MARCKS myristoylated alanine-rich protein kinase C substrate 2.42856
SRSF1 serine/arginine-rich splicing factor 1 2.42811
GAPVD1 GTPase activating protein and VPS9 domains 1 2.39828
WNK1 WNK lysine deficient protein kinase 1 2.35168
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 2.35108
BMP2K BMP2 inducible kinase 2.32752
SEPT7 septin 7 2.32187
SH2B1 SH2B adaptor protein 1 2.31301
HDAC3 histone deacetylase 3 2.28298
SFI1 Sfi1 homolog, spindle assembly associated (yeast) 2.22388
UBE2G2 ubiquitin-conjugating enzyme E2G 2 2.20859
PDE4C phosphodiesterase 4C, cAMP-specific 2.19733
SERTAD4 SERTA domain containing 4 2.17928
RBMX2 RNA binding motif protein, X-linked 2 2.16142
FAM222B family with sequence similarity 222, member B 2.15186
FDFT1 farnesyl-diphosphate farnesyltransferase 1 2.14777
FBXO9 F-box protein 9 2.10004
HEATR6 HEAT repeat containing 6 2.09501
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 2.09403
DNMT1 DNA (cytosine-5-)-methyltransferase 1 2.08699
RIOK3 RIO kinase 3 2.07251
RPL10 ribosomal protein L10 2.06908
MAP2K3 mitogen-activated protein kinase kinase 3 2.00376
GRB10 growth factor receptor-bound protein 10 2.00112
DLC1 DLC1 Rho GTPase activating protein 1.98926
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 1.98491
INTS3 integrator complex subunit 3 1.9826
GAS2 growth arrest-specific 2 1.96861
PRDM2 PR domain containing 2, with ZNF domain 1.95881
MRPL9 mitochondrial ribosomal protein L9 1.95108
PABPN1 poly(A) binding protein, nuclear 1 1.9476
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 1.94759
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1.92564
MYL4 myosin, light chain 4, alkali; atrial, embryonic 1.92446
GSE1 Gse1 coiled-coil protein 1.92262
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 1.91518
ATXN3 ataxin 3 1.90477
GNS glucosamine (N-acetyl)-6-sulfatase 1.90183
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 1.89938
ZNF444 zinc finger protein 444 1.89748
ADGRL1 adhesion G protein-coupled receptor L1 1.89661
CBR4 carbonyl reductase 4 1.88435
EIF5B eukaryotic translation initiation factor 5B 1.88247
NFIB nuclear factor I/B 1.88219
SLC35E1 solute carrier family 35, member E1 1.87845
LGALS8 lectin, galactoside-binding, soluble, 8 1.87782
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) 1.87605
CSNK1D casein kinase 1, delta 1.8749
RNF19B ring finger protein 19B 1.86328
PEA15 phosphoprotein enriched in astrocytes 15 1.86147
TAL1 T-cell acute lymphocytic leukemia 1 1.86104
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.86003
CFHR1 complement factor H-related 1 1.8559
SLC48A1 solute carrier family 48 (heme transporter), member 1 1.85475
C21ORF33 chromosome 21 open reading frame 33 1.85413
USP48 ubiquitin specific peptidase 48 1.85153
OSBPL9 oxysterol binding protein-like 9 1.83931
MPPE1 metallophosphoesterase 1 1.8373
BRD2 bromodomain containing 2 1.83292
CASC3 cancer susceptibility candidate 3 1.82942
ZNF212 zinc finger protein 212 1.82932
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.82026
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 1.81397
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 1.81352
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 1.81345
PLXND1 plexin D1 1.80972
CAPRIN2 caprin family member 2 1.80912
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 1.80592
SERTAD3 SERTA domain containing 3 1.80467
RECK reversion-inducing-cysteine-rich protein with kazal motifs 1.79845
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 1.79733
SCP2 sterol carrier protein 2 1.78734
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 1.7858
