Breast cancer Gene Set

Dataset GWAS Catalog SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A thoracic cancer that originates in the mammary gland. (Human Disease Ontology, DOID_1612)
External Link https://www.ebi.ac.uk/gwas/search?query=Breast cancer
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Genes

53 genes associated with the Breast cancer phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
FGFR2 fibroblast growth factor receptor 2 2.21769
CASC16 cancer susceptibility candidate 16 (non-protein coding) 1.97969
ZNF365 zinc finger protein 365 1.37125
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 1.28559
EMBP1 embigin pseudogene 1 1.20529
ZMIZ1 zinc finger, MIZ-type containing 1 1.09648
CCDC170 coiled-coil domain containing 170 1.08247
RAD51B RAD51 paralog B 1.00661
MKL1 megakaryoblastic leukemia (translocation) 1 0.989242
CDYL2 chromodomain protein, Y-like 2 0.896275
ADAM29 ADAM metallopeptidase domain 29 0.881997
DIRC3 disrupted in renal carcinoma 3 0.863028
ELL elongation factor RNA polymerase II 0.831366
EBF1 early B-cell factor 1 0.802698
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.786836
FTO fat mass and obesity associated 0.77738
ERBB4 erb-b2 receptor tyrosine kinase 4 0.767895
STXBP4 syntaxin binding protein 4 0.750033
PAX9 paired box 9 0.750033
BABAM1 BRISC and BRCA1 A complex member 1 0.715598
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.696558
MDM4 MDM4, p53 regulator 0.696558
TERT telomerase reverse transcriptase 0.673878
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 0.602611
PEX14 peroxisomal biogenesis factor 14 0.572839
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.572839
CCDC88C coiled-coil domain containing 88C 0.552116
EMID1 EMI domain containing 1 0.483518
LGR6 leucine-rich repeat containing G protein-coupled receptor 6 0.434785
RALY RALY heterogeneous nuclear ribonucleoprotein 0.434785
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.405958
PDE4D phosphodiesterase 4D, cAMP-specific 0.389385
CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 0.389385
RNF146 ring finger protein 146 0.389385
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.389385
TET2 tet methylcytosine dioxygenase 2 0.377988
ANKLE1 ankyrin repeat and LEM domain containing 1 0.377988
BRCA2 breast cancer 2, early onset 0.369252
COL1A1 collagen, type I, alpha 1 0.351407
SIAH2 siah E3 ubiquitin protein ligase 2 0.346786
LOC101927835 uncharacterized LOC101927835 0.266721
ADAMTS7P3 ADAMTS7 pseudogene 3 0.246511
TNNT3 troponin T type 3 (skeletal, fast) 0.246511
ESR1 estrogen receptor 1 0.165905
ROPN1L rhophilin associated tail protein 1-like 0.165905
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.165905
ATE1 arginyltransferase 1 0.165905
LOC101927285 uncharacterized LOC101927285 0.085234
FBN1 fibrillin 1 0.070053
GRIK1 glutamate receptor, ionotropic, kainate 1 0.070053
LINC-PINT long intergenic non-protein coding RNA, p53 induced transcript 0.070053
ZNF577 zinc finger protein 577 0.057619
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.042592