Bronchiolitis Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A lung disease that is an inflammation of the bronchioles, the smallest air passages of the lungs. It is caused by viruses and bacteria. The disease has_symptom cough, has_symptom wheezing, has_symptom shortness of breath, has_symptom fever, has_symptom nasal flaring in infants and has_symptom bluish skin due to lack of oxygen. (Human Disease Ontology, DOID_2942)
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Genes

32 genes associated with the Bronchiolitis phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
CCL5 chemokine (C-C motif) ligand 5
CD14 CD14 molecule
CXCL8 chemokine (C-X-C motif) ligand 8
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IFNL3 interferon, lambda 3
IL10 interleukin 10
IL17A interleukin 17A
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
IL9 interleukin 9
JUN jun proto-oncogene
MBL2 mannose-binding lectin (protein C) 2, soluble
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
SELE selectin E
TLR1 toll-like receptor 1
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TNF tumor necrosis factor
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
Funding