FLOT1 flotillin 1 1.78064
SSRP1 structure specific recognition protein 1 1.7776
ICAM1 intercellular adhesion molecule 1 1.7754
MYH10 myosin, heavy chain 10, non-muscle 1.77517
PREPL prolyl endopeptidase-like 1.76621
SNX5 sorting nexin 5 1.76505
ELF2 E74-like factor 2 (ets domain transcription factor) 1.76297
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 1.76296
NOL9 nucleolar protein 9 1.75707
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 1.75514
TRIAP1 TP53 regulated inhibitor of apoptosis 1 1.75032
SPINT2 serine peptidase inhibitor, Kunitz type, 2 1.74416
ANGEL2 angel homolog 2 (Drosophila) 1.74132
LPAR3 lysophosphatidic acid receptor 3 1.74058
MORC2 MORC family CW-type zinc finger 2 1.739
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 1.73506
AIP aryl hydrocarbon receptor interacting protein 1.73339
FBXO7 F-box protein 7 1.7295
IFITM1 interferon induced transmembrane protein 1 1.72832
C14ORF1 chromosome 14 open reading frame 1 1.72707
ITSN2 intersectin 2 1.7266
ST7L suppression of tumorigenicity 7 like 1.72517
SMAD4 SMAD family member 4 1.72396
MAP7 microtubule-associated protein 7 1.72332
CREBZF CREB/ATF bZIP transcription factor 1.72213
ELOVL6 ELOVL fatty acid elongase 6 1.71903
HIC2 hypermethylated in cancer 2 1.71891
PRKD2 protein kinase D2 1.71519
ACTR10 actin-related protein 10 homolog (S. cerevisiae) 1.71318
GAS7 growth arrest-specific 7 1.71298
ANXA2 annexin A2 1.71295
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 1.70825
EPRS glutamyl-prolyl-tRNA synthetase 1.70772
TJAP1 tight junction associated protein 1 (peripheral) 1.70456
RGS12 regulator of G-protein signaling 12 1.69995
CNOT4 CCR4-NOT transcription complex, subunit 4 1.6998
JAM3 junctional adhesion molecule 3 1.6994
LONRF3 LON peptidase N-terminal domain and ring finger 3 1.69907
MASP2 mannan-binding lectin serine peptidase 2 1.69641
SIAH1 siah E3 ubiquitin protein ligase 1 1.69387
ZNF587 zinc finger protein 587 1.69374
TMEM183A transmembrane protein 183A 1.69354
ARRDC1 arrestin domain containing 1 1.69343
ZXDC ZXD family zinc finger C 1.69223
LST1 leukocyte specific transcript 1 1.69221
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 1.69203
HDDC2 HD domain containing 2 1.69171
ZNF224 zinc finger protein 224 1.68887
AKAP9 A kinase (PRKA) anchor protein 9 1.68844
PREP prolyl endopeptidase 1.68819
ANAPC5 anaphase promoting complex subunit 5 1.68725
ZNF408 zinc finger protein 408 1.68529
GOLGA8B golgin A8 family, member B 1.68159
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A 1.67901
KIAA0391 KIAA0391 1.67858
TBCD tubulin folding cofactor D 1.67815
FBXO46 F-box protein 46 1.6775
PPIG peptidylprolyl isomerase G (cyclophilin G) 1.67621
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 1.67615
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 1.67327
TGOLN2 trans-golgi network protein 2 1.67253
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 1.6698
COPS6 COP9 signalosome subunit 6 1.66722
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa 1.66681
ITFG2 integrin alpha FG-GAP repeat containing 2 1.66515
PDE4DIP phosphodiesterase 4D interacting protein 1.6647
ENOSF1 enolase superfamily member 1 1.66174
CSNK1G2 casein kinase 1, gamma 2 1.6597
CNN2 calponin 2 1.64908
CHN2 chimerin 2 1.64661
TULP3 tubby like protein 3 1.64589
PARN poly(A)-specific ribonuclease 1.64428
CHD4 chromodomain helicase DNA binding protein 4 1.64249
TACSTD2 tumor-associated calcium signal transducer 2 1.64168
TBC1D4 TBC1 domain family, member 4 1.64051
NAP1L4 nucleosome assembly protein 1-like 4 1.64049
HMBS hydroxymethylbilane synthase 1.63934
