Brain Neoplasms Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D001932
Similar Terms
Downloads & Tools

Genes

361 genes/proteins associated with the disease Brain Neoplasms from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
IL2 interleukin 2 2.88009
DLL1 delta-like 1 (Drosophila) 2.88009
SPP1 secreted phosphoprotein 1 2.88009
PON1 paraoxonase 1 2.88009
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.88009
SIRT1 sirtuin 1 2.88009
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 2.88009
DTX2 deltex 2, E3 ubiquitin ligase 2.88009
TP53 tumor protein p53 2.88009
CCND1 cyclin D1 2.88009
VEGFA vascular endothelial growth factor A 2.88009
DAPK1 death-associated protein kinase 1 2.88009
NRARP NOTCH-regulated ankyrin repeat protein 2.88009
MGMT O-6-methylguanine-DNA methyltransferase 2.88009
PTCH1 patched 1 2.88009
HES5 hes family bHLH transcription factor 5 2.88009
ALK anaplastic lymphoma receptor tyrosine kinase 2.88009
SOD2 superoxide dismutase 2, mitochondrial 2.88009
TGM2 transglutaminase 2 2.88009
SMO smoothened, frizzled class receptor 2.88009
CDKN2A cyclin-dependent kinase inhibitor 2A 2.88009
CDK4 cyclin-dependent kinase 4 2.88009
PCNA proliferating cell nuclear antigen 2.88009
EML4 echinoderm microtubule associated protein like 4 2.88009
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 2.04842
BCL2 B-cell CLL/lymphoma 2 2.02211
BAX BCL2-associated X protein 2.01979
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.98568
GSTM1 glutathione S-transferase mu 1 1.95041
JUN jun proto-oncogene 1.93953
BCL2L1 BCL2-like 1 1.91051
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.84658
TNF tumor necrosis factor 1.84108
GSTT1 glutathione S-transferase theta 1 1.83912
GSTP1 glutathione S-transferase pi 1 1.83663
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.83503
VCAM1 vascular cell adhesion molecule 1 1.82569
F3 coagulation factor III (thromboplastin, tissue factor) 1.82254
HMOX1 heme oxygenase 1 1.81243
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.80924
CD44 CD44 molecule (Indian blood group) 1.80472
PARP1 poly (ADP-ribose) polymerase 1 1.80115
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.7935
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.78511
GADD45A growth arrest and DNA-damage-inducible, alpha 1.76966
FOS FBJ murine osteosarcoma viral oncogene homolog 1.75102
IL6 interleukin 6 1.7448
H2AFX H2A histone family, member X 1.73838
TOP2A topoisomerase (DNA) II alpha 170kDa 1.73838
ERBB2 erb-b2 receptor tyrosine kinase 2 1.73129
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.70947
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.70947
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.70326
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.6857
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.67933
CCL2 chemokine (C-C motif) ligand 2 1.67311
CCNB1 cyclin B1 1.67202
RB1 retinoblastoma 1 1.6636
BAK1 BCL2-antagonist/killer 1 1.65204
FAS Fas cell surface death receptor 1.63765
FASLG Fas ligand (TNF superfamily, member 6) 1.63608
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.61897
HSPB1 heat shock 27kDa protein 1 1.60851
CAT catalase 1.60337
CCNE1 cyclin E1 1.59849
MT2A metallothionein 2A 1.58537
THBS1 thrombospondin 1 1.5816
CYCS cytochrome c, somatic 1.56755
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.55971
NQO1 NAD(P)H dehydrogenase, quinone 1 1.55921
GCLC glutamate-cysteine ligase, catalytic subunit 1.55797
TNC tenascin C 1.55698
GDF15 growth differentiation factor 15 1.55133
BAD BCL2-associated agonist of cell death 1.54986
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.54111
MCL1 myeloid cell leukemia 1 1.53481
CXCL2 chemokine (C-X-C motif) ligand 2 1.52816
BTG2 BTG family, member 2 1.52767
DUSP1 dual specificity phosphatase 1 1.52262
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.52161
ICAM1 intercellular adhesion molecule 1 1.5186
SDC1 syndecan 1 1.5128
HSPA1A heat shock 70kDa protein 1A 1.5123
PRC1 protein regulator of cytokinesis 1 1.50323
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.49813
BID BH3 interacting domain death agonist 1.49711
TYMS thymidylate synthetase 1.48941
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.4871
MT1A metallothionein 1A 1.48479
