CAY-10397-7087 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the CAY-10397-7087 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACVR2A activin A receptor, type IIA
AKR1C2 aldo-keto reductase family 1, member C2
APLP1 amyloid beta (A4) precursor-like protein 1
ARG2 arginase 2
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARRB2 arrestin, beta 2
ATM ATM serine/threonine kinase
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BTN3A1 butyrophilin, subfamily 3, member A1
C9ORF114 chromosome 9 open reading frame 114
CACFD1 calcium channel flower domain containing 1
CCDC176 coiled-coil domain containing 176
CCPG1 cell cycle progression 1
CFLAR CASP8 and FADD-like apoptosis regulator
CHPF chondroitin polymerizing factor
CHST10 carbohydrate sulfotransferase 10
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CLTB clathrin, light chain B
CNKSR1 connector enhancer of kinase suppressor of Ras 1
COBL cordon-bleu WH2 repeat protein
COBLL1 cordon-bleu WH2 repeat protein-like 1
CTSF cathepsin F
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DDAH2 dimethylarginine dimethylaminohydrolase 2
DUSP8 dual specificity phosphatase 8
ECM1 extracellular matrix protein 1
ENDOD1 endonuclease domain containing 1
EPOR erythropoietin receptor
FAM49B family with sequence similarity 49, member B
FAS Fas cell surface death receptor
FPGS folylpolyglutamate synthase
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPER1 G protein-coupled estrogen receptor 1
HBEGF heparin-binding EGF-like growth factor
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOMER3 homer scaffolding protein 3
ICOSLG inducible T-cell co-stimulator ligand
IFI30 interferon, gamma-inducible protein 30
IL1RAP interleukin 1 receptor accessory protein
KIAA0930 KIAA0930
KLHL24 kelch-like family member 24
KRT8P12 keratin 8 pseudogene 12
LRRC37A3 leucine rich repeat containing 37, member A3
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAST4 microtubule associated serine/threonine kinase family member 4
METTL1 methyltransferase like 1
MFSD11 major facilitator superfamily domain containing 11
MR1 major histocompatibility complex, class I-related
MTERF4 mitochondrial transcription termination factor 4
NRSN2 neurensin 2
NSUN5P1 NOP2/Sun domain family, member 5 pseudogene 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAGR1 PAXIP1 associated glutamate-rich protein 1
PCGF2 polycomb group ring finger 2
PDLIM4 PDZ and LIM domain 4
PHIP pleckstrin homology domain interacting protein
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLXNA1 plexin A1
PRR3 proline rich 3
PTHLH parathyroid hormone-like hormone
RAD54B RAD54 homolog B (S. cerevisiae)
RNASE4 ribonuclease, RNase A family, 4
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
SAMD9 sterile alpha motif domain containing 9
SAYSD1 SAYSVFN motif domain containing 1
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SENP6 SUMO1/sentrin specific peptidase 6
SFTPB surfactant protein B
SIPA1 signal-induced proliferation-associated 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC35E1 solute carrier family 35, member E1
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SNRPA1 small nuclear ribonucleoprotein polypeptide A'
SNTA1 syntrophin, alpha 1
SNX27 sorting nexin family member 27
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SSH3 slingshot protein phosphatase 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STOM stomatin
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TGFB3 transforming growth factor, beta 3
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TOR4A torsin family 4, member A
TUBA3C tubulin, alpha 3c
TUBB2B tubulin, beta 2B class IIb
ULBP2 UL16 binding protein 2
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR13 WD repeat domain 13
WDR4 WD repeat domain 4
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZNF350 zinc finger protein 350
ZNF426 zinc finger protein 426
ZNF451 zinc finger protein 451

decreased expression

Symbol Name
ANG angiogenin, ribonuclease, RNase A family, 5
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARID3B AT rich interactive domain 3B (BRIGHT-like)
BCAS3 breast carcinoma amplified sequence 3
BOLA1 bolA family member 1
BPHL biphenyl hydrolase-like (serine hydrolase)
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C1ORF27 chromosome 1 open reading frame 27
CARD8 caspase recruitment domain family, member 8
CBS cystathionine-beta-synthase
CCNO cyclin O
CHRM3 cholinergic receptor, muscarinic 3
CLK4 CDC-like kinase 4
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CRIP1 cysteine-rich protein 1 (intestinal)
CRIP2 cysteine-rich protein 2
DCAF13 DDB1 and CUL4 associated factor 13
DCBLD2 discoidin, CUB and LCCL domain containing 2
DCLRE1A DNA cross-link repair 1A
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
EFNA4 ephrin-A4
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EML4 echinoderm microtubule associated protein like 4
EPHB6 EPH receptor B6
EPPK1 epiplakin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC5 exocyst complex component 5
FAM188A family with sequence similarity 188, member A
FBXL15 F-box and leucine-rich repeat protein 15
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GRPR gastrin-releasing peptide receptor
H1F0 H1 histone family, member 0
IGBP1 immunoglobulin (CD79A) binding protein 1
IRAK4 interleukin-1 receptor-associated kinase 4
KIF3A kinesin family member 3A
KPTN kaptin (actin binding protein)
LNPEP leucyl/cystinyl aminopeptidase
LTBP2 latent transforming growth factor beta binding protein 2
LYPD3 LY6/PLAUR domain containing 3
MAGEF1 melanoma antigen family F1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAPK3 mitogen-activated protein kinase 3
MRPL28 mitochondrial ribosomal protein L28
MUM1 melanoma associated antigen (mutated) 1
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NADSYN1 NAD synthetase 1
NPM3 nucleophosmin/nucleoplasmin 3
NPY1R neuropeptide Y receptor Y1
NSUN6 NOP2/Sun domain family, member 6
NTSR1 neurotensin receptor 1 (high affinity)
OVGP1 oviductal glycoprotein 1, 120kDa
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PAIP2B poly(A) binding protein interacting protein 2B
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PCOLCE procollagen C-endopeptidase enhancer
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PEX26 peroxisomal biogenesis factor 26
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLK2 polo-like kinase 2
PLXNB3 plexin B3
PRSS22 protease, serine, 22
PSENEN presenilin enhancer gamma secretase subunit
QTRT1 queuine tRNA-ribosyltransferase 1
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RHOC ras homolog family member C
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF31 ring finger protein 31
RPL13P5 ribosomal protein L13 pseudogene 5
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SAMHD1 SAM domain and HD domain 1
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SETD6 SET domain containing 6
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC31A2 solute carrier family 31 (copper transporter), member 2
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPANXC SPANX family, member C
TBCC tubulin folding cofactor C
TCTN2 tectonic family member 2
THAP7 THAP domain containing 7
TMEM159 transmembrane protein 159
TMEM209 transmembrane protein 209
TMEM8A transmembrane protein 8A
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
URM1 ubiquitin related modifier 1
VASH2 vasohibin 2
ZDHHC14 zinc finger, DHHC-type containing 14
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF358 zinc finger protein 358
ZNF552 zinc finger protein 552