IL1R1 interleukin 1 receptor, type I 1.63901
C7ORF25 chromosome 7 open reading frame 25 1.63856
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 1.63744
BYSL bystin-like 1.63039
DNAH3 dynein, axonemal, heavy chain 3 1.62841
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 1.62814
PDCL phosducin-like 1.62524
ROGDI rogdi homolog (Drosophila) 1.62305
PRKX protein kinase, X-linked 1.62285
CUL5 cullin 5 1.61812
POLR2H polymerase (RNA) II (DNA directed) polypeptide H 1.61253
SRPK2 SRSF protein kinase 2 1.60877
CIITA class II, major histocompatibility complex, transactivator 1.60834
TPD52 tumor protein D52 1.60738
KLF6 Kruppel-like factor 6 1.6053
PFDN4 prefoldin subunit 4 1.60206
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) 1.60204
DVL3 dishevelled segment polarity protein 3 1.60161
CD81 CD81 molecule 1.59482
ATP7B ATPase, Cu++ transporting, beta polypeptide 1.59314
PARP6 poly (ADP-ribose) polymerase family, member 6 1.59194
NENF neudesin neurotrophic factor 1.59177
HIGD2A HIG1 hypoxia inducible domain family, member 2A 1.58991
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) 1.58882
PRPF18 pre-mRNA processing factor 18 1.58838
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1 1.58744
N4BP1 NEDD4 binding protein 1 1.58115
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 1.58051
FKBP4 FK506 binding protein 4, 59kDa 1.57505
LOC440434 aminopeptidase puromycin sensitive pseudogene 1.57491
FAM120A family with sequence similarity 120A 1.57416
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 1.57273
AHR aryl hydrocarbon receptor 1.57264
FANCE Fanconi anemia, complementation group E 1.57247
GLS glutaminase 1.57147
DSCR3 Down syndrome critical region 3 1.56369
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 1.5636
WDR13 WD repeat domain 13 1.56349
INVS inversin 1.56308
NLK nemo-like kinase 1.56135
ATG12 autophagy related 12 1.56016
RFC5 replication factor C (activator 1) 5, 36.5kDa 1.55997
ILVBL ilvB (bacterial acetolactate synthase)-like 1.55981
HMGXB4 HMG box domain containing 4 1.55803
TCF25 transcription factor 25 (basic helix-loop-helix) 1.55799
NPAT nuclear protein, ataxia-telangiectasia locus 1.54877
GYPB glycophorin B (MNS blood group) 1.54873
TRIOBP TRIO and F-actin binding protein 1.54724
CD59 CD59 molecule, complement regulatory protein 1.54714
CUL4B cullin 4B 1.54637
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit 1.54613
UBE2I ubiquitin-conjugating enzyme E2I 1.54405
TMEM214 transmembrane protein 214 1.53965
MGEA5 meningioma expressed antigen 5 (hyaluronidase) 1.53906
WDR6 WD repeat domain 6 1.53597
GPR161 G protein-coupled receptor 161 1.533
ADGRG1 adhesion G protein-coupled receptor G1 1.53185
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 1.52938
HTRA2 HtrA serine peptidase 2 1.52549
CXXC1 CXXC finger protein 1 1.51928
ZNF236 zinc finger protein 236 1.51801
FAM160B2 family with sequence similarity 160, member B2 1.51364
RAP2B RAP2B, member of RAS oncogene family 1.51305
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 1.51252
TGM2 transglutaminase 2 1.5097
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 1.5096
ELK1 ELK1, member of ETS oncogene family 1.50849
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 1.5078
LZTR1 leucine-zipper-like transcription regulator 1 1.50769
TNPO1 transportin 1 1.50688
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 1.50684
TSC2 tuberous sclerosis 2 1.50588
MID1 midline 1 1.50283
AATK apoptosis-associated tyrosine kinase 1.50232
MMP24 matrix metallopeptidase 24 (membrane-inserted) 1.49941
INTS7 integrator complex subunit 7 1.49795