OGG1 8-oxoguanine DNA glycosylase 1.48119
CDK2 cyclin-dependent kinase 2 1.47864
S100A8 S100 calcium binding protein A8 1.47736
ATF3 activating transcription factor 3 1.474
BBC3 BCL2 binding component 3 1.47115
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.46595
CCNG1 cyclin G1 1.4612
NGF nerve growth factor (beta polypeptide) 1.46067
BIRC2 baculoviral IAP repeat containing 2 1.45936
CFLAR CASP8 and FADD-like apoptosis regulator 1.45537
IL1A interleukin 1, alpha 1.45326
CDK1 cyclin-dependent kinase 1 1.45089
XDH xanthine dehydrogenase 1.43782
MPO myeloperoxidase 1.43673
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.43646
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.43401
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.4294
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.42535
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.42074
BIRC5 baculoviral IAP repeat containing 5 1.4202
ODC1 ornithine decarboxylase 1 1.41992
LCN2 lipocalin 2 1.41856
EGFR epidermal growth factor receptor 1.41091
MMP3 matrix metallopeptidase 3 1.40148
MAPK1 mitogen-activated protein kinase 1 1.39535
INA internexin neuronal intermediate filament protein, alpha 1.39394
CTSL cathepsin L 1.39254
MAPK8 mitogen-activated protein kinase 8 1.3917
COL1A1 collagen, type I, alpha 1 1.3917
VCAN versican 1.3903
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.38355
TGFB1 transforming growth factor, beta 1 1.37733
IGFBP3 insulin-like growth factor binding protein 3 1.37075
FN1 fibronectin 1 1.36961
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.36533
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.36161
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.35877
NOS2 nitric oxide synthase 2, inducible 1.35473
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.35386
IL1B interleukin 1, beta 1.35213
GPX1 glutathione peroxidase 1 1.34869
CXCL8 chemokine (C-X-C motif) ligand 8 1.34635
COL4A1 collagen, type IV, alpha 1 1.33612
IGF1 insulin-like growth factor 1 (somatomedin C) 1.33612
IER3 immediate early response 3 1.33612
KRT8 keratin 8, type II 1.33228
GSK3B glycogen synthase kinase 3 beta 1.33199
SRGN serglycin 1.33169
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.33081
CCND3 cyclin D3 1.33052
DDIT3 DNA-damage-inducible transcript 3 1.32816
MAPK3 mitogen-activated protein kinase 3 1.32577
FGF2 fibroblast growth factor 2 (basic) 1.32518
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.32488
EDNRB endothelin receptor type B 1.3228
TIMP1 TIMP metallopeptidase inhibitor 1 1.32221
NFE2L2 nuclear factor, erythroid 2-like 2 1.32103
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.31566
CXCL5 chemokine (C-X-C motif) ligand 5 1.30941
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 1.30696
S100A4 S100 calcium binding protein A4 1.30147
ALB albumin 1.30056
CHEK1 checkpoint kinase 1 1.2975
IFNG interferon, gamma 1.29626
CD14 CD14 molecule 1.28889
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.28889
UBE2C ubiquitin-conjugating enzyme E2C 1.28425
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 1.28027
AURKA aurora kinase A 1.27966
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.27875
EGF epidermal growth factor 1.27751
TFPI2 tissue factor pathway inhibitor 2 1.27657
CCNA2 cyclin A2 1.27502
PRKCD protein kinase C, delta 1.27039
TAGLN transgelin 1.26794
SLPI secretory leukocyte peptidase inhibitor 1.26607
FKBP5 FK506 binding protein 5 1.26576
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.26514
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.26236
F2 coagulation factor II (thrombin) 1.26236
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.25899
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.25619
S100A9 S100 calcium binding protein A9 1.25059
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.24874
WISP1 WNT1 inducible signaling pathway protein 1 1.24812
BIRC3 baculoviral IAP repeat containing 3 1.24687
PPARD peroxisome proliferator-activated receptor delta 1.24623
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.24465
DHRS3 dehydrogenase/reductase (SDR family) member 3 1.23392
TYMP thymidine phosphorylase 1.23392
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.2336
CDC25C cell division cycle 25C 1.23169
