CAY-10397-7082 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the CAY-10397-7082 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
APP amyloid beta (A4) precursor protein
ARFRP1 ADP-ribosylation factor related protein 1
ARL4C ADP-ribosylation factor-like 4C
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
AXIN1 axin 1
BIRC7 baculoviral IAP repeat containing 7
BRAP BRCA1 associated protein
C21ORF91 chromosome 21 open reading frame 91
CABIN1 calcineurin binding protein 1
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CACTIN cactin, spliceosome C complex subunit
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
DCTN1 dynactin 1
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
EFCAB2 EF-hand calcium binding domain 2
EGFR epidermal growth factor receptor
EHBP1L1 EH domain binding protein 1-like 1
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ELOVL2 ELOVL fatty acid elongase 2
EPHB3 EPH receptor B3
EPHX2 epoxide hydrolase 2, cytoplasmic
FADS2 fatty acid desaturase 2
FAM134B family with sequence similarity 134, member B
FANCA Fanconi anemia, complementation group A
FBXL2 F-box and leucine-rich repeat protein 2
FBXO2 F-box protein 2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCF1 FCF1 rRNA-processing protein
FOSL1 FOS-like antigen 1
FSCN1 fascin actin-bundling protein 1
GALC galactosylceramidase
GLIPR1 GLI pathogenesis-related 1
GPR157 G protein-coupled receptor 157
GSTA4 glutathione S-transferase alpha 4
HABP4 hyaluronan binding protein 4
HDGFRP3 hepatoma-derived growth factor, related protein 3
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HIST1H1D histone cluster 1, H1d
HK2 hexokinase 2
HLA-G major histocompatibility complex, class I, G
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HYAL2 hyaluronoglucosaminidase 2
IGHMBP2 immunoglobulin mu binding protein 2
INF2 inverted formin, FH2 and WH2 domain containing
INPP5K inositol polyphosphate-5-phosphatase K
IRF2BP1 interferon regulatory factor 2 binding protein 1
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCTD15 potassium channel tetramerization domain containing 15
KDM6A lysine (K)-specific demethylase 6A
LMNA lamin A/C
MALT1 MALT1 paracaspase
MAN2A2 mannosidase, alpha, class 2A, member 2
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MMP9 matrix metallopeptidase 9
MVK mevalonate kinase
MYOF myoferlin
NF2 neurofibromin 2 (merlin)
NOP14-AS1 NOP14 antisense RNA 1
NPM3 nucleophosmin/nucleoplasmin 3
NR6A1 nuclear receptor subfamily 6, group A, member 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
ORAI2 ORAI calcium release-activated calcium modulator 2
PALM paralemmin
PCDH1 protocadherin 1
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G15 phospholipase A2, group XV
PRDX2 peroxiredoxin 2
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAD50 RAD50 homolog (S. cerevisiae)
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RBM19 RNA binding motif protein 19
RNF121 ring finger protein 121
RNF24 ring finger protein 24
RPL23AP32 ribosomal protein L23a pseudogene 32
RSL1D1 ribosomal L1 domain containing 1
SH3BP2 SH3-domain binding protein 2
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
TADA2A transcriptional adaptor 2A
TAOK1 TAO kinase 1
TAZ tafazzin
TBC1D22A TBC1 domain family, member 22A
THBS3 thrombospondin 3
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TP53I11 tumor protein p53 inducible protein 11
USP22 ubiquitin specific peptidase 22
USP36 ubiquitin specific peptidase 36
WSB1 WD repeat and SOCS box containing 1
ZC3H7B zinc finger CCCH-type containing 7B
ZFHX2 zinc finger homeobox 2
ZNF180 zinc finger protein 180
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ACOT8 acyl-CoA thioesterase 8
ACYP1 acylphosphatase 1, erythrocyte (common) type
ARMC4 armadillo repeat containing 4
ATAD3A ATPase family, AAA domain containing 3A
ATG9A autophagy related 9A
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
C1ORF56 chromosome 1 open reading frame 56
CD82 CD82 molecule
CDH18 cadherin 18, type 2
CENPC centromere protein C
CGREF1 cell growth regulator with EF-hand domain 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DGAT1 diacylglycerol O-acyltransferase 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ENAH enabled homolog (Drosophila)
ERF Ets2 repressor factor
EXOC5 exocyst complex component 5
F8 coagulation factor VIII, procoagulant component
FGD1 FYVE, RhoGEF and PH domain containing 1
FUZ fuzzy planar cell polarity protein
GAR1 GAR1 ribonucleoprotein
GMCL1 germ cell-less, spermatogenesis associated 1
GMEB1 glucocorticoid modulatory element binding protein 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPATCH3 G patch domain containing 3
HDAC4 histone deacetylase 4
HOXC8 homeobox C8
HSPA1L heat shock 70kDa protein 1-like
IFI35 interferon-induced protein 35
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IREB2 iron-responsive element binding protein 2
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIF13A kinesin family member 13A
KLHL25 kelch-like family member 25
LIG4 ligase IV, DNA, ATP-dependent
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC37A2 leucine rich repeat containing 37, member A2
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBTD1 mbt domain containing 1
METTL2B methyltransferase like 2B
MIS18BP1 MIS18 binding protein 1
MPDU1 mannose-P-dolichol utilization defect 1
NPY1R neuropeptide Y receptor Y1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PADI2 peptidyl arginine deiminase, type II
PAQR3 progestin and adipoQ receptor family member III
PER3 period circadian clock 3
PGPEP1 pyroglutamyl-peptidase I
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PODNL1 podocan-like 1
PYGB phosphorylase, glycogen; brain
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RASAL1 RAS protein activator like 1 (GAP1 like)
RFX7 regulatory factor X, 7
RGS17 regulator of G-protein signaling 17
RNF25 ring finger protein 25
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPAP2 RNA polymerase II associated protein 2
SERTAD3 SERTA domain containing 3
SH2B3 SH2B adaptor protein 3
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC12A9 solute carrier family 12, member 9
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC25A40 solute carrier family 25, member 40
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC35E3 solute carrier family 35, member E3
SLC41A3 solute carrier family 41, member 3
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SNHG20 small nucleolar RNA host gene 20
SPIN1 spindlin 1
STX1A syntaxin 1A (brain)
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TCTN2 tectonic family member 2
TESC tescalcin
TKFC triokinase/FMN cyclase
TMEM159 transmembrane protein 159
TMEM38B transmembrane protein 38B
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TRABD TraB domain containing
TRAPPC11 trafficking protein particle complex 11
TRIM32 tripartite motif containing 32
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
VLDLR very low density lipoprotein receptor
WRN Werner syndrome, RecQ helicase-like
WWC2 WW and C2 domain containing 2
ZNF205 zinc finger protein 205
ZNF211 zinc finger protein 211
ZNF254 zinc finger protein 254
ZNF280D zinc finger protein 280D
ZW10 zw10 kinetochore protein