THBD thrombomodulin 1.49787
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 1.49579
MYO1C myosin IC 1.49481
SF3B1 splicing factor 3b, subunit 1, 155kDa 1.49243
ZNF266 zinc finger protein 266 1.49199
ELL3 elongation factor RNA polymerase II-like 3 1.48782
VGLL4 vestigial-like family member 4 1.48762
FOLR1 folate receptor 1 (adult) 1.4867
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 1.48616
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 1.48573
RABEP2 rabaptin, RAB GTPase binding effector protein 2 1.48559
SNAP23 synaptosomal-associated protein, 23kDa 1.48432
EXOSC7 exosome component 7 1.4829
VAV1 vav 1 guanine nucleotide exchange factor 1.47963
CYB561 cytochrome b561 1.47815
UBN1 ubinuclein 1 1.4766
RGS10 regulator of G-protein signaling 10 1.47608
SNRPB2 small nuclear ribonucleoprotein polypeptide B 1.47346
MRPL42 mitochondrial ribosomal protein L42 1.4728
IVD isovaleryl-CoA dehydrogenase 1.47254
WDR55 WD repeat domain 55 1.47137
WBP4 WW domain binding protein 4 1.46911
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 1.46903
DDR2 discoidin domain receptor tyrosine kinase 2 1.46725
RBM19 RNA binding motif protein 19 1.46074
DGCR2 DiGeorge syndrome critical region gene 2 1.46004
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 1.45934
RUFY3 RUN and FYVE domain containing 3 1.45912
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.45671
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.45326
WWC3 WWC family member 3 1.45005
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.44912
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 1.44748
DOLPP1 dolichyldiphosphatase 1 1.44697
MAP3K11 mitogen-activated protein kinase kinase kinase 11 1.44356
HARS2 histidyl-tRNA synthetase 2, mitochondrial 1.44305
HRH1 histamine receptor H1 1.44287
ZMYND8 zinc finger, MYND-type containing 8 1.44255
TRIM33 tripartite motif containing 33 1.44236
ZDHHC3 zinc finger, DHHC-type containing 3 1.44144
GIPC1 GIPC PDZ domain containing family, member 1 1.44009
FXR2 fragile X mental retardation, autosomal homolog 2 1.43956
ALAD aminolevulinate dehydratase 1.4389
TSTA3 tissue specific transplantation antigen P35B 1.43882
EEF1G eukaryotic translation elongation factor 1 gamma 1.43841
WWP2 WW domain containing E3 ubiquitin protein ligase 2 1.43807
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) 1.43656
CACNB1 calcium channel, voltage-dependent, beta 1 subunit 1.43486
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 1.43473
ANGEL1 angel homolog 1 (Drosophila) 1.43469
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 1.43458
TACC1 transforming, acidic coiled-coil containing protein 1 1.43446
MYOZ3 myozenin 3 1.43423
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 1.43319
NBN nibrin 1.42999
STK17A serine/threonine kinase 17a 1.42845
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 1.42796
STAT2 signal transducer and activator of transcription 2, 113kDa 1.42791
WDR12 WD repeat domain 12 1.42516
HDGFRP3 hepatoma-derived growth factor, related protein 3 1.42496
ZNF134 zinc finger protein 134 1.42452
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 1.42309
ARID1A AT rich interactive domain 1A (SWI-like) 1.42291
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 1.42139
MEIS1 Meis homeobox 1 1.4193
NET1 neuroepithelial cell transforming 1 1.41853
CLCN7 chloride channel, voltage-sensitive 7 1.41837
SAMD4A sterile alpha motif domain containing 4A 1.41801

decreased expression

Symbol Name Standardized Value
MPHOSPH9 M-phase phosphoprotein 9 -2.76529
AREG amphiregulin -2.64192
APLP2 amyloid beta (A4) precursor-like protein 2 -2.59094