MAP2K1 mitogen-activated protein kinase kinase 1 1.23042
STMN1 stathmin 1 1.22948
APAF1 apoptotic peptidase activating factor 1 1.22566
CTGF connective tissue growth factor 1.22469
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.22145
CD36 CD36 molecule (thrombospondin receptor) 1.22048
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.21951
PTEN phosphatase and tensin homolog 1.21759
PLAT plasminogen activator, tissue 1.21759
CD274 CD274 molecule 1.21727
PKP2 plakophilin 2 1.21727
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.21567
TLR4 toll-like receptor 4 1.21337
RSRP1 arginine/serine-rich protein 1 1.21239
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 1.21173
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.21173
STAT1 signal transducer and activator of transcription 1, 91kDa 1.21043
GJA1 gap junction protein, alpha 1, 43kDa 1.21043
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.20784
VIM vimentin 1.20751
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.20719
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.2059
IL4 interleukin 4 1.20558
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 1.20427
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.20427
ERBB3 erb-b2 receptor tyrosine kinase 3 1.20427
HRAS Harvey rat sarcoma viral oncogene homolog 1.20196
EP300 E1A binding protein p300 1.2013
COL3A1 collagen, type III, alpha 1 1.19639
CHEK2 checkpoint kinase 2 1.19477
GPX3 glutathione peroxidase 3 1.19477
INSIG1 insulin induced gene 1 1.19477
BRCA1 breast cancer 1, early onset 1.19279
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.19113
GSR glutathione reductase 1.19047
FSHR follicle stimulating hormone receptor 1.18948
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.18915
FOXF2 forkhead box F2 1.18783
DCT dopachrome tautomerase 1.18521
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.18326
CRYAB crystallin, alpha B 1.18193
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.17761
RPS27L ribosomal protein S27-like 1.17662
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.17662
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 1.17662
TRIB3 tribbles pseudokinase 3 1.17333
SPON1 spondin 1, extracellular matrix protein 1.17235
CTSB cathepsin B 1.17134
SP1 Sp1 transcription factor 1.16967
ATF4 activating transcription factor 4 1.16799
C3 complement component 3 1.16302
MAPK9 mitogen-activated protein kinase 9 1.1607
IGF1R insulin-like growth factor 1 receptor 1.15797
BTG1 B-cell translocation gene 1, anti-proliferative 1.15729
TIMP2 TIMP metallopeptidase inhibitor 2 1.15627
PRL prolactin 1.1556
GSTA2 glutathione S-transferase alpha 2 1.15458
AKR1C3 aldo-keto reductase family 1, member C3 1.1529
IGFBP7 insulin-like growth factor binding protein 7 1.15256
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 1.15256
FOSL1 FOS-like antigen 1 1.15122
SOD1 superoxide dismutase 1, soluble 1.14989
GCLM glutamate-cysteine ligase, modifier subunit 1.14954
GRB10 growth factor receptor-bound protein 10 1.14885
TRAF2 TNF receptor-associated factor 2 1.14885
GOLGA8B golgin A8 family, member B 1.1485
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.14816
COL1A2 collagen, type I, alpha 2 1.14816
NOX4 NADPH oxidase 4 1.14781
AKR1C1 aldo-keto reductase family 1, member C1 1.14644
EGR1 early growth response 1 1.14438
DPYD dihydropyrimidine dehydrogenase 1.14302
IL10 interleukin 10 1.14234
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.14166
IL12B interleukin 12B 1.14132
TUBB tubulin, beta class I 1.14132
MAPK14 mitogen-activated protein kinase 14 1.13895
PLAU plasminogen activator, urokinase 1.13862
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.13862
SFRP2 secreted frizzled-related protein 2 1.13758
TRAF1 TNF receptor-associated factor 1 1.13758
INHBA inhibin, beta A 1.13415
S100P S100 calcium binding protein P 1.12703
MAP2K4 mitogen-activated protein kinase kinase 4 1.12357
BMP4 bone morphogenetic protein 4 1.12288
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 1.12014
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.12014
AXL AXL receptor tyrosine kinase 1.12014
IL1R1 interleukin 1 receptor, type I 1.11877
DHFR dihydrofolate reductase 1.11877
LDLR low density lipoprotein receptor 1.11707
MAP2K3 mitogen-activated protein kinase kinase 3 1.11673
