Bronchitis Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A bronchial disease that is an inflammation of the bronchial tubes. It is caused by bacteria and viruses. The disease has_symptom cough with mucus, has_symptom shortness of breath, has_symptom low fever and has_symptom chest tightness. (Human Disease Ontology, DOID_6132)
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Genes

24 genes associated with the Bronchitis phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
COMT catechol-O-methyltransferase
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
EGFR epidermal growth factor receptor
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
IL13 interleukin 13
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IRF4 interferon regulatory factor 4
MARCO macrophage receptor with collagenous structure
MMP1 matrix metallopeptidase 1
MPO myeloperoxidase
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
NQO1 NAD(P)H dehydrogenase, quinone 1
PON1 paraoxonase 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TNF tumor necrosis factor