NAE1 NEDD8 activating enzyme E1 subunit 1 -2.52208
MCL1 myeloid cell leukemia 1 -2.5176
ACP1 acid phosphatase 1, soluble -2.45398
GADD45B growth arrest and DNA-damage-inducible, beta -2.40471
PTGER4 prostaglandin E receptor 4 (subtype EP4) -2.40338
C20ORF24 chromosome 20 open reading frame 24 -2.3935
CD44 CD44 molecule (Indian blood group) -2.34235
PRNP prion protein -2.332
CXCR4 chemokine (C-X-C motif) receptor 4 -2.32185
RPS26 ribosomal protein S26 -2.2796
HECA headcase homolog (Drosophila) -2.25129
EIF3J eukaryotic translation initiation factor 3, subunit J -2.23737
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta -2.21167
ERI2 ERI1 exoribonuclease family member 2 -2.20966
MPO myeloperoxidase -2.20455
EMP1 epithelial membrane protein 1 -2.16237
LMF2 lipase maturation factor 2 -2.15168
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 -2.13013
HAL histidine ammonia-lyase -2.1025
RB1 retinoblastoma 1 -2.10036
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -2.07726
RGS2 regulator of G-protein signaling 2 -2.07543
IGHM immunoglobulin heavy constant mu -2.07391
RAB2A RAB2A, member RAS oncogene family -2.06661
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -2.05932
MALT1 MALT1 paracaspase -2.05642
FANCA Fanconi anemia, complementation group A -2.04056
IRF8 interferon regulatory factor 8 -2.03173
SERTAD2 SERTA domain containing 2 -2.02926
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -2.02269
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa -2.01541
MAPK14 mitogen-activated protein kinase 14 -2.01158
PROM1 prominin 1 -1.99508
PI4KB phosphatidylinositol 4-kinase, catalytic, beta -1.99332
GLIPR1 GLI pathogenesis-related 1 -1.98877
API5 apoptosis inhibitor 5 -1.97747
FTH1 ferritin, heavy polypeptide 1 -1.97218
YLPM1 YLP motif containing 1 -1.96986
TMSB15A thymosin beta 15a -1.96106
SEC23A Sec23 homolog A (S. cerevisiae) -1.95728
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -1.95004
NR4A3 nuclear receptor subfamily 4, group A, member 3 -1.94752
NCOA1 nuclear receptor coactivator 1 -1.93711
IL17RC interleukin 17 receptor C -1.9134
MOSPD2 motile sperm domain containing 2 -1.90252
MAN1A1 mannosidase, alpha, class 1A, member 1 -1.90237
HLA-DMB major histocompatibility complex, class II, DM beta -1.89937
POLB polymerase (DNA directed), beta -1.89257
PAIP1 poly(A) binding protein interacting protein 1 -1.86932
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -1.86443
EXTL3 exostosin-like glycosyltransferase 3 -1.86089
HMGN2 high mobility group nucleosomal binding domain 2 -1.85368
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) -1.85248
FLT3 fms-related tyrosine kinase 3 -1.84916
SRPR signal recognition particle receptor (docking protein) -1.8491
EGR1 early growth response 1 -1.84719
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 -1.83742
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) -1.82743
SUMO2 small ubiquitin-like modifier 2 -1.82271
PRCC papillary renal cell carcinoma (translocation-associated) -1.82077
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -1.81813
CSNK2A1 casein kinase 2, alpha 1 polypeptide -1.81211
MAN1A2 mannosidase, alpha, class 1A, member 2 -1.81017
TRMT5 tRNA methyltransferase 5 -1.80888
ZFP36 ZFP36 ring finger protein -1.80626
FKBP6 FK506 binding protein 6, 36kDa -1.80449
EIF3H eukaryotic translation initiation factor 3, subunit H -1.80099
HCG4 HLA complex group 4 (non-protein coding) -1.79795
INSR insulin receptor -1.79494
FAM129A family with sequence similarity 129, member A -1.7903
HMGXB3 HMG box domain containing 3 -1.7884
TSC22D3 TSC22 domain family, member 3 -1.77952