CCL5 chemokine (C-C motif) ligand 5 1.11639
FMOD fibromodulin 1.11639
GADD45G growth arrest and DNA-damage-inducible, gamma 1.11431
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.11255
PRNP prion protein 1.1122
ATP7A ATPase, Cu++ transporting, alpha polypeptide 1.11011
CREBBP CREB binding protein 1.11011
ATF5 activating transcription factor 5 1.10665
CD58 CD58 molecule 1.10459
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.10424
HBEGF heparin-binding EGF-like growth factor 1.10424
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 1.10353
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.10246
MKI67 marker of proliferation Ki-67 1.10246
MMP9 matrix metallopeptidase 9 1.10104
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.10104
CCAR1 cell division cycle and apoptosis regulator 1 1.09822
MMP1 matrix metallopeptidase 1 1.09822
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.09786
LDHA lactate dehydrogenase A 1.09611
MMP2 matrix metallopeptidase 2 1.09541
DUSP4 dual specificity phosphatase 4 1.09401
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.09401
RAD51 RAD51 recombinase 1.0919
AKAP12 A kinase (PRKA) anchor protein 12 1.09083
G6PD glucose-6-phosphate dehydrogenase 1.08975
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.08833
EPO erythropoietin 1.08797
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 1.08478
LBP lipopolysaccharide binding protein 1.08478
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1.08407
CYBB cytochrome b-245, beta polypeptide 1.08231
RGS4 regulator of G-protein signaling 4 1.07589
VWF von Willebrand factor 1.07305
IRS1 insulin receptor substrate 1 1.06881
RRM2 ribonucleotide reductase M2 1.06881
CYR61 cysteine-rich, angiogenic inducer, 61 1.06881
ANXA4 annexin A4 1.06734
TXNIP thioredoxin interacting protein 1.06698
SRXN1 sulfiredoxin 1 1.06698
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 1.06188
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.06152
APC adenomatous polyposis coli 1.06152
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 1.059
FYN FYN proto-oncogene, Src family tyrosine kinase 1.05864
IL1RN interleukin 1 receptor antagonist 1.05793
KCTD12 potassium channel tetramerization domain containing 12 1.05648
TH tyrosine hydroxylase 1.05386
MAOA monoamine oxidase A 1.05237
CD151 CD151 molecule (Raph blood group) 1.05126
SOCS3 suppressor of cytokine signaling 3 1.05089
BCL2A1 BCL2-related protein A1 1.04757
POR P450 (cytochrome) oxidoreductase 1.04757
CXCL10 chemokine (C-X-C motif) ligand 10 1.04611
NUPR1 nuclear protein, transcriptional regulator, 1 1.04538
THBD thrombomodulin 1.04501
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 1.04501
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.04352
SAT1 spermidine/spermine N1-acetyltransferase 1 1.04239
PCOLCE procollagen C-endopeptidase enhancer 1.04201
PHGDH phosphoglycerate dehydrogenase 1.03976
IL12A interleukin 12A 1.03827
E2F1 E2F transcription factor 1 1.03827
NBL1 neuroblastoma 1, DAN family BMP antagonist 1.03752
MARCKS myristoylated alanine-rich protein kinase C substrate 1.03715
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 1.03715
NCF2 neutrophil cytosolic factor 2 1.03715
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.03641
MSH2 mutS homolog 2 1.03456
MAP2K6 mitogen-activated protein kinase kinase 6 1.03456
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 1.03235
DCN decorin 1.03197
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.02971
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.02858
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.02821
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 1.02671
MPG N-methylpurine-DNA glycosylase 1.02485
PPIB peptidylprolyl isomerase B (cyclophilin B) 1.0241
VLDLR very low density lipoprotein receptor 1.02188
CCNG2 cyclin G2 1.01928
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.01928
CDKN3 cyclin-dependent kinase inhibitor 3 1.01928
HSF1 heat shock transcription factor 1 1.01701
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.01474
DIABLO diablo, IAP-binding mitochondrial protein 1.01437
EDN1 endothelin 1 1.01249
COL4A2 collagen, type IV, alpha 2 1.01137
RFC5 replication factor C (activator 1) 5, 36.5kDa 1.01137