AZIN1 antizyme inhibitor 1 -1.77811
CD47 CD47 molecule -1.77757
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -1.77635
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -1.7676
RPL35A ribosomal protein L35a -1.76737
PXDN peroxidasin -1.75685
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -1.75605
PER1 period circadian clock 1 -1.75476
ADA adenosine deaminase -1.74534
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -1.73723
SATB1 SATB homeobox 1 -1.73383
LAPTM5 lysosomal protein transmembrane 5 -1.7312
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -1.7277
TMEM97 transmembrane protein 97 -1.72728
TRIM44 tripartite motif containing 44 -1.72353
CRBN cereblon -1.72228
ZMYND11 zinc finger, MYND-type containing 11 -1.71711
JUN jun proto-oncogene -1.71336
TPM4 tropomyosin 4 -1.71327
GLUL glutamate-ammonia ligase -1.70498
UBE2J1 ubiquitin-conjugating enzyme E2, J1 -1.69921
NSD1 nuclear receptor binding SET domain protein 1 -1.69152
HSPA4 heat shock 70kDa protein 4 -1.69129
SRGN serglycin -1.69044
RPS17 ribosomal protein S17 -1.68494
UBL3 ubiquitin-like 3 -1.6832
PEX10 peroxisomal biogenesis factor 10 -1.683
IFI30 interferon, gamma-inducible protein 30 -1.67936
ZFPL1 zinc finger protein-like 1 -1.67208
AP2A2 adaptor-related protein complex 2, alpha 2 subunit -1.67182
CUL3 cullin 3 -1.67127
HOXA6 homeobox A6 -1.66938
TCF4 transcription factor 4 -1.65688
UBE4B ubiquitination factor E4B -1.65506
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -1.65312
FAM162A family with sequence similarity 162, member A -1.64551
IRS2 insulin receptor substrate 2 -1.64455
NUSAP1 nucleolar and spindle associated protein 1 -1.64426
SIPA1L3 signal-induced proliferation-associated 1 like 3 -1.64409
BTG1 B-cell translocation gene 1, anti-proliferative -1.64369
CDC25B cell division cycle 25B -1.64263
PTP4A1 protein tyrosine phosphatase type IVA, member 1 -1.63945
WDR45 WD repeat domain 45 -1.63931
LAMP2 lysosomal-associated membrane protein 2 -1.63709
CLEC11A C-type lectin domain family 11, member A -1.63366
H3F3B H3 histone, family 3B (H3.3B) -1.6238
C7ORF26 chromosome 7 open reading frame 26 -1.62039
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 -1.61113
PDIA6 protein disulfide isomerase family A, member 6 -1.60911
CBX6 chromobox homolog 6 -1.60856
COPS8 COP9 signalosome subunit 8 -1.60563
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -1.60286
SMAD3 SMAD family member 3 -1.60272
GPM6B glycoprotein M6B -1.60103
ASCC3 activating signal cointegrator 1 complex subunit 3 -1.59885
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -1.59799
CTNNBIP1 catenin, beta interacting protein 1 -1.59269
TUBB4B tubulin, beta 4B class IVb -1.5872
SSH3 slingshot protein phosphatase 3 -1.58597
CDYL chromodomain protein, Y-like -1.58126
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -1.57978
UBAP1 ubiquitin associated protein 1 -1.57353
CDR2L cerebellar degeneration-related protein 2-like -1.57093
METTL18 methyltransferase like 18 -1.56914
ADPGK ADP-dependent glucokinase -1.56842
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -1.56763
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -1.56654
PYGL phosphorylase, glycogen, liver -1.56417
COQ10B coenzyme Q10 homolog B (S. cerevisiae) -1.56063
UBE2C ubiquitin-conjugating enzyme E2C -1.55716
DUSP6 dual specificity phosphatase 6 -1.55694
HBEGF heparin-binding EGF-like growth factor -1.55321
ATF3 activating transcription factor 3 -1.55065
PLCL2 phospholipase C-like 2 -1.54877
C10ORF88 chromosome 10 open reading frame 88 -1.54404
CDC6 cell division cycle 6 -1.53836
IDS iduronate 2-sulfatase -1.53572
MICB MHC class I polypeptide-related sequence B -1.5338
FAM208A family with sequence similarity 208, member A -1.53308
CYLD cylindromatosis (turban tumor syndrome) -1.53114
CNOT1 CCR4-NOT transcription complex, subunit 1 -1.53015
RHEB Ras homolog enriched in brain -1.52889
PDZD8 PDZ domain containing 8 -1.52679
CTSB cathepsin B -1.52257
THOC5 THO complex 5 -1.5224
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 -1.52232
TXNL4B thioredoxin-like 4B -1.5197
EMILIN1 elastin microfibril interfacer 1 -1.51965
UVRAG UV radiation resistance associated -1.51825
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) -1.51213
PLAC8 placenta-specific 8 -1.51128
CCT2 chaperonin containing TCP1, subunit 2 (beta) -1.50992
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -1.50785
CEP63 centrosomal protein 63kDa -1.50535
CLEC1B C-type lectin domain family 1, member B -1.5053
DAZAP2 DAZ associated protein 2 -1.50291
BCL2 B-cell CLL/lymphoma 2 -1.5025
POU2AF1 POU class 2 associating factor 1 -1.50129
MDFIC MyoD family inhibitor domain containing -1.50024
MAPRE2 microtubule-associated protein, RP/EB family, member 2 -1.49384
ANKMY2 ankyrin repeat and MYND domain containing 2 -1.49381
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase -1.48958
MYLIP myosin regulatory light chain interacting protein -1.48686
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C -1.48425
LHFP lipoma HMGIC fusion partner -1.48071
B2M beta-2-microglobulin -1.47713
ATP13A1 ATPase type 13A1 -1.47582
AGA aspartylglucosaminidase -1.47498
GBP1 guanylate binding protein 1, interferon-inducible -1.47398
DOCK10 dedicator of cytokinesis 10 -1.47296
ZNF528 zinc finger protein 528 -1.47263
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma -1.47224
YPEL5 yippee-like 5 (Drosophila) -1.47153
RUNX3 runt-related transcription factor 3 -1.46955
MLX MLX, MAX dimerization protein -1.46821
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 -1.46821
BCAS2 breast carcinoma amplified sequence 2 -1.46795
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa -1.46391
PITPNA phosphatidylinositol transfer protein, alpha -1.46391
ADD3 adducin 3 (gamma) -1.46375
KPNA3 karyopherin alpha 3 (importin alpha 4) -1.45944
GPR183 G protein-coupled receptor 183 -1.45847
EREG epiregulin -1.45799
PARP16 poly (ADP-ribose) polymerase family, member 16 -1.45675
ADORA1 adenosine A1 receptor -1.45654
CD24 CD24 molecule -1.45516
DNTT DNA nucleotidylexotransferase -1.45384
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 -1.45279
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 -1.45059
SUMO1 small ubiquitin-like modifier 1 -1.44919
CD53 CD53 molecule -1.44869
CPT1A carnitine palmitoyltransferase 1A (liver) -1.44797
PRPS2 phosphoribosyl pyrophosphate synthetase 2 -1.44748
RRAGD Ras-related GTP binding D -1.44672
EPOR erythropoietin receptor -1.44564
MAP2K4 mitogen-activated protein kinase kinase 4 -1.44397
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 -1.4432
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 -1.44314
TFDP1 transcription factor Dp-1 -1.44231
RAB11B RAB11B, member RAS oncogene family -1.44117
HIST1H3A histone cluster 1, H3a -1.43882
AOAH acyloxyacyl hydrolase (neutrophil) -1.43654
RRM1 ribonucleotide reductase M1 -1.43575
COBLL1 cordon-bleu WH2 repeat protein-like 1 -1.43497
MRPL22 mitochondrial ribosomal protein L22 -1.4303
FAM49B family with sequence similarity 49, member B -1.42909
C11ORF95 chromosome 11 open reading frame 95 -1.42905
TOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast) -1.42853
UBC ubiquitin C -1.42843
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -1.42774
DUSP1 dual specificity phosphatase 1 -1.42728
KDM6B lysine (K)-specific demethylase 6B -1.42556
LSAMP limbic system-associated membrane protein -1.42494
COL18A1 collagen, type XVIII, alpha 1 -1.42448
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) -1.41977
TLE4 transducin-like enhancer of split 4 -1.41828
MEF2D myocyte enhancer factor 2D -1.41559
RRAS related RAS viral (r-ras) oncogene homolog -1.41319
XPA xeroderma pigmentosum, complementation group A -1.41081
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 -1.40987
GTSE1 G-2 and S-phase expressed 1 -1.40898
KRT7 keratin 7, type II -1.40846
MKI67 marker of proliferation Ki-67 -1.40612
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 -1.40436
TPR translocated promoter region, nuclear basket protein -1.39948
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 -1.39922
PTEN phosphatase and tensin homolog -1.39904
RPS4Y1 ribosomal protein S4, Y-linked 1 -1.39759
DTX4 deltex 4, E3 ubiquitin ligase -1.39515
KIF11 kinesin family member 11 -1.3924
PAM peptidylglycine alpha-amidating monooxygenase -1.38958
NNT nicotinamide nucleotide transhydrogenase -1.38766
MUS81 MUS81 structure-specific endonuclease subunit -1.38762
MYT1 myelin transcription factor 1 -1.38724
CALN1 calneuron 1 -1.38544
PTPRE protein tyrosine phosphatase, receptor type, E -1.38496
FOSB FBJ murine osteosarcoma viral oncogene homolog B -1.384
PFN1 profilin 1 -1.38312
CHEK1 checkpoint kinase 1 -1.38307
STAT5B signal transducer and activator of transcription 5B -1.38273
ZNF426 zinc finger protein 426 -1.38129
ZNF710 zinc finger protein 710 -1.37979
GPR107 G protein-coupled receptor 107 -1.37962
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -1.37787
PDE4B phosphodiesterase 4B, cAMP-specific -1.37687
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -1.37631
NIPBL Nipped-B homolog (Drosophila) -1.37416
C10ORF76 chromosome 10 open reading frame 76 -1.3726
KPNA6 karyopherin alpha 6 (importin alpha 7) -1.37259
SH2B3 SH2B adaptor protein 3 -1.37231
CD160 CD160 molecule -1.37157
SELL selectin L -1.37064
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -1.37063
NCOA2 nuclear receptor coactivator 2 -1.36968
MDFI MyoD family inhibitor -1.36911
PHF8 PHD finger protein 8 -1.3617
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) -1.35944
DCAKD dephospho-CoA kinase domain containing -1.35536
SRP72 signal recognition particle 72kDa -1.35306
QRICH1 glutamine-rich 1 -1.35299
PALMD palmdelphin -1.35185
CDK19 cyclin-dependent kinase 19 -1.3517
KRT76 keratin 76, type II -1.35148
H2AFX H2A histone family, member X -1.34768
SEC63 SEC63 homolog (S. cerevisiae) -1.34463
RAB27A RAB27A, member RAS oncogene family -1.34325
HGC6.3 uncharacterized LOC100128124 -1.34237
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 -1.33932
PTK2 protein tyrosine kinase 2 -1.33822
STK10 serine/threonine kinase 10 -1.33629
PDIA4 protein disulfide isomerase family A, member 4 -1.3334
RAD51 RAD51 recombinase -1.33334
CCNB2 cyclin B2 -1.33173
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -1.3312
ZNF614 zinc finger protein 614 -1.32798
NCAPG2 non-SMC condensin II complex, subunit G2 -1.32749
VRK3 vaccinia related kinase 3 -1.32451
FKBP8 FK506 binding protein 8, 38kDa -1.32346
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) -1.32341
HGF hepatocyte growth factor (hepapoietin A; scatter factor) -1.32298
KLF2 Kruppel-like factor 2 -1.31924
LAMB1 laminin, beta 1 -1.31891
CHP1 calcineurin-like EF-hand protein 1 -1.31766
CEP57 centrosomal protein 57kDa -1.31746
SOAT1 sterol O-acyltransferase 1 -1.31706